Private (Homo sapiens)

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FTLSRC/NCOA1Tretinoin DNARAF1KRASMAPK1/MAPKsAKT1IKBAIKKANFKB1STAT5A/STATsNuclear SubstratesCDK4/CDK6MDM2CDKN2AARF1CDK2CCND1TP53CCNE1CDN1AApoptosisp85PTENSERPINB10PIK3CARBL1BAX/BAXABID/BH3SMICASP3CASP8BCL2CYTCAPAF1CASP9SMAD6/SMAD7SMAD4SMAD2/SMAD3APCE2F4IAPPPCAFSP1CDKN2BMYCG1 arrestBRCA1ATMBRCA2MAT1DNA RepairNDKARAD50PTTG1BUB1BGSK3A/ GSK3CTNNB1CREB1CBPHNF4ACDK1CCNA2MAP3K5/ ASK1DAXXTGFB1FASLG/FASLFASTGFBR1CR2TBPSIRT1ERCC6RNA polXAB2ERCC2/XPDMAPK9MAPK3MAP2K1/ MEKsPRKCA/ PKCsPRKCACDKN1BEGFRCDC25C/ MPIP3CHK1MAPK8GA45AIGFMRE11_HUMANABL1RAD52RAD51MYT1PLK1CHK2FASCASP10FADDDFFADFFBCASP7DNA FragmentationNTRK1IL-3RIL3NGFCASP12CAPN1NT5C1AHBxLHBBDNFNTF3EGFFGFR1PDGFRA/ PDGFRPDGFA/PDGFSAPL1IL1R1TRAF2SOS1GRB2PLA2G4A/ cPLA2STMN1TAUIL11TNFRSF1ATNFMAPK4MAPK14/ p38MST1CUX1/ CASP/CDPMEF2CMAXDDIT3/ GADD153JUNDJUNMAPK7ANDR_HUMANBADGFRGFE2F1_HUMANRB1CC1RAC1STAT1PCNADNA-PKDNA Damage CheckpointTHBS1LTBP1FSTINHBALEFTY1NODALPITX2BIDQ6LD43MPIP3DAG1AGPAT2/IP3PLCBCAMK2A/ CAMPK2NOXA1BBC3/ PUMAPTK2/FAKPAK1NCK1CRKGR/NR3C1ACT2AGTFF1DNA MutationMDAPGH2PRKAA1/ PKARAPGEF3RAP1ABRF1TranslationFANCG/ FANCsPDK1STK11/LKB1CAMP/ AMPCAB39STRADA/ STRADPRKAA2/ AmpksCDK5R1EGR1ERCC3/XPBFANCN/ PALB2DCCMLH1MSH2MSH3MSH6TGFBR2SMOSHHPDK1G-ProteinsRAP1APARPTUBA1ATUBB1ConnexinRTKMTORFGFFGF2ESR1ADCY1ADORA2A/GPCRGNAS/GSPLNFKBP1AMMP9VEGF/ VEGF-APDE4B/PDE4BSSTR2SSTR5SSTR3RRM1RRM1TYMS/TSFKBP1BMAP3K4HSP90AB1/ HSPSEZH2CD82JUNBRHEBFKBP3GPCRsGPRC5AADORA1RARARXRsRARBTumor ProgressionTOP1ESR2Tamoxifen Dexamethasone ANXA1LIG1LIG3Teniposide Estradiol Triamcinolone AcetonideHydrocortisone Hydroxyurea TOP2A/TOP2Topotecan APPACHEDonepezil Amsacrine Gemcitabine Mitomycin EstroneSirolimus Theobromine Paclitaxel CamptothecinNiacinamideLanreotide Donepezil HDAC8Trichostatin A AfliberceptHPGDSPTGDSNocodazoleAmsacrineBleomycinCorticosteroneDeferoxamineMethyl MethanesulfonateTriamcinolone AcetonidePTGS2WRNRPA1_HUMANCobaltIASPPEP300MDR1BLMGramicidinE2AK2InterferonsPIAS1PMLDPOLAASPP2_HUMANERBB2IBP3CRHR1UCNWT1XRCC1TFIIHXPAATRIPRAD1RAD9Hus1CADCTIPRBBP8ATREXO1INSRNotch1MCM2MCM6MCM4MCM7MDC1NBS1p70-s6kp90-rskAPEXTDGTopbp1MKK6MKK3elk1ATF2ORC5LORC1L


Description

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Pancreati

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History

CompareRevisionActionTimeUserComment
53134view01:54, 30 October 2012MaintBotDeleted pathway: unclear what it was
50200view14:37, 9 August 2012Pragat11New pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABL1GeneProductENSG00000097007 (Ensembl Human)
ACProtein
