Pyruvate Reactions (Clostridium thermocellum)
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5
Pyruvate
L-Lactate Dehydrogenase
Lactate
AcetylCoA
phosphoenolpyruvate
AMP-dependent synthetase and ligase
Ethanol
Acetaldhyde Dehydrogenase/Alcohol Dehydrogenase
Formate
Formate acetyltransferase
NADP+
NADP+
NADPH
NADPH
Acetate
ATP
AMP
Oxaloacetic Acid
Phosphoenolpyruvate Carboxykinase
Carboxyl transferase
Biotin/lipoyl attachment protein
Oxaloacetate Decarboxylase
C02
Malate
Malate Dehydrogenase (NAD)
NAD+
NADH
Malate Dehydrogenase
Phosphoenolpyruvate Synthase
Pyruvate formate-lyase activating enzyme
C02
Acetaldehyde
Fe-Containing ADH
Fe-Containing ADH
NADPH
NADP+
Pii
Pyruvate dehydrogenase/Pyruvate Oxidase
Description
No description
Comments
Metabolically deduced pathway of pyruvate catabolism in Clositridium thermocellum ATCC 27405.
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Revision
Action
Time
User
Comment
50512
view
19:38, 16 August 2012
MaintBot
Deleted pathway: request by author; she plans to resubmit after publication
47678
view
19:20, 2 April 2012
Bjorklund
Modified description
47663
view
18:35, 2 April 2012
Bjorklund
Modified description
47661
view
18:12, 2 April 2012
Bjorklund
Modified description
47660
view
18:10, 2 April 2012
Bjorklund
Modified title
47659
view
18:07, 2 April 2012
Bjorklund
New pathway
External references
DataNodes
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Name
Type
Database reference
Comment
AMP-dependent synthetase and ligase
Protein
19926-71-7 (CAS)
Cthe 0551, Acetate Thiokinase
AMP
Metabolite
61-19-8 (CAS)
ATP
Metabolite
56-65-5 (ChEBI)
Acetaldehyde
Metabolite
75-07-0 (CAS)
Acetaldhyde Dehydrogenase/Alcohol Dehydrogenase
GeneProduct
4808426 (Entrez Gene)
Cthe 0423
Acetate
Metabolite
758-12-3 (CAS)
AcetylCoA
Metabolite
72-89-9 (CAS)
Biotin/lipoyl attachment protein
Protein
4810318 (Entrez Gene)
Cthe 0700
C02
Metabolite
124-38-9 (CAS)
Carboxyl transferase
Protein
4810317 (Entrez Gene)
Cthe 0699
Ethanol
Metabolite
64-17-5 (CAS)
Fe-Containing ADH
GeneProduct
4808397 (Entrez Gene)
Cthe 0394, iron-containing alcohol dehydrogenase
Fe-Containing ADH
GeneProduct
4808725 (Entrez Gene)
Cthe 0101, iron-containing alcohol dehydrogenase
Formate acetyltransferase
GeneProduct
4808305 (Entrez Gene)
Cthe 0505, Pyruvate:Formate Lyase (& AE)
Formate
Metabolite
15740 (ChEBI)
L-Lactate Dehydrogenase
GeneProduct
4811351 (Entrez Gene)
Cthe 1053
Lactate
Metabolite
16651 (ChEBI)
Malate Dehydrogenase (NAD)
GeneProduct
4808494 (Entrez Gene)
Cthe 0345
Malate Dehydrogenase
GeneProduct
4808493 (Entrez Gene)
Cthe 0344
Malate
Metabolite
6915-15-7 (CAS)
NAD+
Metabolite
53-54-9 (CAS)
NADH
Metabolite
53-68-4 (CAS)
NADP+
Metabolite
53-59-8 (CAS)
NADPH
Metabolite
53-59-8 (CAS)
Oxaloacetate Decarboxylase
Protein
4810319 (Entrez Gene)
Cthe 0701
Oxaloacetic Acid
Metabolite
328-42-7 (CAS)
Phosphoenolpyruvate Carboxykinase
Protein
4809154 (Entrez Gene)
Cthe 2874
Phosphoenolpyruvate Synthase
Protein
4809758 (Entrez Gene)
Cthe 1253
Pii
Metabolite
14265-44-2 (CAS)
Pyruvate dehydrogenase/Pyruvate Oxidase
Complex
EC 1.2.2.2 (Enzyme Nomenclature)
See Pathway detailed in Pyruvate:Fd Oxidoreductase Complex (Clostridium thermocellum)
Pyruvate formate-lyase activating enzyme
GeneProduct
4808306 (Entrez Gene)
Cthe 0505, Pyruvate formate-lyase activating enzyme
Pyruvate
Metabolite
127-17-3 (CAS)
phosphoenolpyruvate
Metabolite
138-08-9 (CAS)
Annotated Interactions
No annotated interactions
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No annotated interactions