Hybrid Pathway for Pancreatic Cancer (Homo sapiens)
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ArcPathVisio
Brace
Ellipse
EndoplasmicReticulum
GolgiApparatus
HexagonPathVisio
MimDegradation
Mitochondria
Octagon
PentagonPathVisio
Rectangle
RoundedRectangle
SarcoplasmicReticulum
TriangleEquilateralEast
TrianglePathVisio
none
Name: New Pathway
Description
No description
Comments
Pancreati
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
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Ontology Terms
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Pathway Ontology
:
niacin metabolic pathway
vitamin B3 metabolic pathway
Disease
:
Cell Type
:
plant cell
Bibliography
History
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Revision
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Time
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Comment
50003
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19:06, 3 August 2012
Pragat11
Deleted pathway:
49938
view
17:40, 1 August 2012
Pragat11
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ABL1
GeneProduct
ENSG00000097007 (Ensembl Human)
AC
Protein
ACHE
GeneProduct
ENSG00000087085 (Ensembl Human)
ADCY1
GeneProduct
107 (Entrez Gene)
ADORA1
GeneProduct
ENSG00000163485 (Ensembl Human)
ADORA2A/GPCR
GeneProduct
ENSG00000128271 (Ensembl Human)
AGPAT2/IP3
GeneProduct
ENSG00000169692 (Ensembl Human)
AKT1
GeneProduct
207 (Entrez Gene)
ANDR_HUMAN
Protein
P10275 (Uniprot/TrEMBL)
ANXA1
GeneProduct
ENSG00000135046 (Ensembl Human)
APAF1
GeneProduct
ENSG00000120868 (Ensembl Human)
APC
GeneProduct
ENSG00000134982 (Ensembl Human)
APP
GeneProduct
ENSG00000142192 (Ensembl Human)
ARF1
GeneProduct
ENSG00000143761 (Ensembl Human)
ASPP2_HUMAN
Protein
Q13625 (Uniprot/TrEMBL)
ATM/ATR
GeneProduct
ENSG00000149311 (Ensembl Human)
Aflibercept
Amsacrine
Amsacrine
Apoptosis
BAD
Protein
BAX/BAXA
GeneProduct
ENSG00000087088 (Ensembl Human)
BBC3/ PUMA
GeneProduct
ENSG00000105327 (Ensembl Human)
BCL2
GeneProduct
ENSG00000171791 (Ensembl Human)
BDNF
GeneProduct
ENSG00000176697 (Ensembl Human)
BID/BH3
GeneProduct
ENSG00000015475 (Ensembl Human)
BID
GeneProduct
ENSG00000015475 (Ensembl Human)
BLM
GeneProduct
ENSG00000197299 (Ensembl Human)
BRCA1
GeneProduct
ENSG00000012048 (Ensembl Human)
BRCA2
GeneProduct
ENSG00000139618 (Ensembl Human)
BRF1
GeneProduct
ENSG00000185024 (Ensembl Human)
BUB1B
GeneProduct
ENSG00000156970 (Ensembl Human)
Bleomycin
CAB39
GeneProduct
ENSG00000135932 (Ensembl Human)
CAMK2A/ CAMPK2
GeneProduct
ENSG00000070808 (Ensembl Human)
CAMP/ AMP
GeneProduct
ENSG00000164047 (Ensembl Human)
CAPN1
GeneProduct
ENSG00000014216 (Ensembl Human)
CASP10
GeneProduct
ENSG00000003400 (Ensembl Human)
CASP12
