Glucocorticoid metabolism (Rattus norvegicus)

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COH=OProgesteroneUrocortisol3*17a,21-Dihydroxy-5b-HOHOHOCHOOC*5b-Pregnane-3,20-dioneFrom Cholersterol BiosynthesisSignalingOPregnanediolCortisol=OPregnenoloneHO11-DeoxycortisolCortisone18-Hydroxy-CorticosteroneAldosterone5b-Pregnan-18-alHO17-a-OH-Progesterone5b-Pregnan-18-alCortolone3a,11b,21-Trihydroxy-20-Oxo-OOHGlucocorticoidsCholesterolC3311-Deoxycorticosterone3a-OH-5b-Pregnane-20-one3CortolProgesterone DegradationCOH11b, 21-Dihydroxy-3,20-OHCorticosteroneO=OCHHO=O-OHHPregnane 3,20-dione=OUrocortisone17-a-OH-Pregnenolone2CCHH2CH11b,17a 21-Trihydroxy-5bCHOH2CHand MetabolismCCCHOTo Androgen Synthesis3Steroid HormoneCHCHCGlucuronidesOHOH=O=OPregnane-3,11,20-trioneCyp17a1Cortisone beta-reductaseSteroid delta-IsomeraseCorticosterone 18-Monooxy3-Oxo-5b-Steroid Dh(R)20-hydroxysteroid DhRGD:708361Cyp17a120b-Hydroxysteroid DhCyp21a13B-OH-delta-Steroid DhCyp11a1Steroid delta-IsomeraseCyp11b1RGD:708361Hsd11b13B-OH-delta-Steroid DhHsd11b2


Description

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
116969view10:27, 16 May 2021EweitzModified title
71794view20:33, 17 October 2013MaintBotAutomated update of data sources
71303view16:59, 17 October 2013MaintBotAutomated update of data sources
70648view19:22, 21 August 2013EgonwReduced the number of Labels for each compound name from 2 to 1.
70647view19:16, 21 August 2013EgonwConverted a number of Labels into DataNodes.
69414view19:01, 8 July 2013MaintBotUpdated to 2013 gpml schema
67285view10:31, 26 June 2013Christine ChichesterOntology Term : 'C21-steroid hormone biosynthetic pathway' added !
62849view05:05, 3 May 2013MaintBotUpdated UniProt data source
49013view11:47, 3 July 2012Ishida-kazuyaPeriodical save, work in progress
49010view08:28, 3 July 2012Ishida-kazuya120704_JSOT2
49009view08:26, 3 July 2012Ishida-kazuya120703_JSOT
41736view02:39, 2 March 2011MaintBotRemoved redundant pathway information and comments
21321view11:31, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Glucocorticoid Mineralocorticoid Metabolism]] moved to [[Pathway:WP305]]: Moved to stable identifier
8082view13:46, 7 January 2008MaintBot[[Pathway:Rat:Glucocorticoid Mineralocorticoid Metabolism]] moved to [[Pathway:Rattus norvegicus:Glucocorticoid Mineralocorticoid Metabolism]]: Renaming species
7663view16:08, 18 December 2007MaintBotfixed category names
7362view12:42, 4 November 2007MaintBotAdded categories to GPML
19476view22:20, 22 May 2007M.Liebermangpml file for [[Rat:Glucocorticoid_Mineralocorticoid_Metabolism]]
19475view22:20, 22 May 2007Bconklingpml file for [[Rat:Glucocorticoid_Mineralocorticoid_Metabolism]]
6550view22:20, 22 May 2007Nsalomonisgpml file for [[Rat:Glucocorticoid_Mineralocorticoid_Metabolism]]

External references

DataNodes

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NameTypeDatabase referenceComment
(R)20-hydroxysteroid DhGeneProduct1.1.1.53, similiar SP:2BHD STREX
20b-Hydroxysteroid DhGeneProduct1.1.1.53, similiar SP:2BHD STREX
3-Oxo-5b-Steroid DhGeneProduct
3B-OH-delta-Steroid DhGeneProduct
Corticosterone 18-MonooxyGeneProductEC number: 1.14.15.5
Cortisone beta-reductaseGeneProduct1.3.1.3
Cyp11a1GeneProduct29680 (Entrez Gene)
Cyp11b1GeneProduct24293 (Entrez Gene)
Cyp17a1GeneProduct25146 (Entrez Gene)
Cyp21a1GeneProduct24298 (Entrez Gene) Homologus to SwissProtID: CPS1 MOUSE
Hsd11b1GeneProduct25116 (Entrez Gene)
Hsd11b2GeneProduct25117 (Entrez Gene)
RGD:708361GeneProduct191574 (Entrez Gene)
Steroid delta-IsomeraseGeneProduct

Annotated Interactions

No annotated interactions

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