IL11 signaling (Homo sapiens)

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IKBKBPPIK3R2PIL6STIL11RAInhibitionGastric inflammation and associated tumorigenesisPhosphatidicInterleukin-11 Signaling PathwayTh2 polarization ofEndometrial epithelial cell adhesionOsteoblastic differentiation of periodontal ligament cells Migration of chondrosarcoma cellsIL11RAIL6STYES1PPJAK2STAT3PPIL11IL11PIK3R1PPPP2R4RAF1PHRASPTPN11PGRB2FYNPRPS6RPS6KA1PPAKT1PMAPK3PMAPK1PSTAT1PCREB1PATF1PCHUKPRELAPBIRC5BCL2SOCS3RUNX2BGLAPIBSPICAM1Phospholipase DSOCS3SRCPJAK1PSTAT3PTYK2PMAP2K1MAP2K2RPS6KB1PRELAFESPacidCD4+ T cellsTGFB1Regulation of macrophage effector functionPIAS1PIAS3PIAS1PIAS3ITGA2 Antiapoptotic effects to support mucosal integrityCYNUCYNUCYNUSTAT1PCYNUPDPK1PProteinTransportPositive regulation of gene expressionLeads to through unknown mechanismTranslocation Induced catalysisProtein-protein interactionLEGENDNucleusCytoplasmCYNUmRNAReceptorLigandProteinLeads to positive regulation of gene expressionSmall moleculeProteinInduced activation


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Bibliography

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History

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CompareRevisionActionTimeUserComment
142057view22:50, 30 November 2025EweitzRefine state positions
142056view22:49, 30 November 2025EweitzEconomize layout
142055view22:48, 30 November 2025EweitzRemove deprecated metadata fields
136878view17:13, 25 February 2025EgonwModified description
129669view00:41, 22 May 2024EweitzModified title
126373view17:52, 25 April 2023EgonwLicense is CCZero (more specific)
120725view01:34, 24 December 2021EweitzStandardize font, weight, case
119743view13:19, 11 August 2021L DupuisConverted interactions to graphical lines in legend
117205view09:23, 19 May 2021EweitzModified title
106623view20:50, 12 September 2019KhanspersModified description
105630view05:03, 10 August 2019KhanspersModified description
79525view09:53, 24 March 2015Zariaddes ID for MAP2K!,MAP2K2,RPS6KB1 and FES
71360view18:36, 17 October 2013MaintBotAutomated update of data sources
67406view10:57, 26 June 2013DdiglesOntology Term : 'interleukin-11 signaling pathway' added !
63224view21:03, 8 May 2013MaintBotUpdating gpml version
53108view01:15, 30 October 2012MaintBotModified categories
52830view05:36, 23 October 2012NetPathModified description
52829view05:34, 23 October 2012NetPathNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AKT1GeneProduct207 (Entrez Gene)
ATF1GeneProduct466 (Entrez Gene)
BCL2GeneProduct596 (Entrez Gene)
BGLAPGeneProduct632 (Entrez Gene)
BIRC5GeneProduct332 (Entrez Gene)
CHUKGeneProduct1147 (Entrez Gene)
CREB1GeneProduct1385 (Entrez Gene)
FESGeneProduct
FYNGeneProduct2534 (Entrez Gene)
GRB2GeneProduct2885 (Entrez Gene)
HRASGeneProduct3265 (Entrez Gene)
IBSPGeneProduct3381 (Entrez Gene)
ICAM1GeneProduct3383 (Entrez Gene)
IKBKBGeneProduct3551 (Entrez Gene)
IL11GeneProduct3589 (Entrez Gene)
IL11RAGeneProduct3590 (Entrez Gene)
IL6STGeneProduct3572 (Entrez Gene)
ITGA2GeneProduct3673 (Entrez Gene)
JAK1GeneProduct3716 (Entrez Gene)
JAK2GeneProduct3717 (Entrez Gene)
MAP2K1GeneProduct
MAP2K2GeneProduct
MAPK1GeneProduct5594 (Entrez Gene)
MAPK3GeneProduct5595 (Entrez Gene)
PDPK1GeneProduct5170 (Entrez Gene)
PIAS1GeneProduct8554 (Entrez Gene)
PIAS3GeneProduct10401 (Entrez Gene)
PIK3R1GeneProduct5295 (Entrez Gene)
PIK3R2GeneProduct5296 (Entrez Gene)
PPP2R4GeneProduct5524 (Entrez Gene)
PTPN11GeneProduct5781 (Entrez Gene)
RAF1GeneProduct5894 (Entrez Gene)
RELAGeneProduct5970 (Entrez Gene)
RPS6GeneProduct6194 (Entrez Gene)
RPS6KA1GeneProduct6195 (Entrez Gene)
RPS6KB1GeneProduct
RUNX2GeneProduct860 (Entrez Gene)
SOCS3GeneProduct9021 (Entrez Gene)
SRCGeneProduct6714 (Entrez Gene)
STAT1GeneProduct6772 (Entrez Gene)
STAT3GeneProduct6774 (Entrez Gene)
TGFB1GeneProduct7040 (Entrez Gene)
TYK2GeneProduct7297 (Entrez Gene)
YES1GeneProduct7525 (Entrez Gene)

Annotated Interactions

No annotated interactions

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