GeneProduct
ENSG00000204403 (Ensembl Human)
CASP3
GeneProduct
ENSG00000164305 (Ensembl Human)
CASP7
GeneProduct
ENSG00000165806 (Ensembl Human)
CASP8
GeneProduct
ENSG00000064012 (Ensembl Human)
CASP9
GeneProduct
ENSG00000132906 (Ensembl Human)
CBP_HUMAN
Protein
Q92793 (Uniprot/TrEMBL)
CCNA2
GeneProduct
ENSG00000145386 (Ensembl Human)
CCND1
GeneProduct
595 (Entrez Gene)
CCNE1
GeneProduct
ENSG00000105173 (Ensembl Human)
CD82
GeneProduct
ENSG00000085117 (Ensembl Human)
CDC25C/ MPIP3
GeneProduct
ENSG00000158402 (Ensembl Human)
CDK1
Protein
CDK2
GeneProduct
ENSG00000123374 (Ensembl Human)
CDK4/CDK6
GeneProduct
ENSG00000135446 (Ensembl Human)
CDK5R1 p35
Protein
CDKN1B
GeneProduct
ENSG00000111276 (Ensembl Human)
CDKN2A
Protein
CDKN2B
GeneProduct
ENSG00000147883 (Ensembl Human)
CDN1A_HUMAN/CIP1
Protein
P38936 (Uniprot/TrEMBL)
CHK1_HUMAN
Protein
O14757 (Uniprot/TrEMBL)
CHK2_HUMAN
Protein
O96017 (Uniprot/TrEMBL)
CR2
Protein
CREB1
GeneProduct
ENSG00000118260 (Ensembl Human)
CRHR1
GeneProduct
ENSG00000120088 (Ensembl Human)
CRK
GeneProduct
ENSG00000167193 (Ensembl Human)
CTNNB1
GeneProduct
ENSG00000168036 (Ensembl Human)
CUX1/ CASP/CDP
GeneProduct
ENSG00000160967 (Ensembl Human)
CYTC_HUMAN
Protein
P01034 (Uniprot/TrEMBL)
Camptothecin
Cobalt
Connexin
Protein
Corticosterone
DAG1
GeneProduct
ENSG00000173402 (Ensembl Human)
DAXX
GeneProduct
ENSG00000204209 (Ensembl Human)
DCC
GeneProduct
ENSG00000187323 (Ensembl Human)
DDIT3/ GADD153
GeneProduct
ENSG00000175197 (Ensembl Human)
DFFA
GeneProduct
ENSG00000160049 (Ensembl Human)
DFFB
GeneProduct
ENSG00000169598 (Ensembl Human)
DNA
DNA Damage Checkpoint
DNA Fragmentation
DNA Mutation
DNA Repair
DNA-PK
DPOLA_HUMAN
Protein
P09884 (Uniprot/TrEMBL)
Deferoxamine
Dexamethasone
Donepezil
E2AK2_HUMAN
Protein
P19525 (Uniprot/TrEMBL)
E2F1_HUMAN
Protein
Q01094 (Uniprot/TrEMBL)
E2F4
GeneProduct
ENSG00000205250 (Ensembl Human)
EGF
GeneProduct
1950 (Entrez Gene)
EGFR
GeneProduct
ENSG00000146648 (Ensembl Human)
EGR1
GeneProduct
ENSG00000120738 (Ensembl Human)
EP300
GeneProduct
2033 (Entrez Gene)
ERBB2
GeneProduct
ENSG00000141736 (Ensembl Human)
ERCC2/XPD
GeneProduct
ENSG00000104884 (Ensembl Human)
ERCC3/XPB
GeneProduct
ENSG00000163161 (Ensembl Human)
ERCC6
Protein
ESR1
GeneProduct
ENSG00000091831 (Ensembl Human)
ESR2
GeneProduct
ENSG00000140009 (Ensembl Human)
EZH2
GeneProduct
ENSG00000106462 (Ensembl Human)
Estradiol
Estrone
FADD
GeneProduct
ENSG00000168040 (Ensembl Human)
FANCG/ FANCs
GeneProduct
ENSG00000221829 (Ensembl Human)
FANCN/ PALB2
Protein
FAS
GeneProduct
ENSG00000026103 (Ensembl Human)
FASLG/FASL
GeneProduct
356 (Entrez Gene)
FGF2/ Growth Factors
GeneProduct
ENSG00000138685 (Ensembl Human)
FGF
GeneProduct
ENSG00000113578 (Ensembl Human)
