Nuclear factor, erythroid-derived 2, like 2 signaling pathway (Rattus norvegicus)

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***MKK3/6MEK1/2NUCLEUSp21p62CITOPLASMPKCPI3KEXTRACELLULAR SPACEERK1/2JNK1/2Nfe2l2PrkcbDnajb9PROTEOSOMEDEGRADATIONOF NFE2L2Gstm5VcpGstt1Pik3cbMapk1Ub2Slc2a1Ephx1Mapk8CebpaFosl1UbbPik3r2Prkd1MrasKeap1Map2k3Akr1a1Pik3cdFth1Eif2ak3Usp14MafkBard1FtlGstk1Gstm1FynGsrSqstm1Txn1Slc7a11FosMafgAkr7a2PrkcgPsmc4Smarca4Mapk9CrebbpPsmc2Aldh3a1Ep300Cacng6Abcc1Tp53PrkcePsmc3Rbx1JunMap3k5ROSNqo2Pik3c2bFmo1Nfe2l2PrkcaRrasPgdPik3c2aUbe2kTaldo1Gsta3Brca1Prkd3Slc35a2Cdkn1aBach1Keap1LdhbGsta2Gsta1Pik3cgCbr1Acta1NrasAldoaAkr1b10Mapk7Pik3r5Sod2Map2k5Nqo1KrasSqstm1Map2k7PrkczActg1Scarb1Map2k2MaffTxnrd1Mapk14Mgst1Pik3caRaf1Me1ActbAtf4Atf4Hmox1Dhcr7Cdc34Pik3c2gDnajb4GclmGpx2Gsto2HrasPik3c3AtmAox1PrkciPik3r3Mgst3Prdx1DRUGS METABOLISMUV RADIATIONRESPIRATORY BURSTINFLAMATORY CITOKINESAbcc4Gstt2Pik3r1PrkchGstm4Pik3r6PrkcqFosGstp1Yy1Slc35b1Psmc6Map2k1UgdhG6pdMgst2Pmf1Akt1Sod3Gsk3bDnajc5Actg2Cul3Bach1Psmc1Pik3r4Gsta4Sod1GlutathioneGstm3Gsto1Rras2Slc1a4Map2k6Ptgr1Eif2ak3Map3k7Actc1Acta2Akr7a3Mapk3GclcPrkcd***Psmc5GssMdm2Herpud1Map3k1Gstm2Abcc3Hsp90ab1Keap1Actc1Acta2ActbActa1Actg1Actg2Nfe2l2Nfe2l2


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
125515view02:34, 24 February 2023AlexanderPicoadded description
110698view14:01, 28 May 2020EgonwAdded missing @Type annotation
110697view14:00, 28 May 2020EgonwAdded missing @Type annotation
106970view13:43, 17 September 2019MaintBotHMDB identifier normalization
94539view08:01, 21 September 2017EgonwModified title
91468view03:27, 4 March 2017Richard10Modified title
82999view04:24, 17 November 2015Mkutmonfix outdated identifiers
78474view10:28, 7 January 2015MaintBotadded missing graphIds
71118view00:41, 7 October 2013Richard10Update
71117view00:35, 7 October 2013Richard10Periodical save, work in progress
69742view09:13, 11 July 2013EgonwAdded a ChEBI id for ROS.
68372view03:37, 4 July 2013Richard10progress
68135view11:56, 1 July 2013DdiglesOntology Term : 'nuclear factor, erythroid derived 2, like 2 signaling pathway' added !
58962view18:36, 21 February 2013MaintBotUpdated Ensembl data source
56342view20:39, 5 January 2013MaintBotModified categories
54389view21:57, 28 November 2012Richard10Specify description
54337view03:03, 28 November 2012Richard10Specify description
54336view03:00, 28 November 2012Richard10Periodical save, work in progress
54335view02:57, 28 November 2012Richard10Specify description
54334view02:49, 28 November 2012Richard10New pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
***GeneProduct
Abcc1GeneProduct3112 (RGD)
Abcc3GeneProduct71101 (RGD)
Abcc4GeneProduct620266 (RGD)
Acta1GeneProduct2025 (RGD)
Acta2GeneProduct81633 (Entrez Gene)
ActbGeneProduct628837 (RGD)
Actc1GeneProduct2026 (RGD)
Actg1GeneProduct1304556 (RGD)
Actg2GeneProduct2027 (RGD)
Akr1a1GeneProduct68346 (RGD)
Akr1b10GeneProduct1308277 (RGD)
Akr7a2GeneProduct620311 (RGD)
Akr7a3GeneProduct628635 (RGD)
Akt1GeneProduct2081 (RGD)
Aldh3a1GeneProduct2088 (RGD)
AldoaGeneProduct2089 (RGD)
Aox1GeneProduct54349 (Entrez Gene)
Atf4GeneProduct621863 (RGD)
AtmGeneProduct1593265 (RGD)
Bach1GeneProduct1306693 (RGD)
Bard1GeneProduct621072 (RGD)
Brca1GeneProduct2218 (RGD)
Cacng6GeneProduct628806 (RGD)
Cbr1GeneProduct2286 (RGD)
Cdc34GeneProduct1305411 (RGD)
Cdkn1aGeneProduct69328 (RGD)
CebpaGeneProduct2326 (RGD)
CrebbpGeneProduct2401 (RGD)
Cul3GeneProduct1308190 (RGD)
DRUGS METABOLISM

