Regulation of actin cytoskeleton (Pan troglodytes)
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GF
Actomyosin
assembly contraction
Chemotatic factor
RTK
Filipodia
Stabilization
of actin
RAS
Focal complex
assembly
-p
Actin
polymerization
Growth Factor (GF)
RTK
RAS
Focal adhesion
assembly
Lamellipodia
stress fiber
GPCR
PI3K
GPCR
Chemotactic factor
Actin polymerization
PI3K
Gene Expression
+p
Actin polymerization
stress fiber
RAC3
BDKRB2
CHRM4
PIK3R1
VCL
ARHGEF4
FGF18
CSK
RAF1
FGF17
GIT1
PIK3CB
FGFR1
VIL1
ARHGEF7
ACTB
PDGFB
FGF16
Focal Adhesion
pathway
FGF4
FGFR4
FGF10
FGF3
ACTG1
ITGA1
ACTN1
F2R
SSH2
PIK3C2A
PIK3R2
FGFR2
FGF9
EGF
Bradykinin
FGF6
RRAS2
Apc2
PIK3CA
DIAP3
SOS2
Adherens junction
pathway
CD14
MYLK
EGFR
FGF12
CHRM1
PIP2
PIK3C3
RRAS
LOC748477
LOC460327
PIK3R5
PIP4K2C
CHRM2
LOC465655
FGF8
LOC470938
ACTB
MAPK6
ABI2
SSH3
ACTB
FGF21
LOC456157
ROCK1
PIK3C2G
BRAF
ARHGEF6
FGF13
MAPK Signaling
pathway
PIK3CG
MSN
CFL2
FGF22
PIP4K2A
ROCK2
CDC42
PIP5K1A
LOC100609242
PIP4K2A
PIK3C2B
FGF23
RDX
NCKAP1
Acetylcholine
PAK2
MYH10
FGF20
BCAR1
RASSF7
FGF1
MYL1
ACTG1
LIMK1
INS2
PDGFRA
MAPK3
FGFR3
LOC741907
LPS
NRAS
FGF5
GNA13
RAC1P4
PIP5K1C
ENAH
PIP5K1B
PTK2
CHRM5
SSH1
FGF2
CHRM3
MAPK1
LOC748477
VAV1
PAK6
FGF14
FN1
VCL
ARHGEF6
MOS
DIAP1
PIP5KL1
LOC100611792
PIK3R4
CFL1
FGF15
EZR
PXN
INS1
ARPC5
APC
WAS
BAIAP2
CRK
ARHGEF1
PIP4K2B
TMSB4X
RAC2
PAK3
PIP2
PAK7
ARPC5
PIP3
PDGFRB
BDKRB1
IQGAP1
BAIAP2
GNA12
WASF2
SOS1
RHOA
DOCK1
WASF1
PIK3CD
ACTG1
PAK1
C3orf10
FGF11
GSN
PAK4
SLC9A1
PDGFA
PPP1R12A
Focal Adhesion
pathway
KRAS
PIK3R3
FGF7
CYFIP2
F2
MAP2K1
LOC442775
LOC468536
Description
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP51(r45278)
with a 80% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
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Bibliography
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History
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Revision
Action
Time
User
Comment
128551
view
04:35, 12 February 2024
Eweitz
Modified title
114262
view
13:59, 2 January 2021
Egonw
Three more pathways clickable
72131
view
07:57, 25 October 2013
Mkutmon
added datasource to pathway datanodes
71673
view
19:41, 17 October 2013
MaintBot
Automated update of data sources
69266
view
18:38, 8 July 2013
MaintBot
Updated to 2013 gpml schema
48143
view
18:34, 9 May 2012
MaintBot
Updating from human to fix xrefs
41574
view
02:00, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34302
view
22:05, 9 December 2009
MaintBot
Automatic update of empty xrefs
33594
view
09:54, 1 December 2009
MaintBot
Removed group label
31614
view
22:15, 13 August 2009
MaintBot
Fixed text labels
30513
view
21:46, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ABI2
GeneProduct
459892 (Entrez Gene)
ACTB
GeneProduct
450133 (Entrez Gene)
ACTG1
GeneProduct
ACTN1
GeneProduct
452993 (Entrez Gene)
APC
GeneProduct
461999 (Entrez Gene)
ARHGEF1
GeneProduct
ARHGEF4
GeneProduct
470538 (Entrez Gene)