FGFR1
GeneProduct
ENSG00000077782 (Ensembl Human)
FKBP1A
GeneProduct
ENSG00000088832 (Ensembl Human)
FKBP1B
GeneProduct
ENSG00000119782 (Ensembl Human)
FKBP3
GeneProduct
ENSG00000100442 (Ensembl Human)
FST
GeneProduct
ENSG00000134363 (Ensembl Human)
FTL
GeneProduct
ENSG00000087086 (Ensembl Human)
G-Proteins
GeneProduct
ENSG00000152256 (Ensembl Human)
G1 arrest
Protein
GA45A_HUMAN/ GADD45
Protein
P24522 (Uniprot/TrEMBL)
GF
Protein
GFR
Protein
GNAS/GS
GeneProduct
ENSG00000087460 (Ensembl Human)
GPCRs
Protein
GPRC5A
GeneProduct
ENSG00000013588 (Ensembl Human)
GR/NR3C1
Protein
GRB2
GeneProduct
ENSG00000177885 (Ensembl Human)
GSK3A/ GSK3
GeneProduct
ENSG00000105723 (Ensembl Human)
Gemcitabine
Gramicidin
HBx
Protein
HDAC8
GeneProduct
ENSG00000147099 (Ensembl Human)
HNF4A
GeneProduct
ENSG00000101076 (Ensembl Human)
HPGDS
GeneProduct
ENSG00000163106 (Ensembl Human)
HSP90AB1/ HSPS
GeneProduct
ENSG00000096384 (Ensembl Human)
Hydrocortisone
Hydroxyurea
IAPP
GeneProduct
ENSG00000121351 (Ensembl Human)
IASPP_HUMAN
Protein
Q8WUF5 (Uniprot/TrEMBL)
IBP3_HUMAN
Protein
P17936 (Uniprot/TrEMBL)
IGF
Protein
IKBA_HUMAN
Protein
P25963 (Uniprot/TrEMBL)
IKKA_HUMAN
Protein
O15111 (Uniprot/TrEMBL)
IL-3R
Protein
IL11
GeneProduct
ENSG00000095752 (Ensembl Human)
IL1R1
GeneProduct
ENSG00000115594 (Ensembl Human)
IL3
GeneProduct
ENSG00000164399 (Ensembl Human)
INHBA
GeneProduct
ENSG00000122641 (Ensembl Human)
Interferons
JUNB
GeneProduct
ENSG00000171223 (Ensembl Human)
JUND
GeneProduct
ENSG00000130522 (Ensembl Human)
JUN
GeneProduct
ENSG00000177606 (Ensembl Human)
KRAS
GeneProduct
ENSG00000133703 (Ensembl Human)
LEFTY1
GeneProduct
ENSG00000243709 (Ensembl Human)
LHB
Protein
LIG1
GeneProduct
ENSG00000105486 (Ensembl Human)
LIG3
GeneProduct
ENSG00000005156 (Ensembl Human)
LTBP1
GeneProduct
ENSG00000049323 (Ensembl Human)
Lanreotide
MAP2K1/ MEKs
GeneProduct
ENSG00000169032 (Ensembl Human)
MAP3K4
GeneProduct
ENSG00000085511 (Ensembl Human)
MAP3K5/ ASK1
GeneProduct
ENSG00000197442 (Ensembl Human)
MAPK1/MAPKs
GeneProduct
ENSG00000100030 (Ensembl Human)
MAPK14/ p38
GeneProduct
ENSG00000112062 (Ensembl Human)
MAPK3
GeneProduct
ENSG00000102882 (Ensembl Human)
MAPK4
GeneProduct
ENSG00000141639 (Ensembl Human)
MAPK7
GeneProduct
ENSG00000166484 (Ensembl Human)
MAPK8
GeneProduct
ENSG00000107643 (Ensembl Human)
MAPK9
GeneProduct
ENSG00000050748 (Ensembl Human)
MAT1_HUMAN/ CDK7
Protein
P51948 (Uniprot/TrEMBL)
MAX
GeneProduct
ENSG00000125952 (Ensembl Human)
MDA
Protein
MDM2
GeneProduct
ENSG00000135679 (Ensembl Human)
MDR1_HUMAN
Protein
P08183 (Uniprot/TrEMBL)
MEF2C
GeneProduct
ENSG00000081189 (Ensembl Human)
MLH1
GeneProduct
ENSG00000076242 (Ensembl Human)
MMP9
GeneProduct
