Alpha 6 beta 4 signaling pathway (Bos taurus)

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DLaminin 2DGOCytoplasmPlasma membraneDNUECProteolytic cleavagePMAccession Number: NetPath 1; cellmap:1DeubiquitinationDMethylationDeacetylationProteins in a complex interactionSumoylationMolecule in the pathwayPalmitoylationControlCY->NUAcetylationExtracellularEnzyme complexLaminin 1ERCYCY->NUDemethylationInhibitionDesumoylationMitochondrionEndosome(Protein-protein interaction)DAutophosphorylationReceptorEndoplasmic reticulumCY->NUTranslocationGene SymbolLaminin 5CY->PMDDENRecruitmentNucleusLaminin 4ActivationMTGlycosylationLaminin 10DMolecular AssociationReaction through unknown mechanisms/moleculesGolgi apparatusUbiquitinationLigandLaminin 11DephosphorylationDPhosphorylationITGB4LAMA3EIF4EBP1DSTSMAD2LAMB3YWHAHPIK3CBARSHC1ITGA6PIK3CDSMAD2RPSARTKNLAMA2LOC100139219ITGB4SMAD3FYNCD151PRKCALAMB1ITGB4EIF4EMST1RLAMC2IRS1ITGA6ITGA6YWHAELAMC1PIK3R1IRS2AKT1ITGA6PIK3R2CASP3LAMC1SFNGRB2RHOAITGA6TP73PRKCDLAMA5COL17A1DSPPTK2LAMA1CDKN1AYES1LAMC1LAMC1VIMCLCA1EIF6EIF6ITGB4PIK3CGRHOAYWHAQYWHABMETNTN1LAMB1YWHAZLAMA5PAK1LAMB1ITGA6LAMA2CLCA2LAMB2PLEC1ITGB4SRCEGFRBADRAC1ERBB2PIK3CAITGB4ERBB2IPLAMC1ABL1LAMB2SMAD3MMP7PIK3R3


Description

No description

Comments

GenMAPP notes 
NetPath 13: IL-1 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP244(r21193) with a 86% conversion rate.

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Ontology Terms

 

Bibliography

  1. Kandasamy K, Mohan SS, Raju R, Keerthikumar S, Kumar GS, Venugopal AK, Telikicherla D, Navarro JD, Mathivanan S, Pecquet C, Gollapudi SK, Tattikota SG, Mohan S, Padhukasahasram H, Subbannayya Y, Goel R, Jacob HK, Zhong J, Sekhar R, Nanjappa V, Balakrishnan L, Subbaiah R, Ramachandra YL, Rahiman BA, Prasad TS, Lin JX, Houtman JC, Desiderio S, Renauld JC, Constantinescu SN, Ohara O, Hirano T, Kubo M, Singh S, Khatri P, Draghici S, Bader GD, Sander C, Leonard WJ, Pandey A; ''NetPath: a public resource of curated signal transduction pathways.''; Genome Biol, 2010 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117858view10:13, 23 May 2021EweitzModified title
115939view08:14, 21 March 2021EgonwCopied the NetPath paper into the literature list
115932view08:08, 21 March 2021EgonwModified description
85044view09:26, 10 April 2016EgonwReplaced a mim-conversion with mim-binding (protein-protein interaction).
80902view15:30, 30 June 2015Mkutmonhomology conversion
79846view07:19, 19 April 2015EgonwReplaced "Ensemble Cow" with "Ensembl".
79152view04:55, 6 March 2015MaintBotUpdated conversion from Hs
63396view00:04, 10 May 2013MaintBotUpdated to 2013 gpml schema
40569view19:32, 1 March 2011MaintBotRemoved redundant pathway information and comments
33807view00:19, 9 December 2009MaintBotAutomatic update of empty xrefs
31639view22:25, 13 August 2009MaintBotFixed text labels
30554view22:01, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ABL1GeneProduct540876 (Entrez Gene)
AKT1GeneProduct280991 (Entrez Gene)
ARGeneProduct280675 (Entrez Gene)
BADGeneProduct615013 (Entrez Gene)
CASP3GeneProduct408016 (Entrez Gene)
CD151GeneProduct523328 (Entrez Gene)
CDKN1AGeneProduct513497 (Entrez Gene)
CLCA1GeneProduct507643 (Entrez Gene)
CLCA2GeneProduct534256 (Entrez Gene)
COL17A1GeneProduct513804 (Entrez Gene)
DSPGeneProduct514360 (Entrez Gene)
DSTGeneProduct535297 (Entrez Gene)
EGFRGeneProduct407217 (Entrez Gene)
EIF4EGeneProduct281751 (Entrez Gene)
EIF4EBP1GeneProduct509613 (Entrez Gene)
EIF6GeneProduct286811 (Entrez Gene)
ERBB2GeneProduct
ERBB2IPGeneProduct512866 (Entrez Gene)
FYNGeneProduct527263 (Entrez Gene)
GRB2GeneProduct535298 (Entrez Gene)
IRS1GeneProduct538598 (Entrez Gene)
IRS2GeneProduct
ITGA6GeneProduct535043 (Entrez Gene)
ITGB4GeneProduct506995 (Entrez Gene)
LAMA1GeneProduct506387 (Entrez Gene)
LAMA2GeneProduct
LAMA3GeneProduct532965 (Entrez Gene)
LAMA5GeneProduct506751 (Entrez Gene)
LAMB1GeneProduct520030 (Entrez Gene)
LAMB2GeneProduct
LAMB3GeneProduct529939 (Entrez Gene)
LAMC1GeneProduct532572 (Entrez Gene)
LAMC2GeneProduct511043 (Entrez Gene)
LOC100139219GeneProduct100139219 (Entrez Gene)
METGeneProduct280855 (Entrez Gene)
MMP7GeneProduct286794 (Entrez Gene)
MST1RGeneProduct525504 (Entrez Gene)
NTN1GeneProduct522767 (Entrez Gene)
PAK1GeneProduct533729 (Entrez Gene)
PIK3CAGeneProduct282306 (Entrez Gene)
PIK3CBGeneProduct517948 (Entrez Gene)
PIK3CDGeneProduct504531 (Entrez Gene)
PIK3CGGeneProduct530001 (Entrez Gene)
PIK3R1GeneProduct282307 (Entrez Gene)
PIK3R2GeneProduct282308 (Entrez Gene)
PIK3R3GeneProduct286865 (Entrez Gene)
PLEC1GeneProduct
PRKCAGeneProduct282001 (Entrez Gene)
PRKCDGeneProduct505708 (Entrez Gene)
PTK2GeneProduct506270 (Entrez Gene)
RAC1GeneProduct281440 (Entrez Gene)
RHOAGeneProduct338049 (Entrez Gene)
RPSAGeneProduct281898 (Entrez Gene)
RTKNGeneProduct539691 (Entrez Gene)
SFNGeneProduct528453 (Entrez Gene)
SHC1GeneProduct507196 (Entrez Gene)
SMAD2GeneProduct516010 (Entrez Gene)
SMAD3GeneProduct515125 (Entrez Gene)
SRCGeneProduct535742 (Entrez Gene)
TP73GeneProduct515105 (Entrez Gene)
VIMGeneProduct280955 (Entrez Gene)
YES1GeneProduct507632 (Entrez Gene)
YWHABGeneProduct286863 (Entrez Gene)
YWHAEGeneProduct282125 (Entrez Gene)
YWHAHGeneProduct282126 (Entrez Gene)
YWHAQGeneProduct768311 (Entrez Gene)
YWHAZGeneProduct287022 (Entrez Gene)

Annotated Interactions

No annotated interactions
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