UV RADIATION RESPIRATORY BURST

INFLAMATORY CITOKINES
Dhcr7GeneProduct621769 (RGD)
Dnajb4GeneProduct1305826 (RGD)
Dnajb9GeneProduct3070 (RGD)
Dnajc5GeneProduct620516 (RGD)
Eif2ak3GeneProduct70884 (RGD)
Ep300GeneProduct170915 (Entrez Gene)
Ephx1GeneProduct2557 (RGD)
Fmo1GeneProduct2622 (RGD)
FosGeneProduct2626 (RGD)
Fosl1GeneProduct2627 (RGD)
Fth1GeneProduct2635 (RGD)
FtlGeneProduct61813 (RGD)
FynGeneProduct2641 (RGD)
G6pdGeneProduct2645 (RGD)
GclcGeneProduct619868 (RGD)
GclmGeneProduct619871 (RGD)
GlutathioneMetaboliteHMDB00125 (HMDB)
Gpx2GeneProduct727780 (RGD)
Gsk3bGeneProduct70982 (RGD)
GsrGeneProduct621747 (RGD)
GssGeneProduct2752 (RGD)
Gsta1GeneProduct2753 (RGD)
Gsta2GeneProduct2754 (RGD)
Gsta3GeneProduct24421 (Entrez Gene)
Gsta4GeneProduct1309970 (RGD)
Gstk1GeneProduct735188 (RGD)
Gstm1GeneProduct2755 (RGD)
Gstm2GeneProduct2756 (RGD)
Gstm3GeneProduct620381 (RGD)
Gstm4GeneProduct1565825 (RGD)
Gstm5GeneProduct61964 (RGD)
Gsto1GeneProduct70952 (RGD)
Gsto2GeneProduct1310764 (RGD)
Gstp1GeneProduct2758 (RGD)
Gstt1GeneProduct2765 (RGD)
Gstt2GeneProduct29487 (Entrez Gene)
Herpud1GeneProduct620818 (RGD)
Hmox1GeneProduct2806 (RGD)
HrasGeneProduct293621 (Entrez Gene)
Hsp90ab1GeneProduct1303075 (RGD)
JunGeneProduct2943 (RGD)
Keap1GeneProduct621619 (RGD)
KrasGeneProduct2981 (RGD)
LdhbGeneProduct2997 (RGD)
MaffGeneProduct1309531 (RGD)
MafgGeneProduct619953 (RGD)
MafkGeneProduct628633 (RGD)
Map2k1GeneProduct70495 (RGD)
Map2k2GeneProduct61888 (RGD)
Map2k3GeneProduct1306620 (RGD)
Map2k5GeneProduct29568 (Entrez Gene)
Map2k6GeneProduct620666 (RGD)
Map2k7GeneProduct1560043 (RGD)
Map3k1GeneProduct620966 (RGD)
Map3k5GeneProduct1306431 (RGD)
Map3k7GeneProduct1309438 (RGD)
Mapk14GeneProduct70496 (RGD)
Mapk1GeneProduct70500 (RGD)
Mapk3GeneProduct3046 (RGD)
Mapk7GeneProduct621505 (RGD)
Mapk8GeneProduct116554 (Entrez Gene)
Mapk9GeneProduct628847 (RGD)
Mdm2GeneProduct1305332 (RGD)
Me1GeneProduct3074 (RGD)
Mgst1GeneProduct70927 (RGD)
Mgst2GeneProduct1311218 (RGD)
Mgst3GeneProduct1306373 (RGD)
MrasGeneProduct3111 (RGD)
Nfe2l2GeneProduct620360 (RGD)
Nqo1GeneProduct2503 (RGD)
Nqo2GeneProduct1303320 (RGD)
NrasGeneProduct3205 (RGD)
PROTEOSOME