ENSG00000137801 (Ensembl Human)
MPIP3_HUMAN
Protein
P30307 (Uniprot/TrEMBL)
MRE11_HUMAN
Protein
P49959 (Uniprot/TrEMBL)
MSH2
GeneProduct
ENSG00000095002 (Ensembl Human)
MSH3
GeneProduct
ENSG00000113318 (Ensembl Human)
MSH6
GeneProduct
ENSG00000116062 (Ensembl Human)
MST1
GeneProduct
ENSG00000173531 (Ensembl Human)
MTOR
Protein
MYC
GeneProduct
ENSG00000136997 (Ensembl Human)
MYT1
GeneProduct
4661 (Entrez Gene)
Methyl Methanesulfonate
Mitomycin
NCK1
GeneProduct
4690 (Entrez Gene)
NDKA_HUMAN
Protein
P15531 (Uniprot/TrEMBL)
NFKB1
GeneProduct
ENSG00000109320 (Ensembl Human)
NGF
GeneProduct
ENSG00000134259 (Ensembl Human)
NODAL
GeneProduct
ENSG00000156574 (Ensembl Human)
NOXA1
GeneProduct
ENSG00000188747 (Ensembl Human)
NT5C1A
GeneProduct
ENSG00000116981 (Ensembl Human)
NTF3
GeneProduct
ENSG00000185652 (Ensembl Human)
NTRK1
GeneProduct
ENSG00000198400 (Ensembl Human)
Niacinamide
Nocodazole
Nuclear Substrates
Protein
PAK1
GeneProduct
ENSG00000149269 (Ensembl Human)
PARP
GeneProduct
ENSG00000015475 (Ensembl Human)
PCAF
Protein
PCNA
GeneProduct
ENSG00000132646 (Ensembl Human)
PDE4B/PDE4B
GeneProduct
ENSG00000184588 (Ensembl Human)
PDGFA/PDGF
GeneProduct
5154 (Entrez Gene)
PDGFRA/ PDGFR
GeneProduct
5156 (Entrez Gene)
PDK1
GeneProduct
ENSG00000152256 (Ensembl Human)
PGH2_HUMAN/Cox1
Protein
P35354 (Uniprot/TrEMBL)
PIAS1
GeneProduct
ENSG00000033800 (Ensembl Human)
PIK3CA
GeneProduct
ENSG00000121879 (Ensembl Human)
PITX2
GeneProduct
ENSG00000164093 (Ensembl Human)
PLA2G4A/ cPLA2
GeneProduct
5321 (Entrez Gene)
PLCB_HUMAN
Protein
O15120 (Uniprot/TrEMBL)
PLK1
GeneProduct
ENSG00000166851 (Ensembl Human)
PLN
GeneProduct
ENSG00000198523 (Ensembl Human)
PML
GeneProduct
ENSG00000140464 (Ensembl Human)
PRKAA1/ PKA
GeneProduct
ENSG00000249325 (Ensembl Human)
PRKAA2/ Ampks
GeneProduct
ENSG00000162409 (Ensembl Human)
PRKCA/ PKCs
GeneProduct
ENSG00000154229 (Ensembl Human)
PRKCA
GeneProduct
ENSG00000154229 (Ensembl Human)
PTEN
GeneProduct
ENSG00000171862 (Ensembl Human)
PTGDS
GeneProduct
ENSG00000107317 (Ensembl Human)
PTGS2
GeneProduct
ENSG00000073756 (Ensembl Human)
PTK2/FAK
GeneProduct
ENSG00000169398 (Ensembl Human)
PTTG1
GeneProduct
ENSG00000164611 (Ensembl Human)
Paclitaxel
Q6LD43_HUMAN/ Ga
Protein
Q6LD43 (Uniprot/TrEMBL)
RAC1
GeneProduct
5879 (Entrez Gene)
RAD50
GeneProduct
ENSG00000113522 (Ensembl Human)
RAD51
GeneProduct
ENSG00000051180 (Ensembl Human)
RAD52
GeneProduct
5893 (Entrez Gene)
RAF1
GeneProduct
ENSG00000132155 (Ensembl Human)
RAP1A
GeneProduct
ENSG00000116473 (Ensembl Human)
RAP1A_HUMAN/Rap1
Protein
P62834 (Uniprot/TrEMBL)
RAPGEF3
GeneProduct
ENSG00000079337 (Ensembl Human)
RARA
GeneProduct
ENSG00000131759 (Ensembl Human)
RARB
GeneProduct
ENSG00000077092 (Ensembl Human)
