Tissue fate map (Homo sapiens)

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MesodermMidbrainSubstantia NigraCytotrophoblastSpinal CordOmental AdiposeFrontal CortexVisceral PeritoneumStomach CardiacCD8+Lymph NodesPathwayKidney CortexEndocardiumCerebellar VermisOuter Layers of EyeVisceral PleuraLateral MesodermNeural Stem CellsCD34+Digestive TubeStroma of GonadsDorsal Root GangliaParathyroidsFetal PancreasMesenchymeT CellsPrimitive GutEye LensHypophysis Anteriror LobeMesonephric DuctsBlood CorpusclesOvariesGlutamatergic ProgenitorNK CellsEpicardiumAxial SkeletonJoint Tissue SynoviumSkull and Branchial CartilagesTracheaSpinal Dorsal Root GangliaKeratinocytesEndometriumHead MesenchymeHead MusclesFetal Small IntestineVentral Tegmental AreaBrainFetal HeartPlacentaGranulocytesUrethraProstate GlandOral EpitheliumLeg MuscleAllantoisPituitary GlandFetal BrainGloubus Pallidum InternalSynovial MembraneCerebellar HemisphereMedullaStomach PyloricAnal CanalHindbrainMullerian DuctsVulvaEpididymisPleuraFetal KidneyAuditory VescicleItermediate MesodermB CellsAccumbensThyroidSkinMicrogliaHairProstateCerebellumPonsTonsillar RecessesCoronary ArteryThalamusRetrocervical InfiltrateCervixJejunumFetal Arm MuscleDermatomesEpimyocardiumArm MuscleHippocampusParietal LobePluripotent Stem CellsTongueBlood VesselsMyotubeZygoteHemangioblast TissueCranial Sensory Ganglia and NervesHematopoietic ProgenitorMyoblastSomatic MesodermFallopian TubeAtriumFetal LungsSensory Sinal Nerve RootsPharyngeal PouchesLungsTemporal LobeOuter Epithelium of BodyDuodenumMedulla of AdrenalMammary GlandsAppendecular SkeletonLymphoid ProgentiorMesentariesSyncytiotrophoblastStomodaeal EpitheliumLiverFetal ThyroidPenisDorsal-Paraxial MesodermTrigeminal GangliaAortaNasal-Olfactory EpitheliumCholinergic ProgenitorSaphenous VeinSubthalamic NucleusHeartTestesFetal Large IntestineCerebral CortexVestibular Nuclei SuperiorSpleenSubstantia Nigra ReticulataThalamus Subthalamic NucleusAmygdalaNailsSweat GlandsMesendodermNeural Crest Mesenchymal Stem CellsTongue Main CorpusPharyngeal MucosaFetal Adrenal CortexBronchiAdipose TissueAstrocyte ProgenitorCD4+NippleVaginaThalamus Lateral NucleiTongue Superior With PapillaeErythroblast ProgenitorPericardiumOviductsDopaminergic ProgenitorStomach FundusCaudateSmooth Muscle CellsEsophagusGlobus PallidusHypothalamusScleroteomesVisceraHemangioblastic Stem CellsSmall IntestineBlastocystColonOligodendrocyte ProgenitorAppendage MusclesNeural TubeRetinaTonsilForebrainMyeloid