ACHEGeneProductENSG00000087085 (Ensembl Human)
ADCY1GeneProduct107 (Entrez Gene)
ADORA1GeneProductENSG00000163485 (Ensembl Human)
ADORA2A/GPCRGeneProductENSG00000128271 (Ensembl Human)
AGPAT2/IP3GeneProductENSG00000169692 (Ensembl Human)
AKT1GeneProduct207 (Entrez Gene)
ANDR_HUMANProteinP10275 (Uniprot/TrEMBL)
ANXA1GeneProductENSG00000135046 (Ensembl Human)
APAF1GeneProductENSG00000120868 (Ensembl Human)
APCGeneProductENSG00000134982 (Ensembl Human)
APEXGeneProductENSG00000067182 (Ensembl Human)
APPGeneProductENSG00000142192 (Ensembl Human)
ARF1GeneProductENSG00000143761 (Ensembl Human)
ASPP2_HUMANProteinQ13625 (Uniprot/TrEMBL)
ATF2Protein
ATMGeneProductENSG00000149311 (Ensembl Human)
ATRGeneProductENSG00000149311 (Ensembl Human)
ATRIPGeneProductENSG00000051180 (Ensembl Human)
Aflibercept
Amsacrine
Amsacrine
Apoptosis
BADProtein
BAX/BAXAGeneProductENSG00000087088 (Ensembl Human)
BBC3/ PUMAGeneProductENSG00000105327 (Ensembl Human)
BCL2GeneProductENSG00000171791 (Ensembl Human)
BDNFGeneProductENSG00000176697 (Ensembl Human)
BID/BH3GeneProductENSG00000015475 (Ensembl Human)
BIDGeneProductENSG00000015475 (Ensembl Human)
BLMGeneProductENSG00000197299 (Ensembl Human)
BRCA1GeneProductENSG00000012048 (Ensembl Human)
BRCA2GeneProductENSG00000139618 (Ensembl Human)
BRF1GeneProductENSG00000185024 (Ensembl Human)
BUB1BGeneProductENSG00000156970 (Ensembl Human)
Bleomycin
CAB39GeneProductENSG00000135932 (Ensembl Human)
CADGeneProductENSG00000051180 (Ensembl Human)
CAMK2A/ CAMPK2GeneProductENSG00000070808 (Ensembl Human)
CAMP/ AMPGeneProductENSG00000164047 (Ensembl Human)
CAPN1GeneProductENSG00000014216 (Ensembl Human)
CASP10GeneProductENSG00000003400 (Ensembl Human)
CASP12GeneProductENSG00000204403 (Ensembl Human)
CASP3GeneProductENSG00000164305 (Ensembl Human)
CASP7GeneProductENSG00000165806 (Ensembl Human)
CASP8GeneProductENSG00000064012 (Ensembl Human)
CASP9GeneProductENSG00000132906 (Ensembl Human)
CBPProteinQ92793 (Uniprot/TrEMBL)
CCNA2GeneProductENSG00000145386 (Ensembl Human)
CCND1GeneProduct595 (Entrez Gene)
CCNE1GeneProductENSG00000105173 (Ensembl Human)
CD82GeneProductENSG00000085117 (Ensembl Human)
CDC25C/ MPIP3GeneProductENSG00000158402 (Ensembl Human)
CDK1Protein
CDK2GeneProductENSG00000123374 (Ensembl Human)
CDK4/CDK6GeneProductENSG00000135446 (Ensembl Human)
CDK5R1 Protein
CDKN1BGeneProductENSG00000111276 (Ensembl Human)
CDKN2AProtein
CDKN2BGeneProductENSG00000147883 (Ensembl Human)
CDN1AProteinP38936 (Uniprot/TrEMBL)
CHK1ProteinO14757 (Uniprot/TrEMBL)
CHK2ProteinO96017 (Uniprot/TrEMBL)
CR2Protein
CREB1GeneProductENSG00000118260 (Ensembl Human)