RB1CC1
GeneProduct
ENSG00000023287 (Ensembl Human)
RBL1
GeneProduct
ENSG00000080839 (Ensembl Human)
RHEB
GeneProduct
ENSG00000106615 (Ensembl Human)
RNA pol
RPA1_HUMAN
Protein
O95602 (Uniprot/TrEMBL)
RRM1
GeneProduct
ENSG00000167325 (Ensembl Human)
RTK
Protein
RXRs
GeneProduct
ENSG00000186350 (Ensembl Human)
SAPL1_HUMAN/ SAPLa
Protein
Q6NUJ1 (Uniprot/TrEMBL)
SERPINB10
GeneProduct
ENSG00000242550 (Ensembl Human)
SHH
GeneProduct
ENSG00000164690 (Ensembl Human)
SIRT1
GeneProduct
ENSG00000096717 (Ensembl Human)
SMAD2/SMAD3
GeneProduct
ENSG00000175387 (Ensembl Human)
SMAD4
GeneProduct
ENSG00000141646 (Ensembl Human)
SMAD6/SMAD7
GeneProduct
ENSG00000137834 (Ensembl Human)
SMI
Protein
SMO
GeneProduct
ENSG00000128602 (Ensembl Human)
SOS1
GeneProduct
ENSG00000115904 (Ensembl Human)
SP1
GeneProduct
ENSG00000185591 (Ensembl Human)
SRC/NCOA1
GeneProduct
ENSG00000197122 (Ensembl Human)
SSTR2
GeneProduct
ENSG00000180616 (Ensembl Human)
SSTR3
GeneProduct
ENSG00000183473 (Ensembl Human)
SSTR5
GeneProduct
ENSG00000162009 (Ensembl Human)
STAT1
GeneProduct
ENSG00000115415 (Ensembl Human)
STAT5A/STATs
GeneProduct
ENSG00000126561 (Ensembl Human)
STK11/LKB1
GeneProduct
ENSG00000118046 (Ensembl Human)
STMN1
GeneProduct
ENSG00000117632 (Ensembl Human)
STRADA/ STRAD
GeneProduct
ENSG00000125695 (Ensembl Human)
Sirolimus
T2AG_HUMAN/TFFIIA
Protein
P52657 (Uniprot/TrEMBL)
TAU_HUMAN
Protein
P10636 (Uniprot/TrEMBL)
TBP
GeneProduct
ENSG00000112592 (Ensembl Human)
TFF1
GeneProduct
ENSG00000160182 (Ensembl Human)
TGFB1
GeneProduct
ENSG00000105329 (Ensembl Human)
TGFBR1
GeneProduct
ENSG00000106799 (Ensembl Human)
TGFBR2
GeneProduct
ENSG00000163513 (Ensembl Human)
THBS1
GeneProduct
ENSG00000137801 (Ensembl Human)
TNF
GeneProduct
ENSG00000232810 (Ensembl Human)
TNFRSF1A
GeneProduct
ENSG00000067182 (Ensembl Human)
TOP1
GeneProduct
ENSG00000198900 (Ensembl Human)
TOP2A/TOP2
GeneProduct
ENSG00000131747 (Ensembl Human)
TP53
GeneProduct
ENSG00000141510 (Ensembl Human)
TRAF2
GeneProduct
ENSG00000127191 (Ensembl Human)
TUBA1A
GeneProduct
ENSG00000167552 (Ensembl Human)
TUBB1
GeneProduct
ENSG00000101162 (Ensembl Human)
TYMS/TS
GeneProduct
ENSG00000176890 (Ensembl Human)
Tamoxifen
Teniposide
Theobromine
Topotecan
Translation
Tretinoin
Triamcinolone Acetonide
Trichostatin A
Tumor Progression
UCN
GeneProduct
ENSG00000163794 (Ensembl Human)
VEGF/ VEGF-A
GeneProduct
ENSG00000112715 (Ensembl Human)
WRN
GeneProduct
ENSG00000165392 (Ensembl Human)
WT1
GeneProduct
ENSG00000184937 (Ensembl Human)
XAB2
Protein
p85
Protein
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Bibliography
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DataNodes
Annotated Interactions
No annotated interactions