Oxidation by cytochrome P450 (Bos taurus)

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1Cytochrome P450 genesNB5R4_BOVINCYP27B1CYP2F1CYP3A43H2OCP51A_BOVINCP2U1_BOVINO2Fe2+CYP2G1PQ0P5F6_BOVINNP_001029545.1CYP2A6Q0P5F6_BOVINCYP19A1CP20A_BOVINFe2+CYB5_BOVINIPI00695412.4CYP4F8Fe2+SubstrateCYP4F12NAD+CYP4A22Fe3+CYPCYP3A7CYP4F2CYPCYP2C9CYP2A13CYP2C8IPI00701018.4CYP11B2A9CSS1_BOVINNB5R1_BOVINCYP4Z1NP_001069607.1CP11A_BOVINNP_001069735.1Fe3+CYP3A4activated O2SubstrateCYP4F11Fe2+CP51A_BOVINCP2E1_BOVINQ0P5F6_BOVINNP_001069670.1IPI00698655.1CYP2C18NB5R3_BOVINIPI00709424.4CYB5_BOVINIPI00904186.1CYP2D6NM_001075173.1NADP+CYP2C19CYP46A1CYB5_BOVINSubstrateIPI00905203.2NP_001093836.1IPI00713683.4IPI00701497.5IPI00704129.5NP_001076882.1CYPCYPNADPHNP_001092408.1CYP4F22SubstrateNCPR_BOVINQ95KN3_BOVINNADHCYP4A11SubstrateCYP2J2CYP17A1Substrate-OHA6H748_BOVINA6QPJ8_BOVINIPI00700522.1O2Fe3+CYP11B1CYP3A5CYP2A7Fe3+CP21A_BOVINCYP


Description

Oxidation of a substrate by Cytochrome P450. Adapted from Niesink et al., Chapter 3, p. 47-48.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP43(r29608) with a 50% conversion rate.

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Ontology Terms

 

