Pyruvate Catabolism (Clostridium thermocellum)

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Name	Type	Database reference	Comment
1,4-α-Branching Enzyme	GeneProduct	4810907 (Entrez Gene)	Cthe 2191, 1,4-α-Debranching Enzyme
2 H+	Metabolite	12408-02-5 (CAS)
2-Phosphoglyceric acid	Metabolite	2553-59-5 (CAS)
3-Phosphoglyceric acid	Metabolite	17794 (ChEBI)
6-Phosphofructokinase	GeneProduct	4808496 (Entrez Gene)	Cthe 0347
6-Phosphofructokinase	GeneProduct	4809766 (Entrez Gene)	Cthe 1261
ABC transporter-like protein (ATPase component)	Protein	4809413 (Entrez Gene)	Cthe 2128 (sugar binding periplasmic protein
ABC transporter-like protein	Protein	4809826 (Entrez Gene)	Cthe 2447
ABC transporter-like protein	Protein	4811175 (Entrez Gene)	Cthe 0391 ABC transporter-like protein putative sugar ABC transporter ATP-binding protein
ABC transporter	Protein	4808396 (Entrez Gene)	Cthe 0393 sugar ABC transporter sugar-binding protein
ABC-type sugar	Protein	4809825 (Entrez Gene)	Cthe 2446 ABC-type sugar transport system periplasmic component-like protein (D-ribose transport system ATP-binding protein)
ADP-Glucose	Metabolite	15751 (ChEBI)
ADP-glucose type glycogen/starch synthase	GeneProduct	4808565 (Entrez Gene)	Cthe 0282, ADP-glucose type glycogen/starch synthase
ADP-glucose type glycogen/starch synthase	GeneProduct	4809536 (Entrez Gene)	Cthe 1284, ADP-glucose type glycogen/starch synthase
ADP	Metabolite	58-64-0 (ChEBI)
AMP-dependent synthetase and ligase	Protein	19926-71-7 (CAS)	Cthe 0551, Acetate Thiokinase
AMP	Metabolite	61-19-8 (CAS)
ATP	Metabolite	56-65-5 (ChEBI)
ATPase	Protein	4811174 (Entrez Gene)	MoxR-like ATPases
Acetaldehyde	Metabolite	75-07-0 (CAS)
Acetaldhyde Dehydrogenase/Alcohol Dehydrogenase	GeneProduct	4808426 (Entrez Gene)	Cthe 0423
Acetate	Metabolite	758-12-3 (CAS)
AcetylCoA	Metabolite	72-89-9 (CAS)
Biotin/lipoyl attachment protein	Protein	4810318 (Entrez Gene)	Cthe 0700
Bisphosphoglyceric acid	Metabolite	1981-49-3 (CAS)
C02	Metabolite	124-38-9 (CAS)
Carboxyl transferase	Protein	4810317 (Entrez Gene)	Cthe 0699
Cellobiose Phosphorylase	GeneProduct	4808558 (Entrez Gene)	Cthe 0275
Cellobiose	Metabolite	17057 (ChEBI)
Cellotriose	Metabolite	33404-34-1 (CAS)
Cellulose	Metabolite	18246 (ChEBI)
D-Cellotetraose	Metabolite	38819-01-1 (CAS)
D-Glucose	Metabolite	4146 (ChEBI)
D-xylulose-5-P	Metabolite	60802-29-1 (CAS)
Dihydroxyacetone phosphate	Metabolite	57-04-5 (CAS)
Endoglucanase	GeneProduct	4808805 (Entrez Gene)
Eno Phosphopyruvate Hydratase	GeneProduct	4808701 (Entrez Gene)	Enolase equivalent, Cthe 0143
Ethanol	Metabolite	64-17-5 (CAS)
Fe-Containing ADH	GeneProduct	4808397 (Entrez Gene)	Cthe 0394, iron-containing alcohol dehydrogenase
Fe-Containing ADH	GeneProduct	4808725 (Entrez Gene)	Cthe 0101, iron-containing alcohol dehydrogenase
Ferredoxin - Ox	GeneProduct	4808489 (Entrez Gene)	Cthe 0340, [2Fe-2S] Ferredoxin (Fd)
Ferrodoxin - Red	GeneProduct	4808489 (Entrez Gene)	Cthe 0340, [2Fe-2S] Ferredoxin (Fd)
Formate acetyltransferase	GeneProduct	4808305 (Entrez Gene)	Cthe 0505, Pyruvate:Formate Lyase (& AE)
Formate	Metabolite	15740 (ChEBI)
Fructose-1,6-Biphosphate	Metabolite	488-69-7 (CAS)
Fructose-6-Phosphate	Metabolite	643-13-0 (CAS)