ProgenitorOsteoblastsPutamenDentin of TeethMyometriumMiddle earEndothelium of Blood VesselsBreastGlial CellsEndothelial CellsSebacious GlandsFetal Spinal CordThymusFetal Leg MuscleBone MarrowMyotomesFetal LiverPars Neuralis of HypophysisOccipital LobeUrinary BladderPeritoneumGABAergic ProgenitorMesoderm ProgenitorConnective TissueSplanchnic MesodermCorpus CallosumEarly Endoderm ProgenitorKidneyEctoderm ProgenitorPancreasPharynxMorulaAdipocyte ProgenitorLarge IntestineSubstantia Nigra Pars CompactaTeeth EnamelChondrocytesMyocardiumKidney MedullaVentricleTrophoectodermSubcutaneous AdiposeMonocytesFetal ThymusVentral MesodermVas DeferensOral MucosaConnective Tissue Layers of SkinCephalic Connective tissueGloubus Pallidum ExternalUterusSympathetic GangliaCrainial Motor NervesStomachFrontal LobeNeural ProgenitorSchwann Cell ProgenitorCortexVena CavaSerotonergic ProgenitorSubcorticalPrefrontal CortexDeltoid MuscleDorsolateral Prefrontal NeocortexMedial Prefrontal NeocortexOrbital Prefrontal NeocortexBloodSchwann CellsDopaminergicOligodendrocytesSerotonergicAstrocytesGABAergicGlutamatergicCholinergicErythrocytesVentrolateral Prefrontal NeocortexStriatum Putamen and Caudate NucleusParietal Association NeocortexOccipital Visual NeocortexTemporal Auditory NeocortexTemporal Association CortexMediodorsal ThalamusInduced Pluripotent Stem CellsFetal Kidney Renal CortexFetal Kidney Renal PelvisAdipocytesAorta Smooth Muscle CellsHepatoblastsAdrenal CortexEndodermCardiac ProgenitorCardiomyocytesSkeletal MuscleFetal Skeletal MuscleNeural CrestNeural Crest Stem CellsMelanocyteMotor Somatosensory NeocortexBone Marrow Stem CellsBone Marrow Mesenchymal Stem CellsChorionEpithelial CellsEmbryonic FibroblastsMiddle First TrimesterLate First TrimesterSecond TrimesterLeft AtriumRight AtriumLeft VentricleRight VentricleIslet CellsThymocytesMuscleEarly First TrimesterBone Marrow Hematopoietic ProgenitorsPerivascular AdiposeWhite AdiposeBrown AdiposeEpididymal AdiposeCD19+CD71+Liver Hematopoietic Stem CellsVisual CortexThymocytePartially Reprogrammed iPS CellsFibroblastsCardiac Fibroblast ProgenitorCardiac FibroblastsHepatocytesPrimordial Germ CellsSpermatogonial Stem CellsOocytesMacrophagesTrophoectoderm Stem CellsCD14+MegakaryocyteOptic NervePhotoreceptor CellsRetina Inner Nuclear CellsRetina Inner Plexiform CellsRetina Ganglion CellsDermal Stem CellDermal ProgenitorColon CecumSalivary GlandMesenchymal Stem CellsEmbryoEndoderm ProgenitorEctodermEndodermFetusAdrenal GlandBoneNodose Nucleus