ARHGEF6
GeneProduct
ARHGEF7
GeneProduct
452673 (Entrez Gene)
ARPC5
GeneProduct
457574 (Entrez Gene)
Acetylcholine
Metabolite
51-84-3 (CAS)
Adherens junction pathway
Pathway
Apc2
GeneProduct
BAIAP2
GeneProduct
454951 (Entrez Gene)
BCAR1
GeneProduct
454246 (Entrez Gene)
BDKRB1
GeneProduct
100612769 (Entrez Gene)
BDKRB2
GeneProduct
467547 (Entrez Gene)
BRAF
GeneProduct
463781 (Entrez Gene)
Bradykinin
Metabolite
58-82-2 (CAS)
C3orf10
GeneProduct
CD14
GeneProduct
462118 (Entrez Gene)
CDC42
GeneProduct
CFL1
GeneProduct
745772 (Entrez Gene)
CFL2
GeneProduct
452853 (Entrez Gene)
CHRM1
GeneProduct
451272 (Entrez Gene)
CHRM2
GeneProduct
463758 (Entrez Gene)
CHRM3
GeneProduct
469725 (Entrez Gene)
CHRM4
GeneProduct
CHRM5
GeneProduct
503515 (Entrez Gene)
CRK
GeneProduct
747142 (Entrez Gene)
CSK
GeneProduct
453745 (Entrez Gene)
CYFIP2
GeneProduct
462221 (Entrez Gene)
DIAP1
GeneProduct
DIAP3
GeneProduct
DOCK1
GeneProduct
EGF
GeneProduct
461435 (Entrez Gene)
EGFR
GeneProduct
463415 (Entrez Gene)
ENAH
GeneProduct
EZR
GeneProduct
463100 (Entrez Gene)
F2
GeneProduct
451158 (Entrez Gene)
F2R
GeneProduct
471510 (Entrez Gene)
FGF10
GeneProduct
471553 (Entrez Gene)
FGF11
GeneProduct
748965 (Entrez Gene)
FGF12
GeneProduct
471041 (Entrez Gene)
FGF13
GeneProduct
465886 (Entrez Gene)
FGF1
GeneProduct
462158 (Entrez Gene)
FGF14
GeneProduct
739338 (Entrez Gene)
FGF15
GeneProduct
FGF16
GeneProduct
473676 (Entrez Gene)
FGF17
GeneProduct
472708 (Entrez Gene)
FGF18
GeneProduct
FGF20
GeneProduct
739665 (Entrez Gene)
FGF21
GeneProduct
468948 (Entrez Gene)
FGF22
GeneProduct
FGF23
GeneProduct
747164 (Entrez Gene)
FGF2
GeneProduct
641462 (Entrez Gene)
FGF3
GeneProduct
466693 (Entrez Gene)
FGF4
GeneProduct
747727 (Entrez Gene)
FGF5
GeneProduct
471190 (Entrez Gene)
FGF6
GeneProduct
747181 (Entrez Gene)
FGF7
GeneProduct
744975 (Entrez Gene)
FGF8
GeneProduct
FGF9
GeneProduct
744731 (Entrez Gene)
FGFR1
GeneProduct
464122 (Entrez Gene)
FGFR2
GeneProduct
466220 (Entrez Gene)
FGFR3
GeneProduct
461067 (Entrez Gene)
FGFR4
GeneProduct
462301 (Entrez Gene)
FN1
GeneProduct
459926 (Entrez Gene)
Focal Adhesion pathway
Pathway
WP306
GIT1
GeneProduct
454549 (Entrez Gene)
GNA12
GeneProduct
463234 (Entrez Gene)
GNA13
GeneProduct
454827 (Entrez Gene)
GSN
GeneProduct
464706 (Entrez Gene)
INS1
GeneProduct
INS2
GeneProduct
IQGAP1
GeneProduct
467762 (Entrez Gene)
ITGA1
GeneProduct
461880 (Entrez Gene)
KRAS
GeneProduct
473387 (Entrez Gene)
LIMK1
GeneProduct
463466 (Entrez Gene)
LOC100609242
GeneProduct
100609242 (Entrez Gene)
LOC100611792
GeneProduct
100611792 (Entrez Gene)
LOC442775
GeneProduct
LOC456157
GeneProduct
456157 (Entrez Gene)
LOC460327
GeneProduct
460327 (Entrez Gene)
LOC465655
GeneProduct
465655 (Entrez Gene)
LOC468536
GeneProduct
468536 (Entrez Gene)
LOC470938
GeneProduct
470938 (Entrez Gene)
LOC741907
GeneProduct
741907 (Entrez Gene)
LOC748477
GeneProduct
748477 (Entrez Gene)
LPS
Metabolite
C00338 (Kegg Compound)