Fructose-bisphosphate Aldolase	GeneProduct	4808498 (Entrez Gene)	Cthe 0349, (Cthe 2938 no protein detected)
Fructose-bisphosphate aldolase	GeneProduct	4808498 (Entrez Gene)	Cthe 0349
GlgD subunit	GeneProduct	4809617 (Entrez Gene)	Cthe_3167, glucose-1-phosphate adenylyltransferase, GlgD subunit
Glucokinase	GeneProduct	4810221 (Entrez Gene)	hexokinase, Cthe 2938, (Cthe 0390 no detectable protein)
Glucose-1-phosphate adenylyltransferase	GeneProduct	4809616 (Entrez Gene)	Cthe 3166, glgC glucose-1-phosphate adenylyltransferase
Glucose-6-Phosphate	Metabolite	4170 (ChEBI)
Glucose-6-phosphate Isomerase	GeneProduct	4808635 (Entrez Gene)	Cthe 0217
Glyceraldehyde 3-phosphate	Metabolite	142-10-9 (CAS)
Glyceraldehyde-3-P	Metabolite	142-10-9 (ChEBI)
Glyceraldehyde-3-Phosphate Dehydrogense	GeneProduct	4808695 (Entrez Gene)	Cthe 0137
Glycogen Debranching Enzyme	GeneProduct	4808741 (Entrez Gene)	Cthe 0115, 1,4-a-Debranching Enzyme
Glycogen, Amylase (1,4-α)	Metabolite	9014-71-5 (CAS)
Glycogen, Starch	Metabolite	HMDB00757 (HMDB)
Glycosyltransferase	GeneProduct	4809913 (Entrez Gene)	Cthe 1221
Glycosyltransferase	GeneProduct	4811137 (Entrez Gene)	Cthe 2989
H2	Metabolite	1333-74-0 (CAS)
Hydrogenase, Fe-only	GeneProduct	4808491 (Entrez Gene)	Cthe 0342, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
Hydrogenase, Fe-only	GeneProduct	4811152 (Entrez Gene)	Cthe 3004, ferredoxin, FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Hydrogenase, Subunit Fe-only	GeneProduct	4811151 (Entrez Gene)	Cthe 3003, 4Fe-4S ferredoxin, iron-sulfur binding; iron hydrogenase, small subunit; hydrogenase large subunit-like
Indolepyruvate oxidoreductase subunit ɗ	GeneProduct	4808216 (Entrez Gene)	Cthe 0614, indolepyruvate oxidoreductase subunit beta
Inner-membrane translocator	Protein	4808395 (Entrez Gene)
Innermembrane Translocator	Protein	4809827 (Entrez Gene)	Cthe 2448
L-Lactate Dehydrogenase	GeneProduct	4811351 (Entrez Gene)	Cthe 1053
Lactate	Metabolite	16651 (ChEBI)
Malate Dehydrogenase (NAD)	GeneProduct	4808494 (Entrez Gene)	Cthe 0345
Malate Dehydrogenase	GeneProduct	4808493 (Entrez Gene)	Cthe 0344
Malate	Metabolite	6915-15-7 (CAS)
NAD+	Metabolite	53-54-9 (CAS)
NADH dehydrogenase (quinone)	GeneProduct	4808357 (Entrez Gene)	Cthe 0429
NADH dehydrogenase (quinone)	GeneProduct	4808490 (Entrez Gene)	Cthe 0341
NADH dehydrogenase (ubquinone)	GeneProduct	4808431 (Entrez Gene)	Cthe 0428, NADH dehydrogenase (ubiquinone), 24 kDa subunit
NADH	Metabolite	53-68-4 (CAS)
NADP+	Metabolite	53-59-8 (CAS)
NADPH	Metabolite	53-59-8 (CAS)
Oxaloacetate Decarboxylase	Protein	4810319 (Entrez Gene)	Cthe 0701
Oxaloacetic Acid	Metabolite	328-42-7 (CAS)
PPi	Metabolite	18361 (ChEBI)
Peptide Chain Release Factor 1	GeneProduct	4809015 (Entrez Gene)	Cthe 2593
PfkB	GeneProduct	4808466 (Entrez Gene)	Cthe 0389,
Phosphoenolpyruvate Carboxykinase	Protein	4809154 (Entrez Gene)	Cthe 2874
Phosphoenolpyruvate Synthase	Protein	4809758 (Entrez Gene)	Cthe 1253
Phosphoglycerare mutase	GeneProduct	4810325 (Entrez Gene)	Cthe 707
Phosphoglycerate kinase	GeneProduct	4808696 (Entrez Gene)	Cthe 0138
Phosphoglycerate mutase	GeneProduct	4809544 (Entrez Gene)	Cthe 1292
Phosphoglycerate mutase	GeneProduct	4811239 (Entrez Gene)	Cthe 0946