Description

Proposed lineage fate map focusing on (1) adult tissues, (2) fetal tissues, (3) terminally differentiated cells, (5) stem cells and (4) progenitor cells. This pathway is currently in progress but will ultimately be a hub to tissue and cell type specific pathways (nodes converted to pathway nodes).

How to Use

This network is most useful when viewed in Cytoscape with corresponding cell/tissue association data. To use, simply save the GPML and open in Cytoscape (File > Import > Network (Multiple File Types)...) and change the visual style of the pathway to one of the default options under VizMapper > Current Visual Style or load this specific VisualStyle: http://altanalyze.org/TissueFateMap-VizMapperProperty.props. To visualize tissue/cell association data, load an attribute file with corresponding tissue/cell names (e.g., from AltAnalyze's TissueMapper software) using File > Import > Node Attributes (mapping the tissue column to CanonicalName) and set your coloring parameters from VizMapper > Node Color.

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
127710view20:44, 24 November 2023EweitzStandardize case, fix typos
116656view11:46, 9 May 2021EweitzModified title
87775view11:06, 25 July 2016MirellaKalafatiOntology Term : 'regulatory pathway' added !
62399view02:51, 28 April 2013MaintBotCleaned up remaining xref errors
62398view02:48, 28 April 2013MaintBotRemoved datasource from empty xrefs
62397view02:47, 28 April 2013MaintBotUpdating GPML version
57682view20:50, 31 January 2013KhanspersModified categories
54699view12:45, 7 December 2012Andra
54698view12:37, 7 December 2012AndraRDFTidy
47899view19:14, 17 April 2012NsalomonisSpecify description
47898view19:14, 17 April 2012NsalomonisSpecify description
47897view19:11, 17 April 2012NsalomonisSpecify description
47896view18:57, 17 April 2012NsalomonisSpecify description
47895view18:50, 17 April 2012NsalomonisSpecify description
47894view18:47, 17 April 2012NsalomonisSpecify description
47893view18:44, 17 April 2012NsalomonisPeriodical save, work in progress
47892view18:33, 17 April 2012NsalomonisPeriodical save, work in progress
47891view18:29, 17 April 2012NsalomonisSpecify description
47890view18:23, 17 April 2012NsalomonisPeriodical save, work in progress
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47887view17:35, 17 April 2012NsalomonisSpecify description
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47868view06:59, 16 April 2012NsalomonisSpecify description
47867view06:55, 16 April 2012NsalomonisSpecify description
47866view06:49, 16 April 2012NsalomonisPeriodical save, work in progress
47865view06:43, 16 April 2012NsalomonisSpecify description
47864view06:31, 16 April 2012NsalomonisPeriodical save, work in progress
47863view06:21, 16 April 2012NsalomonisPeriodical save, work in progress
47862view06:11, 16 April 2012NsalomonisPeriodical save, work in progress
47861view06:04, 16 April 2012Nsalomonislayout
47858view19:23, 15 April 2012NsalomonisSpecify description
47857view17:41, 15 April 2012NsalomonisPeriodical save, work in progress
45929view00:10, 29 November 2011NsalomonisModified description
45928view00:10, 29 November 2011NsalomonisModified description
45927view00:09, 29 November 2011NsalomonisModified description
45926view00:08, 29 November 2011NsalomonisModified description
45925view00:08, 29 November 2011NsalomonisModified description
45924view00:07, 29 November 2011NsalomonisModified description
45917view21:21, 27 November 2011NsalomonisSpecify description
45845view16:03, 17 November 2011NsalomonisSpecify description
45776view04:29, 9 November 2011NsalomonisSpecify description
45767view01:33, 7 November 2011NsalomonisSpecify description
45740view21:15, 3 November 2011NsalomonisSpecify description
45731view00:42, 3 November 2011NsalomonisSpecify description
45730view23:53, 2 November 2011NsalomonisSpecify description
45729view23:40, 2 November 2011NsalomonisSpecify description
45728view23:33, 2 November 2011NsalomonisSpecify description
45727view23:28, 2 November 2011NsalomonisSpecify description
45723view19:14, 2 November 2011NsalomonisSpecify description

