Interleukin-11 Signaling Pathway (Homo sapiens)

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IKBKBPPIK3R2PIL6STIL11RAPhosphatidicTh2 polarization of Migration of chondrosarcoma cellsInhibitionInterleukin-11 Signaling PathwayGastric inflammation and associated tumorigenesisEndometrial epithelial cell adhesionOsteoblastic differentiation of periodontal ligament cellsIL11RAIL6STYES1PPJAK2PSTAT3PIL11IL11PIK3R1PPPP2R4RAF1PHRASPTPN11PGRB2FYNPRPS6PRPS6KA1PAKT1PMAPK3MAPK1PPSTAT1PCREB1ATF1PPCHUKPRELAPBIRC5BCL2SOCS3RUNX2BGLAPIBSPICAM1Phospholipase DSOCS3SRCPJAK1PSTAT3PTYK2PMAP2K1MAP2K2RPS6KB1PRELAFESPacidCD4+ T cellsTGFB1Regulation of macrophage effector functionPIAS1PIAS3PIAS1PIAS3ITGA2 Antiapoptotic effects to support mucosal integrityCYNUCYNUCYNUSTAT1PCYNUPDPK1PProteinTransportPositive regulation of gene expressionLeads to through unknown mechanismTranslocation Induced catalysisProtein-protein interactionLEGENDNucleusCytoplasmCYNUmRNAReceptorLigandProteinEnzyme complexLeads to positive regulation of gene expressionSmall molecule


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CompareRevisionActionTimeUserComment
51872view11:25, 24 September 2012NetPathDeleted pathway: legend not visible
51862view07:33, 24 September 2012NetPathNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AKT1GeneProduct207 (Entrez Gene)
ATF1GeneProduct466 (Entrez Gene)
BCL2GeneProduct596 (Entrez Gene)
BGLAPGeneProduct632 (Entrez Gene)
BIRC5GeneProduct332 (Entrez Gene)
CHUKGeneProduct1147 (Entrez Gene)
CREB1GeneProduct1385 (Entrez Gene)
FESGeneProduct
FYNGeneProduct2534 (Entrez Gene)
GRB2GeneProduct2885 (Entrez Gene)
HRASGeneProduct3265 (Entrez Gene)
IBSPGeneProduct3381 (Entrez Gene)
ICAM1GeneProduct3383 (Entrez Gene)
IKBKBGeneProduct3551 (Entrez Gene)
IL11GeneProduct3589 (Entrez Gene)
IL11RAGeneProduct3590 (Entrez Gene)
IL6STGeneProduct3572 (Entrez Gene)
ITGA2GeneProduct3673 (Entrez Gene)
JAK1GeneProduct3716 (Entrez Gene)
JAK2GeneProduct3717 (Entrez Gene)
MAP2K1GeneProduct
MAP2K2GeneProduct
MAPK1GeneProduct5594 (Entrez Gene)
MAPK3GeneProduct5595 (Entrez Gene)
PDPK1GeneProduct5170 (Entrez Gene)
PIAS1GeneProduct8554 (Entrez Gene)
PIAS3GeneProduct10401 (Entrez Gene)
PIK3R1GeneProduct5295 (Entrez Gene)
PIK3R2GeneProduct5296 (Entrez Gene)
PPP2R4GeneProduct5524 (Entrez Gene)
PTPN11GeneProduct5781 (Entrez Gene)
RAF1GeneProduct5894 (Entrez Gene)
RELAGeneProduct5970 (Entrez Gene)
RPS6GeneProduct6194 (Entrez Gene)
RPS6KA1GeneProduct6195 (Entrez Gene)
RPS6KB1GeneProduct
RUNX2GeneProduct860 (Entrez Gene)
SOCS3GeneProduct9021 (Entrez Gene)
SRCGeneProduct6714 (Entrez Gene)
STAT1GeneProduct6772 (Entrez Gene)
STAT3GeneProduct6774 (Entrez Gene)
TGFB1GeneProduct7040 (Entrez Gene)
TYK2GeneProduct7297 (Entrez Gene)
YES1GeneProduct7525 (Entrez Gene)

Annotated Interactions

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