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spontaneous Water NADP TDO2 AFMID Nicotinic acid mononucleotide Water Oxygen Adenosine triphosphate Hydrogen Ion L-Alanine L-Kynurenine NADSYN1 L-Tryptophan NMNAT1 Nicotinic acid adenine dinucleotide 3-Hydroxyanthranilic acid NAD Phosphoribosyl pyrophosphate NADPH pyrophosphate Carbon dioxide Water KMO QPRT Formic acid Pyrophosphate KYNU 2-Amino-3-carboxymuconic acid semialdehyde Quinolinic acid L-Glutamic acid Adenosine triphosphate HAAO N'-Formylkynurenine L-Glutamine Pyrophosphate Adenosine monophosphate L-3-Hydroxykynurenine Hydrogen Ion Water Hydrogen Ion Hydrogen Ion Hydrogen Ion Hydrogen Ion Oxygen Hydrogen Ion Water Hydrogen Ion Hydrogen Ion Hydrogen Ion Oxygen Hydrogen Ion Hydrogen Ion
Description
This is a general pathway for NAD biosynthesis in eukaryotes, where tryptophan is eventually converted into NAD. Though through recent studies it seems that NAD biosynthesis through tryptophan also occurs in some prokaryotes.
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