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Accumbens
Adipocyte Progenitor
Adipocytes
Adipose Tissue
Adrenal Cortex
Adrenal Gland
Allantois
Amygdala
Anal Canal
Aorta Smooth Muscle Cells
Aorta
Appendage Muscles
Appendecular Skeleton
Arm Muscle
Astrocyte Progenitor
Astrocytes
Atrium
Auditory Vescicle
Axial Skeleton
B Cells
BlastocystBlastocyst (Uniprot/TrEMBL)
Blood Corpuscles
Blood Vessels
Blood
Bone Marrow Hematopoietic Progenitors
Bone Marrow Mesenchymal Stem Cells
Bone Marrow Stem Cells
Bone Marrow
Bone
Brain
Breast
Bronchi
Brown Adipose
CD14+
CD19+
CD34+
CD4+
CD71+
CD8+
Cardiac Fibroblast Progenitor
Cardiac Fibroblasts
Cardiac Progenitor
Cardiomyocytes
Caudate
Cephalic Connective tissue
Cerebellar Hemisphere
Cerebellar Vermis
Cerebellum
Cerebral Cortex
Cervix
Cholinergic Progenitor
Cholinergic
Chondrocytes
ChorionChorion (Uniprot/TrEMBL)
Colon Cecum
Colon
Connective Tissue Layers of Skin
Connective Tissue
Coronary Artery
Corpus Callosum
Cortex
Crainial Motor Nerves
Cranial Sensory Ganglia and Nerves
CytotrophoblastCytotrophoblast (Uniprot/TrEMBL)
Deltoid Muscle
Dentin of Teeth
Dermal Progenitor
Dermal Stem Cell
Dermatomes
Digestive Tube
Dopaminergic Progenitor
Dopaminergic
Dorsal Root Ganglia
Dorsal-Paraxial Mesoderm
Dorsolateral Prefrontal Neocortex
Duodenum
Early Endoderm ProgenitorEarly Endoderm Progenitor (Uniprot/TrEMBL)
Early First TrimesterEarly First Trimester (Uniprot/TrEMBL)
Ectoderm ProgenitorEctoderm Progenitor (Uniprot/TrEMBL)
EmbryoEmbryo (Uniprot/TrEMBL)
Embryonic Fibroblasts
Endocardium
Endoderm ProgenitorEndoderm Progenitor (Uniprot/TrEMBL)
EndodermEndoderm (Uniprot/TrEMBL)
Endometrium
Endothelial Cells
Endothelium of Blood Vessels
Epicardium
Epididymal Adipose
Epididymis
Epimyocardium
Epithelial Cells
Erythroblast Progenitor
Erythrocytes
Esophagus
Eye Lens
Fallopian Tube
Fetal Adrenal Cortex
Fetal Arm Muscle
Fetal Brain
Fetal Heart
Fetal Kidney Renal Cortex
Fetal Kidney Renal Pelvis
Fetal Kidney
Fetal Large Intestine
Fetal Leg Muscle
Fetal Liver
Fetal Lungs
Fetal Pancreas
Fetal Skeletal Muscle
Fetal Small Intestine
Fetal Spinal CordFetal Spinal Cord (Uniprot/TrEMBL)
Fetal Thymus
Fetal Thyroid
FetusFetus (Uniprot/TrEMBL)
Fibroblasts
Forebrain
Frontal Cortex
Frontal Lobe
GABAergic Progenitor
GABAergic
Glial Cells
Globus Pallidus
Gloubus Pallidum External
Gloubus Pallidum Internal
Glutamatergic Progenitor
Glutamatergic
Granulocytes
Hair
Head Mesenchyme
Head Muscles
Heart
Hemangioblast Tissue
Hemangioblastic Stem Cells
Hematopoietic Progenitor
Hepatoblasts
Hepatocytes
Hindbrain
Hippocampus
Hypophysis Anteriror Lobe
Hypothalamus
Induced Pluripotent Stem CellsInduced Pluripotent Stem Cells (Uniprot/TrEMBL)
Islet Cells
Itermediate Mesoderm
Jejunum
Joint Tissue Synovium
Keratinocytes
Kidney Cortex
Kidney Medulla
Kidney
Large Intestine
Late First TrimesterLate First Trimester (Uniprot/TrEMBL)
Lateral Mesoderm
Left Atrium
Left Ventricle
Leg Muscle
Liver Hematopoietic Stem Cells
Liver
Lungs
Lymph Nodes
Lymphoid Progentior
Macrophages
Mammary Glands
Medial Prefrontal Neocortex
Mediodorsal Thalamus
Medulla of Adrenal