DEGRADATION

OF NFE2L2
PgdGeneProductENSRNOG00000023562 (Ensembl Rat)
Pik3c2aGeneProduct1310389 (RGD)
Pik3c2bGeneProduct1306541 (RGD)
Pik3c2gGeneProduct620231 (RGD)
Pik3c3GeneProduct620899 (RGD)
Pik3caGeneProduct170911 (Entrez Gene)
Pik3cbGeneProduct620917 (RGD)
Pik3cdGeneProduct1310990 (RGD)
Pik3cg GeneProduct1306468 (RGD)
Pik3r1GeneProduct25513 (Entrez Gene)
Pik3r2GeneProduct68341 (RGD)
Pik3r3GeneProduct621042 (RGD)
Pik3r4GeneProduct363131 (Entrez Gene)
Pik3r5GeneProduct1563261 (RGD)
Pik3r6GeneProduct1560850 (RGD)
Pmf1GeneProduct1584694 (RGD)
Prdx1GeneProduct620039 (RGD)
PrkcaGeneProduct3395 (RGD)
PrkcbGeneProduct25023 (Entrez Gene)
PrkcdGeneProduct67383 (RGD)
PrkceGeneProduct61925 (RGD)
PrkcgGeneProduct3397 (RGD)
PrkchGeneProduct621888 (RGD)
PrkciGeneProduct620961 (RGD)
PrkcqGeneProduct620968 (RGD)
PrkczGeneProduct3399 (RGD)
Prkd1GeneProduct620964 (RGD)
Prkd3GeneProduct1310236 (RGD)
Psmc1GeneProduct621097 (RGD)
Psmc2GeneProduct3428 (RGD)
Psmc3GeneProduct61905 (RGD)
Psmc4GeneProduct621102 (RGD)
Psmc5GeneProduct708376 (RGD)
Psmc6GeneProduct1308825 (RGD)
Ptgr1GeneProduct621195 (RGD)
ROSMetabolite
Raf1GeneProduct3531 (RGD)
Rbx1GeneProduct1308453 (RGD)
RrasGeneProduct1311443 (RGD)
Rras2GeneProduct1310793 (RGD)
Scarb1GeneProduct2302 (RGD)
Slc1a4GeneProduct735146 (RGD)
Slc2a1GeneProduct3704 (RGD)
Slc35a2GeneProduct2293497 (RGD)
Slc35b1GeneProduct727783 (RGD)
Slc7a11GeneProduct1309275 (RGD)
Smarca4GeneProduct621728 (RGD)
Sod1GeneProduct3731 (RGD)
Sod2GeneProduct3732 (RGD)
Sod3GeneProduct3733 (RGD)
Sqstm1GeneProduct113894 (Entrez Gene)
Taldo1GeneProduct620674 (RGD)
Tp53GeneProduct3889 (RGD)
Txn1GeneProduct621157 (RGD)
Txnrd1GeneProduct61959 (RGD)
Ub2GeneProduct
UbbGeneProduct192255 (Entrez Gene)
Ube2kGeneProduct1311626 (RGD)
UgdhGeneProduct621879 (RGD)
Usp14GeneProduct1311825 (RGD)
VcpGeneProduct621595 (RGD)
Yy1GeneProduct3982 (RGD)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2376"
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