Pyruvate Reactions (Clostridium thermocellum)

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5L-Lactate Dehydrogenase LactatePyruvateAcetylCoAphosphoenolpyruvateAMP-dependent synthetase and ligaseEthanolAcetaldhyde Dehydrogenase/Alcohol DehydrogenaseFormateFormate acetyltransferaseNADP+NADP+NADPHNADPHAcetateATPAMPOxaloacetic AcidPhosphoenolpyruvate CarboxykinaseCarboxyl transferaseBiotin/lipoyl attachment proteinOxaloacetate DecarboxylaseC02MalateMalate Dehydrogenase (NAD) NAD+NADHMalate DehydrogenasePhosphoenolpyruvate Synthase Pyruvate formate-lyase activating enzymeC02AcetaldehydeFe-Containing ADHFe-Containing ADHNADPHNADP+PiiPyruvate dehydrogenase/Pyruvate Oxidase


Description

Metabolically deduced pathway of pyruvate catabolism in Clositridium thermocellum ATCC 27405 except for details of Pyruvate dehydrogenase/Pyruvate Oxidase (EC 1.2.2.2) which is detailed in Pyruvate:Fd Oxidoreductase Complex (Clostridium thermocellum) WP2156. See also: Combined Pathways for Cellulose Digestion (Clostridium thermocellum) WP2105, and also WP2115, WP2173, WP2174

Comments

 
Metabolically deduced pathway of pyruvate catabolism in Clositridium thermocellum ATCC 27405.

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Bibliography


History

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CompareRevisionActionTimeUserComment
50512view19:38, 16 August 2012MaintBotDeleted pathway: request by author; she plans to resubmit after publication
47678view19:20, 2 April 2012BjorklundModified description
47663view18:35, 2 April 2012BjorklundModified description
47661view18:12, 2 April 2012BjorklundModified description
47660view18:10, 2 April 2012BjorklundModified title
47659view18:07, 2 April 2012BjorklundNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AMP-dependent synthetase and ligaseProtein19926-71-7 (CAS) Cthe 0551, Acetate Thiokinase
AMPMetabolite61-19-8 (CAS)
ATPMetabolite56-65-5 (ChEBI)
AcetaldehydeMetabolite75-07-0 (CAS)
Acetaldhyde Dehydrogenase/Alcohol DehydrogenaseGeneProduct4808426 (Entrez Gene) Cthe 0423
AcetateMetabolite758-12-3 (CAS)
AcetylCoAMetabolite72-89-9 (CAS)
Biotin/lipoyl attachment proteinProtein4810318 (Entrez Gene) Cthe 0700
C02Metabolite124-38-9 (CAS)
Carboxyl transferaseProtein4810317 (Entrez Gene) Cthe 0699
EthanolMetabolite64-17-5 (CAS)
Fe-Containing ADHGeneProduct4808397 (Entrez Gene) Cthe 0394, iron-containing alcohol dehydrogenase
Fe-Containing ADHGeneProduct4808725 (Entrez Gene) Cthe 0101, iron-containing alcohol dehydrogenase
Formate acetyltransferaseGeneProduct4808305 (Entrez Gene) Cthe 0505, Pyruvate:Formate Lyase (& AE)
FormateMetabolite15740 (ChEBI)
L-Lactate Dehydrogenase GeneProduct4811351 (Entrez Gene) Cthe 1053
LactateMetabolite16651 (ChEBI)
Malate Dehydrogenase (NAD) GeneProduct4808494 (Entrez Gene) Cthe 0345
Malate DehydrogenaseGeneProduct4808493 (Entrez Gene) Cthe 0344
MalateMetabolite6915-15-7 (CAS)
NAD+Metabolite53-54-9 (CAS)
NADHMetabolite53-68-4 (CAS)
NADP+Metabolite53-59-8 (CAS)
NADPHMetabolite53-59-8 (CAS)
Oxaloacetate DecarboxylaseProtein4810319 (Entrez Gene) Cthe 0701
Oxaloacetic AcidMetabolite328-42-7 (CAS)
Phosphoenolpyruvate CarboxykinaseProtein4809154 (Entrez Gene) Cthe 2874
Phosphoenolpyruvate Synthase Protein4809758 (Entrez Gene) Cthe 1253
PiiMetabolite14265-44-2 (CAS)
Pyruvate dehydrogenase/Pyruvate Oxidase ComplexEC 1.2.2.2 (Enzyme Nomenclature) See Pathway detailed in Pyruvate:Fd Oxidoreductase Complex (Clostridium thermocellum)
Pyruvate formate-lyase activating enzymeGeneProduct4808306 (Entrez Gene) Cthe 0505, Pyruvate formate-lyase activating enzyme
PyruvateMetabolite127-17-3 (CAS)
phosphoenolpyruvateMetabolite138-08-9 (CAS)

Annotated Interactions

No annotated interactions
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