MAP2K1
GeneProduct
450188 (Entrez Gene)
MAPK Signaling pathway
Pathway
WP382
MAPK1
GeneProduct
458680 (Entrez Gene)
MAPK3
GeneProduct
454037 (Entrez Gene)
MAPK6
GeneProduct
453439 (Entrez Gene)
MOS
GeneProduct
472772 (Entrez Gene)
MSN
GeneProduct
MYH10
GeneProduct
455090 (Entrez Gene)
MYL1
GeneProduct
459915 (Entrez Gene)
MYLK
GeneProduct
460640 (Entrez Gene)
NCKAP1
GeneProduct
459801 (Entrez Gene)
NRAS
GeneProduct
742713 (Entrez Gene)
PAK1
GeneProduct
451439 (Entrez Gene)
PAK2
GeneProduct
460965 (Entrez Gene)
PAK3
GeneProduct
450118 (Entrez Gene)
PAK4
GeneProduct
PAK6
GeneProduct
453327 (Entrez Gene)
PAK7
GeneProduct
469876 (Entrez Gene)
PDGFA
GeneProduct
PDGFB
GeneProduct
458844 (Entrez Gene)
PDGFRA
GeneProduct
PDGFRB
GeneProduct
462188 (Entrez Gene)
PIK3C2A
GeneProduct
451052 (Entrez Gene)
PIK3C2B
GeneProduct
457657 (Entrez Gene)
PIK3C2G
GeneProduct
PIK3C3
GeneProduct
455385 (Entrez Gene)
PIK3CA
GeneProduct
460858 (Entrez Gene)
PIK3CB
GeneProduct
PIK3CD
GeneProduct
457922 (Entrez Gene)
PIK3CG
GeneProduct
463649 (Entrez Gene)
PIK3R1
GeneProduct
461836 (Entrez Gene)
PIK3R2
GeneProduct
455855 (Entrez Gene)
PIK3R3
GeneProduct
456565 (Entrez Gene)
PIK3R4
GeneProduct
460692 (Entrez Gene)
PIK3R5
GeneProduct
455085 (Entrez Gene)
PIP2
Metabolite
C04637 (Kegg Compound)
PIP3
Metabolite
C05981 (Kegg Compound)
PIP4K2A
GeneProduct
742458 (Entrez Gene)
PIP4K2B
GeneProduct
746830 (Entrez Gene)
PIP4K2C
GeneProduct
467044 (Entrez Gene)
PIP5K1A
GeneProduct
457288 (Entrez Gene)
PIP5K1B
GeneProduct
464513 (Entrez Gene)
PIP5K1C
GeneProduct
455590 (Entrez Gene)
PIP5KL1
GeneProduct
464758 (Entrez Gene)
PPP1R12A
GeneProduct
452095 (Entrez Gene)
PTK2
GeneProduct
464422 (Entrez Gene)
PXN
GeneProduct
452303 (Entrez Gene)
RAC1P4
GeneProduct
RAC2
GeneProduct
RAC3
GeneProduct
RAF1
GeneProduct
460182 (Entrez Gene)
RASSF7
GeneProduct
466303 (Entrez Gene)
RDX
GeneProduct
466776 (Entrez Gene)
RHOA
GeneProduct
461014 (Entrez Gene)
ROCK1
GeneProduct
455326 (Entrez Gene)
ROCK2
GeneProduct
470307 (Entrez Gene)
RRAS2
GeneProduct
451038 (Entrez Gene)
RRAS
GeneProduct
468955 (Entrez Gene)
SLC9A1
GeneProduct
456669 (Entrez Gene)
SOS1
GeneProduct
459171 (Entrez Gene)
SOS2
GeneProduct
452897 (Entrez Gene)
SSH1
GeneProduct
467124 (Entrez Gene)
SSH2
GeneProduct
454551 (Entrez Gene)
SSH3
GeneProduct
451365 (Entrez Gene)
TMSB4X
GeneProduct
VAV1
GeneProduct
455647 (Entrez Gene)
VCL
GeneProduct
450531 (Entrez Gene)
VIL1
GeneProduct
470646 (Entrez Gene)
WAS
GeneProduct
WASF1
GeneProduct
462935 (Entrez Gene)
WASF2
GeneProduct
456675 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Discussion
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View approved pathways at the new wikipathways.org.Quality Tags
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Bibliography
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History
External references
DataNodes
Annotated Interactions
No annotated interactions