CRHR1GeneProductENSG00000120088 (Ensembl Human)
CRKGeneProductENSG00000167193 (Ensembl Human)
CTIPGeneProductENSG00000051180 (Ensembl Human)
CTNNB1GeneProductENSG00000168036 (Ensembl Human)
CUX1/ CASP/CDPGeneProductENSG00000160967 (Ensembl Human)
CYTCProteinP01034 (Uniprot/TrEMBL)
Camptothecin
Cobalt
ConnexinProtein
Corticosterone
DAG1GeneProductENSG00000173402 (Ensembl Human)
DAXXGeneProductENSG00000204209 (Ensembl Human)
DCCGeneProductENSG00000187323 (Ensembl Human)
DDIT3/ GADD153GeneProductENSG00000175197 (Ensembl Human)
DFFAGeneProductENSG00000160049 (Ensembl Human)
DFFBGeneProductENSG00000169598 (Ensembl Human)
DNA
DNA Damage Checkpoint
DNA Fragmentation
DNA Mutation
DNA Repair
DNA-PK
DPOLAProteinP09884 (Uniprot/TrEMBL)
Deferoxamine
Dexamethasone
Donepezil
E2AK2ProteinP19525 (Uniprot/TrEMBL)
E2F1_HUMANProteinQ01094 (Uniprot/TrEMBL)
E2F4GeneProductENSG00000205250 (Ensembl Human)
EGFGeneProduct1950 (Entrez Gene)
EGFRGeneProductENSG00000146648 (Ensembl Human)
EGR1GeneProductENSG00000120738 (Ensembl Human)
EP300GeneProduct2033 (Entrez Gene)
ERBB2GeneProductENSG00000141736 (Ensembl Human)
ERCC2/XPDGeneProductENSG00000104884 (Ensembl Human)
ERCC3/XPBGeneProductENSG00000163161 (Ensembl Human)
ERCC6Protein
ESR1GeneProductENSG00000091831 (Ensembl Human)
ESR2GeneProductENSG00000140009 (Ensembl Human)
EXO1GeneProductENSG00000051180 (Ensembl Human)
EZH2GeneProductENSG00000106462 (Ensembl Human)
Estradiol
Estrone
FADDGeneProductENSG00000168040 (Ensembl Human)
FANCG/ FANCsGeneProductENSG00000221829 (Ensembl Human)
FANCN/ PALB2Protein
FASGeneProductENSG00000026103 (Ensembl Human)
FASLG/FASLGeneProduct356 (Entrez Gene)
FGF2GeneProductENSG00000138685 (Ensembl Human)
FGFGeneProductENSG00000113578 (Ensembl Human)
FGFR1GeneProductENSG00000077782 (Ensembl Human)
FKBP1AGeneProductENSG00000088832 (Ensembl Human)
FKBP1BGeneProductENSG00000119782 (Ensembl Human)
FKBP3GeneProductENSG00000100442 (Ensembl Human)
FSTGeneProductENSG00000134363 (Ensembl Human)
FTLGeneProductENSG00000087086 (Ensembl Human)
G-ProteinsGeneProductENSG00000152256 (Ensembl Human)
G1 arrestProtein
GA45A ProteinP24522 (Uniprot/TrEMBL)
GFProtein
GFRProtein
GNAS/GSGeneProductENSG00000087460 (Ensembl Human)
GPCRsProtein
GPRC5AGeneProductENSG00000013588 (Ensembl Human)
GR/NR3C1Protein
GRB2GeneProductENSG00000177885 (Ensembl Human)
GSK3A/ GSK3GeneProductENSG00000105723 (Ensembl Human)
Gemcitabine
Gramicidin
HBxProtein
HDAC8GeneProductENSG00000147099 (Ensembl Human)
HNF4AGeneProductENSG00000101076 (Ensembl Human)
HPGDSGeneProductENSG00000163106 (Ensembl Human)