Bibliography

  1. Niesink, R.J.M, Vries, de, J., Hollinger, M.A.; ''Toxicology; Principles and Applications''; , 1996

History

View all...
CompareRevisionActionTimeUserComment
125262view12:14, 31 January 2023LarsgwAdd ISBN to publication
117586view11:24, 21 May 2021EweitzModified title
113856view06:17, 2 December 2020EgonwAdded missing DataNode types
107055view14:14, 17 September 2019MaintBotChEBI identifier normalization
105991view11:51, 16 August 2019MaintBotHMDB identifier normalization
102463view05:50, 24 December 2018EgonwFixed a data source.
101941view06:26, 19 November 2018EgonwReplaced Wikipedia with Wikidata identifiers.
80775view15:25, 30 June 2015Mkutmonhomology conversion
73517view23:31, 29 January 2014KhanspersModified title
72372view09:55, 13 November 2013EgonwFixed the PubChem-compound database name.
71405view19:01, 17 October 2013MaintBotAutomated update of data sources
70162view00:26, 13 July 2013AlexanderPicoModified title
63345view22:21, 9 May 2013MaintBotUpdated to 2013 gpml schema
58812view23:18, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40519view19:29, 1 March 2011MaintBotRemoved redundant pathway information and comments
33762view00:03, 9 December 2009MaintBotAutomatic update of empty xrefs
31710view11:52, 14 August 2009MaintBotFixed group labels
30646view22:32, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A6H748_BOVINGeneProductENSBTAG00000000085 (Ensembl)
A6QPJ8_BOVINGeneProductENSBTAG00000021118 (Ensembl)
A9CSS1_BOVINGeneProductENSBTAG00000010531 (Ensembl)
CP11A_BOVINGeneProductENSBTAG00000006934 (Ensembl)
CP20A_BOVINGeneProductENSBTAG00000000851 (Ensembl)
CP21A_BOVINGeneProductENSBTAG00000001443 (Ensembl)
CP2E1_BOVINGeneProductENSBTAG00000018365 (Ensembl)
CP2U1_BOVINGeneProductENSBTAG00000012972 (Ensembl)
CP51A_BOVINGeneProductENSBTAG00000001992 (Ensembl)
CYB5_BOVINGeneProductENSBTAG00000012012 (Ensembl)
CYPGeneProduct
CYP11B1GeneProduct282422 (Entrez Gene)
CYP11B2GeneProduct282423 (Entrez Gene)
CYP17A1GeneProduct782561 (Entrez Gene)
CYP19A1GeneProduct281740 (Entrez Gene)
CYP27B1GeneProductENSBTAG00000016906 (Ensembl)
CYP2A13GeneProduct
CYP2A6GeneProduct
CYP2A7GeneProduct
CYP2C18GeneProduct535243 (Entrez Gene)
CYP2C19GeneProduct510380 (Entrez Gene)
CYP2C8GeneProduct
CYP2C9GeneProduct
CYP2D6GeneProduct282211 (Entrez Gene)
CYP2F1GeneProduct
CYP2G1PGeneProduct
CYP2J2GeneProduct521656 (Entrez Gene)
CYP3A43GeneProduct
CYP3A4GeneProduct507988 (Entrez Gene)
CYP3A5GeneProduct526682 (Entrez Gene)
CYP3A7GeneProduct
CYP46A1GeneProduct506438 (Entrez Gene)
CYP4A11GeneProduct511890 (Entrez Gene)
CYP4A22GeneProduct516085 (Entrez Gene)
CYP4F11GeneProduct
CYP4F12GeneProduct
CYP4F22GeneProduct
CYP4F2GeneProduct507615 (Entrez Gene)
CYP4F8GeneProduct
CYP4Z1GeneProduct
Fe2+Metabolite29033 (ChEBI)
Fe3+Metabolite29034 (ChEBI)
H2OMetabolite
IPI00695412.4GeneProductENSBTAG00000015647 (Ensembl)
IPI00698655.1GeneProductENSBTAG00000005287 (Ensembl)
IPI00700522.1GeneProductENSBTAG00000012212 (Ensembl)
IPI00701018.4GeneProductENSBTAG00000016142 (Ensembl)
IPI00701497.5GeneProductENSBTAG00000017701 (Ensembl)
IPI00704129.5GeneProductENSBTAG00000039319 (Ensembl)
IPI00709424.4GeneProductENSBTAG00000001299 (Ensembl)
IPI00713683.4GeneProductENSBTAG00000002765 (Ensembl)
IPI00904186.1GeneProductENSBTAG00000039973 (Ensembl)
IPI00905203.2GeneProductENSBTAG00000038275 (Ensembl)
NAD+Metabolite15846 (ChEBI)
NADHMetabolite16908 (ChEBI)
NADP+Metabolite18009 (ChEBI)
NADPHMetabolite16474 (ChEBI)
NB5R1_BOVINGeneProductENSBTAG00000019927 (Ensembl)
NB5R3_BOVINGeneProductENSBTAG00000016516 (Ensembl)
NB5R4_BOVINGeneProductENSBTAG00000013591 (Ensembl)
NCPR_BOVINGeneProductENSBTAG00000017082 (Ensembl)
NM_001075173.1GeneProductENSBTAG00000003871 (Ensembl)
NP_001029545.1GeneProductENSBTAG00000021263 (Ensembl)
NP_001069607.1GeneProductENSBTAG00000034106 (Ensembl)
NP_001069670.1GeneProductENSBTAG00000011976 (Ensembl)
NP_001069735.1GeneProductENSBTAG00000010419 (Ensembl)
NP_001076882.1GeneProductENSBTAG00000013489 (Ensembl)
NP_001092408.1GeneProductENSBTAG00000003632 (Ensembl)
NP_001093836.1GeneProductENSBTAG00000018240 (Ensembl)
O2Metabolite977 (PubChem)
Q0P5F6_BOVINGeneProductENSBTAG00000002412 (Ensembl)
Q95KN3_BOVINGeneProductENSBTAG00000001021 (Ensembl)
SubstrateGeneProduct
Substrate-OHGeneProduct
activated O2Metabolite

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1077"
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