NAD salvage pathway III (Escherichia coli)

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1-9nadRAdenosinetriphosphateNicotinamideribosideNicotinamide ribotideHydrogen IonADPHydrogen IonAdenosinetriphosphatePyrophosphatenadRNAD


Description

A subpathway of NAD salvage pathway II. Where nicotinamide is converted to nicotinamide rotide and then to NAD

Comments

 
source: http://biocyc.org/ECOLI/NEW-IMAGE?type=PATHWAY&object=PWY3O-4106&detail-level=3

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Quality Tags

Ontology Terms

 

Bibliography

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  1. Sánchez-Alcón MD, Pérez Garrigues H, Vílchez J, Casanova B, Morera C; ''[The study of deafness in patients with facioscapulohumeral dystrophy].''; Acta Otorrinolaringol Esp, 1994 PubMed Europe PMC Scholia
  2. Bieganowski P, Brenner C; ''Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans.''; Cell, 2004 PubMed Europe PMC Scholia
  3. Lin SJ, Guarente L; ''Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease.''; Curr Opin Cell Biol, 2003 PubMed Europe PMC Scholia
  4. Kurnasov OV, Polanuyer BM, Ananta S, Sloutsky R, Tam A, Gerdes SY, Osterman AL; ''Ribosylnicotinamide kinase domain of NadR protein: identification and implications in NAD biosynthesis.''; J Bacteriol, 2002 PubMed Europe PMC Scholia
  5. Ostrowski EA, Woods RJ, Lenski RE; ''The genetic basis of parallel and divergent phenotypic responses in evolving populations of Escherichia coli.''; Proc Biol Sci, 2008 PubMed Europe PMC Scholia
  6. Gerasimova AV, Gelfand MS; ''Evolution of the NadR regulon in Enterobacteriaceae.''; J Bioinform Comput Biol, 2005 PubMed Europe PMC Scholia
  7. Raffaelli N, Lorenzi T, Mariani PL, Emanuelli M, Amici A, Ruggieri S, Magni G; ''The Escherichia coli NadR regulator is endowed with nicotinamide mononucleotide adenylyltransferase activity.''; J Bacteriol, 1999 PubMed Europe PMC Scholia
  8. Lin SJ, Ford E, Haigis M, Liszt G, Guarente L; ''Calorie restriction extends yeast life span by lowering the level of NADH.''; Genes Dev, 2004 PubMed Europe PMC Scholia
  9. Tritz GJ, Chandler JL; ''Recognition of a gene involved in the regulation of nicotinamide adenine dinucleotide biosynthesis.''; J Bacteriol, 1973 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
106101view12:01, 16 August 2019MaintBotHMDB identifier normalization
62866view10:30, 3 May 2013CizarModified description
62268view22:22, 26 April 2013AlexanderPicoOntology Term : 'pyridine nucleotide biosynthetic pathway' added !
62257view21:57, 26 April 2013AlexanderPicoOntology Term : 'NAD biosynthetic pathway' added !
62256view21:57, 26 April 2013AlexanderPicoOntology Term : 'purine salvage pathway' added !
62253view21:53, 26 April 2013AlexanderPicoModified categories
61954view07:43, 22 April 2013Cizargrouped and aligned the metabolites
61799view10:00, 19 April 2013CizarModified description
61798view09:55, 19 April 2013Cizaradded references
61797view09:51, 19 April 2013CizarNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ADPMetaboliteHMDB01341 (HMDB)
Adenosine triphosphateMetaboliteHMDB00538 (HMDB)
Hydrogen IonMetaboliteHMDB59597 (HMDB)
NADMetaboliteHMDB00902 (HMDB)
Nicotinamide ribosideMetaboliteHMDB00855 (HMDB)
Nicotinamide ribotideMetaboliteHMDB00229 (HMDB)
PyrophosphateMetaboliteHMDB00250 (HMDB)
nadRGeneProductEBESCG00000001171 (Ensembl)

Annotated Interactions

No annotated interactions
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