HSP90AB1/ HSPSGeneProductENSG00000096384 (Ensembl Human)
Hus1GeneProductENSG00000067182 (Ensembl Human)
Hydrocortisone
Hydroxyurea
IAPPGeneProductENSG00000121351 (Ensembl Human)
IASPPProteinQ8WUF5 (Uniprot/TrEMBL)
IBP3ProteinP17936 (Uniprot/TrEMBL)
IGFProtein
IKBAProteinP25963 (Uniprot/TrEMBL)
IKKAProteinO15111 (Uniprot/TrEMBL)
IL-3RProtein
IL11GeneProductENSG00000095752 (Ensembl Human)
IL1R1GeneProductENSG00000115594 (Ensembl Human)
IL3GeneProductENSG00000164399 (Ensembl Human)
INHBAGeneProductENSG00000122641 (Ensembl Human)
INSRGeneProductENSG00000051180 (Ensembl Human)
Interferons
JUNBGeneProductENSG00000171223 (Ensembl Human)
JUNDGeneProductENSG00000130522 (Ensembl Human)
JUNGeneProductENSG00000177606 (Ensembl Human)
KRASGeneProductENSG00000133703 (Ensembl Human)
LEFTY1GeneProductENSG00000243709 (Ensembl Human)
LHBProtein
LIG1GeneProductENSG00000105486 (Ensembl Human)
LIG3GeneProductENSG00000005156 (Ensembl Human)
LTBP1GeneProductENSG00000049323 (Ensembl Human)
Lanreotide
MAP2K1/ MEKsGeneProductENSG00000169032 (Ensembl Human)
MAP3K4GeneProductENSG00000085511 (Ensembl Human)
MAP3K5/ ASK1GeneProductENSG00000197442 (Ensembl Human)
MAPK1/MAPKsGeneProductENSG00000100030 (Ensembl Human)
MAPK14/ p38GeneProductENSG00000112062 (Ensembl Human)
MAPK3GeneProductENSG00000102882 (Ensembl Human)
MAPK4GeneProductENSG00000141639 (Ensembl Human)
MAPK7GeneProductENSG00000166484 (Ensembl Human)
MAPK8GeneProductENSG00000107643 (Ensembl Human)
MAPK9GeneProductENSG00000050748 (Ensembl Human)
MAT1ProteinP51948 (Uniprot/TrEMBL)
MAXGeneProductENSG00000125952 (Ensembl Human)
MCM2GeneProductENSG00000051180 (Ensembl Human)
MCM4GeneProductENSG00000051180 (Ensembl Human)
MCM6GeneProductENSG00000051180 (Ensembl Human)
MCM7GeneProductENSG00000051180 (Ensembl Human)
MDAProtein
MDC1GeneProductENSG00000051180 (Ensembl Human)
MDM2GeneProductENSG00000135679 (Ensembl Human)
MDR1ProteinP08183 (Uniprot/TrEMBL)
MEF2CGeneProductENSG00000081189 (Ensembl Human)
MKK3Protein
MKK6Protein
MLH1GeneProductENSG00000076242 (Ensembl Human)
MMP9GeneProductENSG00000137801 (Ensembl Human)
MPIP3ProteinP30307 (Uniprot/TrEMBL)
MRE11_HUMANProteinP49959 (Uniprot/TrEMBL)
MSH2GeneProductENSG00000095002 (Ensembl Human)
MSH3GeneProductENSG00000113318 (Ensembl Human)
MSH6GeneProductENSG00000116062 (Ensembl Human)
MST1GeneProductENSG00000173531 (Ensembl Human)
MTORProtein
MYCGeneProductENSG00000136997 (Ensembl Human)
MYT1GeneProduct4661 (Entrez Gene)
Methyl Methanesulfonate
Mitomycin
NBS1GeneProductENSG00000113522 (Ensembl Human)
NCK1GeneProduct4690 (Entrez Gene)
NDKAProteinP15531 (Uniprot/TrEMBL)