Medulla
Megakaryocyte
Melanocyte
Mesenchymal Stem Cells
Mesenchyme
MesendodermMesendoderm (Uniprot/TrEMBL)
Mesentaries
Mesoderm ProgenitorMesoderm Progenitor (Uniprot/TrEMBL)
Mesonephric Ducts
Microglia
Midbrain
Middle First TrimesterMiddle First Trimester (Uniprot/TrEMBL)
Middle ear
Monocytes
MorulaMorula (Uniprot/TrEMBL)
Motor Somatosensory Neocortex
Mullerian Ducts
Muscle
Myeloid Progenitor
Myoblast
Myocardium
Myometrium
Myotomes
Myotube
NK Cells
Nails
Nasal-Olfactory Epithelium
Neural Crest Mesenchymal Stem Cells
Neural Crest Stem Cells
Neural Crest
Neural Progenitor
Neural Stem Cells
Neural Tube
Nipple
Nodose Nucleus
Occipital Lobe
Occipital Visual Neocortex
Oligodendrocyte Progenitor
Oligodendrocytes
Omental Adipose
Oocytes
Optic Nerve
Oral Epithelium
Oral Mucosa
Orbital Prefrontal Neocortex
Osteoblasts
Outer Epithelium of Body
Outer Layers of Eye
Ovaries
Oviducts
Pancreas
Parathyroids
Parietal Association Neocortex
Parietal Lobe
Pars Neuralis of Hypophysis
Partially Reprogrammed iPS CellsPartially Reprogrammed iPS Cells (Uniprot/TrEMBL)
Pathway
Penis
Pericardium
Peritoneum
Perivascular Adipose
Pharyngeal Mucosa
Pharyngeal Pouches
Pharynx
Photoreceptor Cells
Pituitary Gland
Placenta
Pleura
Pluripotent Stem CellsPluripotent Stem Cells (Uniprot/TrEMBL)
Pons
Prefrontal Cortex
Primitive Gut
Primordial Germ Cells
Prostate Gland
Prostate
Putamen
Retina Ganglion Cells
Retina Inner Nuclear Cells
Retina Inner Plexiform Cells
Retina
Retrocervical Infiltrate
Right Atrium
Right Ventricle
Salivary Gland
Saphenous Vein
Schwann Cell Progenitor
Schwann Cells
Scleroteomes
Sebacious Glands
Second TrimesterSecond Trimester (Uniprot/TrEMBL)
Sensory Sinal Nerve Roots
Serotonergic Progenitor
Serotonergic
Skeletal Muscle
Skin
Skull and Branchial Cartilages
Small Intestine
Smooth Muscle Cells
Somatic Mesoderm
Spermatogonial Stem Cells
Spinal Cord
Spinal Dorsal Root Ganglia
Splanchnic Mesoderm
Spleen
Stomach Cardiac
Stomach Fundus
Stomach Pyloric
Stomach
Stomodaeal Epithelium
Striatum Putamen and Caudate Nucleus
Stroma of Gonads
Subcortical
Subcutaneous Adipose
Substantia Nigra Pars Compacta
Substantia Nigra Reticulata
Substantia Nigra
Subthalamic Nucleus
Sweat Glands
Sympathetic Ganglia
SyncytiotrophoblastSyncytiotrophoblast (Uniprot/TrEMBL)
Synovial Membrane
T Cells
Teeth Enamel
Temporal Association Cortex
Temporal Auditory Neocortex
Temporal Lobe
Testes
Thalamus Lateral Nuclei
Thalamus Subthalamic Nucleus
Thalamus
Thymocyte
Thymocytes
Thymus
Thyroid
Tongue Main Corpus
Tongue Superior With Papillae
Tongue
Tonsil
Tonsillar Recesses
Trachea
Trigeminal Ganglia
Trophoectoderm Stem CellsTrophoectoderm Stem Cells (Uniprot/TrEMBL)
TrophoectodermTrophoectoderm (Uniprot/TrEMBL)
Urethra
Urinary Bladder
Uterus
Vagina
Vas Deferens
Vena Cava
Ventral Mesoderm
Ventral Tegmental Area
Ventricle
Ventrolateral Prefrontal Neocortex
Vestibular Nuclei Superior
Viscera
Visceral Peritoneum
Visceral Pleura
Visual Cortex
Vulva
White Adipose
ZygoteZygote (Uniprot/TrEMBL)

Annotated Interactions

No annotated interactions

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