Methylation (Gallus gallus)

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1, 2SAM synthesis (co-substrate)S-methylationO-methylationN-methylationMAT1AS-AdenosylhomocysteineS-AdenosylhomocysteineS-AdenosylmethionineMAT2BINMTS-methylated substrateMAT2AATPPhosphateS-AdenosylhomocysteineO-methylated substrateTPMTPNMTSubstrateN-methylated substrateS-AdenosylmethioninePhosphateS-AdenosylmethionineCOMTNNMTL-MethionineHNMT


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP704(r30265) with a 55% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Testa B, Kramer SD; ''The biochemistry of drug metabolism--an introduction: part 4. reactions of conjugation and their enzymes.''; Chem Biodivers, 2008 PubMed Europe PMC Scholia
  2. Weinshilboum RM; ''Pharmacogenomics: catechol O-methyltransferase to thiopurine S-methyltransferase.''; Cell Mol Neurobiol, 2006 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118251view12:04, 26 May 2021EweitzModified title
106110view12:01, 16 August 2019MaintBotHMDB identifier normalization
68791view17:13, 8 July 2013MaintBotUpdated to 2013 gpml schema
58768view22:15, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40922view22:51, 1 March 2011MaintBotRemoved redundant pathway information and comments
33853view17:43, 9 December 2009MaintBotAutomatic update of empty xrefs
33448view14:59, 30 November 2009MaintBotRemoved group label
30334view20:47, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATPMetaboliteHMDB00538 (HMDB)
COMTGeneProductENSGALG00000002024 (Ensembl)
HNMTGeneProductENSGALG00000012377 (Ensembl)
INMTGeneProduct
L-MethionineMetaboliteHMDB00696 (HMDB)
MAT1AGeneProductENSGALG00000002479 (Ensembl)
MAT2AGeneProduct
MAT2BGeneProductENSGALG00000001750 (Ensembl)
N-methylated substrateMetabolite
NNMTGeneProduct
O-methylated substrateMetabolite
PNMTGeneProduct776803 (Entrez Gene)
PhosphateMetaboliteHMDB01429 (HMDB)
S-AdenosylhomocysteineMetaboliteHMDB00939 (HMDB)
S-AdenosylmethionineMetaboliteHMDB01185 (HMDB)
S-methylated substrateMetabolite
SubstrateMetabolite
TPMTGeneProductENSGALG00000012687 (Ensembl)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP765"
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