NFKB1GeneProductENSG00000109320 (Ensembl Human)
NGFGeneProductENSG00000134259 (Ensembl Human)
NODALGeneProductENSG00000156574 (Ensembl Human)
NOXA1GeneProductENSG00000188747 (Ensembl Human)
NT5C1AGeneProductENSG00000116981 (Ensembl Human)
NTF3GeneProductENSG00000185652 (Ensembl Human)
NTRK1GeneProductENSG00000198400 (Ensembl Human)
Niacinamide
Nocodazole
Notch1 GeneProductENSG00000051180 (Ensembl Human)
Nuclear SubstratesProtein
ORC1LGeneProductENSG00000051180 (Ensembl Human)
ORC5LGeneProductENSG00000051180 (Ensembl Human)
PAK1GeneProductENSG00000149269 (Ensembl Human)
PARPGeneProductENSG00000015475 (Ensembl Human)
PCAFProtein
PCNAGeneProductENSG00000132646 (Ensembl Human)
PDE4B/PDE4B GeneProductENSG00000184588 (Ensembl Human)
PDGFA/PDGFGeneProduct5154 (Entrez Gene)
PDGFRA/ PDGFRGeneProduct5156 (Entrez Gene)
PDK1GeneProductENSG00000152256 (Ensembl Human)
PGH2ProteinP35354 (Uniprot/TrEMBL)
PIAS1GeneProductENSG00000033800 (Ensembl Human)
PIK3CAGeneProductENSG00000121879 (Ensembl Human)
PITX2GeneProductENSG00000164093 (Ensembl Human)
PLA2G4A/ cPLA2GeneProduct5321 (Entrez Gene)
PLCBProteinO15120 (Uniprot/TrEMBL)
PLK1GeneProductENSG00000166851 (Ensembl Human)
PLNGeneProductENSG00000198523 (Ensembl Human)
PMLGeneProductENSG00000140464 (Ensembl Human)
PRKAA1/ PKA GeneProductENSG00000249325 (Ensembl Human)
PRKAA2/ AmpksGeneProductENSG00000162409 (Ensembl Human)
PRKCA/ PKCsGeneProductENSG00000154229 (Ensembl Human)
PRKCAGeneProductENSG00000154229 (Ensembl Human)
PTENGeneProductENSG00000171862 (Ensembl Human)
PTGDSGeneProductENSG00000107317 (Ensembl Human)
PTGS2GeneProductENSG00000073756 (Ensembl Human)
PTK2/FAKGeneProductENSG00000169398 (Ensembl Human)
PTTG1GeneProductENSG00000164611 (Ensembl Human)
Paclitaxel
Q6LD43ProteinQ6LD43 (Uniprot/TrEMBL)
RAC1GeneProduct5879 (Entrez Gene)
RAD1GeneProductENSG00000067182 (Ensembl Human)
RAD50GeneProductENSG00000113522 (Ensembl Human)
RAD51GeneProductENSG00000051180 (Ensembl Human)
RAD52GeneProduct5893 (Entrez Gene)
RAD9GeneProductENSG00000067182 (Ensembl Human)
RAF1GeneProductENSG00000132155 (Ensembl Human)
RAP1A ProteinP62834 (Uniprot/TrEMBL)
RAP1AGeneProductENSG00000116473 (Ensembl Human)
RAPGEF3GeneProductENSG00000079337 (Ensembl Human)
RARAGeneProductENSG00000131759 (Ensembl Human)
RARBGeneProductENSG00000077092 (Ensembl Human)
RB1CC1GeneProductENSG00000023287 (Ensembl Human)
RBBP8GeneProductENSG00000051180 (Ensembl Human)
RBL1GeneProductENSG00000080839 (Ensembl Human)
RHEBGeneProductENSG00000106615 (Ensembl Human)
RNA pol
RPA1_HUMANProteinO95602 (Uniprot/TrEMBL)
RRM1GeneProductENSG00000167325 (Ensembl Human)
RTKProtein