Phosphoglyceromutase	GeneProduct	4808698 (Entrez Gene)	Cthe 0140
Pi	Metabolite	14265-44-2 (CAS)
Pii	Metabolite	14265-44-2 (CAS)
Pyruvate formate-lyase activating enzyme	GeneProduct	4808306 (Entrez Gene)	Cthe 0505, Pyruvate formate-lyase activating enzyme
Pyruvate	Metabolite	127-17-3 (CAS)
Pyruvate:fd Oxidoreductase δ	GeneProduct	4811043 (Entrez Gene)	Cthe 2392
Pyruvate:fd Oxioreductase ɤ	GeneProduct	4811042 (Entrez Gene)	Cthe 2390
Pyruvate:fd Oxioreductase α	GeneProduct	4811044 (Entrez Gene)	Cthe 2392
Pyruvate:fl/fd Oxioreductase-Like	GeneProduct	4809683 (Entrez Gene)	Cthe 3120, pyruvate flavodoxin/ferredoxin oxidoreductase-like protein
Pyruvate:fl/fd Oxioreductase-like	GeneProduct	4810484 (Entrez Gene)	Cthe 0866, pyruvate flavodoxin/ferredoxin oxidoreductase-like protein
Ribose 5-phosphate	Metabolite	4300-28-1 (CAS)
Ribose-5-P Isomerase	GeneProduct	4809019 (Entrez Gene)	Cthe 0576
Ribulose 5-Phosphate	Metabolite	4151-19-3 (CAS)
RnfABCDGE subunit B	GeneProduct	4808151 (Entrez Gene)	Cthe 2435, RnfABCDGE type electron transport complex subunit B
RnfABCDGE subunit C	GeneProduct	4808146 (Entrez Gene)	Cthe 2430, RnfABCDGE type electron transport complex subunit C
RnfABCDGE subunit G	GeneProduct	4808148 (Entrez Gene)	Cthe 2432, RnfABCDGE type electron transport complex subunit G
Sedoheptulose_7-p	Metabolite	2646-35-7 (CAS)
Transketolase subunit A	Protein	4810698 (Entrez Gene)	Cthe 2704, transketolase subunit A
Transketolase subunit B	Protein	4809823 (Entrez Gene)	Cthe 2444, transketolase subunit B, (Cthe 2443 not detected) C-terminal subunit
Transketolase subunit B	Protein	4810699 (Entrez Gene)	Cthe 2705, transketolase subunit B, C-terminal section
Triosephosphate Isomerase	GeneProduct	4808697 (Entrez Gene)	Cthe 0347
Unannotated Transaldolase	Protein	2.2.1.2 (EC Number)	Cthe 2444, transketolase subunit B, (Cthe 2443 not detected) C-terminal subunit
binding-protein	Protein	4811172 (Entrez Gene)	Cthe 2125, binding-protein-dependent transport systems inner membrane component (permease component) Type your comment here
binding-protein	Protein	4811173 (Entrez Gene)	Cthe 2126, binding-protein-dependent transport systems inner membrane component (permease component)
binding-protein	Protein	4811312 (Entrez Gene)	Cthe 1018, binding-protein-dependent transport systems inner membrane component (sugar ABC transporter, permease protein) Type your comment here
binding-protein	Protein	4811313 (Entrez Gene)	Cthe 1019, binding-protein-dependent transport systems inner membrane component, putative transmembrane sugar transport protein Type your comment here
extracellular solute-binding protein	Protein	4811175 (Entrez Gene)	Cthe 2128 (sugar binding periplasmic protein
extracellular solute-binding protein	Metabolite	4811314 (ChEBI)	Cthe 1020
hydrogenase, Fe-only	GeneProduct	4808358 (Entrez Gene)	Cthe 0430
phosphoenolpyruvate	Metabolite	138-08-9 (CAS)
phosphoglycerate mutase	Protein	4809828 (Entrez Gene)	Location in ABC Transporter not specified.
α-D-glucose 1-phosphate	Metabolite	59-56-3 (CAS)
α-Glucan Phosphorylase	GeneProduct	4808434 (Entrez Gene)	Cthe 0357, alpha-glucan phosphorylases
α-Phosphoglucomutase	GeneProduct	4809770 (Entrez Gene)	Cthe 1265

Annotated Interactions