RXRsGeneProductENSG00000186350 (Ensembl Human)
SAPL1ProteinQ6NUJ1 (Uniprot/TrEMBL)
SERPINB10GeneProductENSG00000242550 (Ensembl Human)
SHHGeneProductENSG00000164690 (Ensembl Human)
SIRT1GeneProductENSG00000096717 (Ensembl Human)
SMAD2/SMAD3GeneProductENSG00000175387 (Ensembl Human)
SMAD4GeneProductENSG00000141646 (Ensembl Human)
SMAD6/SMAD7GeneProductENSG00000137834 (Ensembl Human)
SMIProtein
SMOGeneProductENSG00000128602 (Ensembl Human)
SOS1GeneProductENSG00000115904 (Ensembl Human)
SP1GeneProductENSG00000185591 (Ensembl Human)
SRC/NCOA1GeneProductENSG00000197122 (Ensembl Human)
SSTR2GeneProductENSG00000180616 (Ensembl Human)
SSTR3GeneProductENSG00000183473 (Ensembl Human)
SSTR5GeneProductENSG00000162009 (Ensembl Human)
STAT1GeneProductENSG00000115415 (Ensembl Human)
STAT5A/STATsGeneProductENSG00000126561 (Ensembl Human)
STK11/LKB1GeneProductENSG00000118046 (Ensembl Human)
STMN1GeneProductENSG00000117632 (Ensembl Human)
STRADA/ STRADGeneProductENSG00000125695 (Ensembl Human)
Sirolimus
T2AGProteinP52657 (Uniprot/TrEMBL)
TAUProteinP10636 (Uniprot/TrEMBL)
TBPGeneProductENSG00000112592 (Ensembl Human)
TDGGeneProductENSG00000067182 (Ensembl Human)
TFF1GeneProductENSG00000160182 (Ensembl Human)
TFIIHGeneProductENSG00000051180 (Ensembl Human)
TGFB1GeneProductENSG00000105329 (Ensembl Human)
TGFBR1GeneProductENSG00000106799 (Ensembl Human)
TGFBR2GeneProductENSG00000163513 (Ensembl Human)
THBS1GeneProductENSG00000137801 (Ensembl Human)
TNFGeneProductENSG00000232810 (Ensembl Human)
TNFRSF1AGeneProductENSG00000067182 (Ensembl Human)
TOP1GeneProductENSG00000198900 (Ensembl Human)
TOP2A/TOP2GeneProductENSG00000131747 (Ensembl Human)
TP53GeneProductENSG00000141510 (Ensembl Human)
TRAF2GeneProductENSG00000127191 (Ensembl Human)
TUBA1AGeneProductENSG00000167552 (Ensembl Human)
TUBB1GeneProductENSG00000101162 (Ensembl Human)
TYMS/TSGeneProductENSG00000176890 (Ensembl Human)
Tamoxifen
Teniposide
Theobromine
Topbp1GeneProductENSG00000051180 (Ensembl Human)
Topotecan
Translation
Tretinoin
Triamcinolone Acetonide
Trichostatin A
Tumor Progression
UCNGeneProductENSG00000163794 (Ensembl Human)
VEGF/ VEGF-AGeneProductENSG00000112715 (Ensembl Human)
WRNGeneProductENSG00000165392 (Ensembl Human)
WT1GeneProductENSG00000184937 (Ensembl Human)
XAB2Protein
XPAGeneProductENSG00000051180 (Ensembl Human)
XRCC1GeneProductENSG00000067182 (Ensembl Human)
elk1Protein
p70-s6kGeneProductENSG00000051180 (Ensembl Human)
p85Protein
p90-rskGeneProductENSG00000051180 (Ensembl Human)

Annotated Interactions

No annotated interactions
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