Metapathway biotransformation (Bos taurus)

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N-acetyltransferasesElectrophilesOxidationAmino acid acyl transferasesSulfotransferasesAmino acid conjugationAcetylationCytochrome P450SulfationGlutathione transferasesNucleophilesGlutathione reductaseMethylationGlutathione peroxidasesMethyltransferasesFlavin monooxygenasesGlucuronidationGlutathione conjugationGlutathione synthetaseGlucuronosyltransferasesEpoxide hydrolasesAldo-keto reductasesReductionHydrolysisCYP2A7IPI00903985.1IPI00906116.1NP_001091500.1IPI00686912.3GSTT2BCOMT_BOVINGSTT1G3ST4_BOVINIPI00702562.3GSTP1_BOVINIPI00692810.3GSTA5GSTT2IPI00697335.1GSTM1CYP4F11NP_001069683.1IPI00698855.3HNMT_BOVINIPI00905203.2CHST8NP_001068630.1ST1A1_BOVINCYP4Z1IPI00693768.3CYP4F22GLYATL1SULT1C4IPI00705496.1NNMTAKR7A3MGST2_BOVINUGT1A3IPI00688142.3NP_001077117.1IPI00689284.1CYP450SULT2B1IPI00705153.2Substrate-GlGSTA4_BOVINIPI00695412.4NP_001071429.1NAT14_BOVINIPI00716958.3ST1E1_BOVINUGT2B15CYP11B1GLYATCYP3A4NP_001040025.1NP_001069607.1GPX1_BOVINNP_001092414.1NP_001069154.1CYP2A6IPI00700522.1NP_001069986.1GPX4_BOVINNP_001069590.1A9CSS1_BOVINCHST9IPI00709424.4AK1A1_BOVINNAT8NP_001069735.1SULT2A1CYP2C18IPI00688083.3XR_027890.2NP_001069002.1Substrate-SHSulfotransferaseNP_001096716.1IPI00716297.1CYP4F2CYP3A5AKR1B1TPMT_BOVINCP51A_BOVINARY1_BOVINMGST1_BOVINNP_777187.1CYP4F8LOC515352UGT2B28ST1A1_BOVINIPI00709378.3GSTA3CP20A_BOVINGSTM4UGT1A7ST1B1_BOVING3ST1_BOVINIPI00708458.2NAT13_BOVINSULT1C2NP_001029545.1AKR1C4NP_001095549.1G3ST3_BOVINIPI00701497.5IPI00695153.3Substrate-NH2Xenobiotic substrateIPI00694081.4NP_001069613.1NDST2_BOVINIPI00687876.3CYP2C9Glutathione transferaseARY1_BOVINST1A1_BOVINUGT2A2IPI00698655.1FMO3GSHB_BOVINCYP2J2AKR7A2MGST3_BOVINA6QPJ8_BOVINCYP21A2IPI00906608.1GPX2NP_001069670.1UGT1A6IPI00904186.1UGT2A1CP2E1_BOVINCP2U1_BOVINUGT2B7GPX3_BOVINCYP11B2Substrate-OHCYP2C19UGT2B11ST1A1_BOVINGSTM5CYP2D6UGT2B17NP_001094774.1IPI00710606.2CYP2A13Substrate-SO3HCHST14UGT1A10Q95KN3_BOVINIPI00699039.4AKR1C2HS3ST4CP11A_BOVINSubstrate-AcKCAB2_BOVINLOC614317GlucuronosyltransferaseSubstrate-SGMethyltransferaseFlavin monooxygenaseNP_001020506.1UGT2B4NP_001073084.1NP_001071381.1UGT1A5CYP2C8NP_001093836.1KCAB1_BOVINA6H748_BOVINSubstrate-AaUGT1A4CYP19A1NP_001092474.1NP_001029801.1NP_001092408.1IPI00704129.5HS3ST3A1NP_001095558.1IPI00693008.2GSTA1NM_001075173.1HS6ST2IPI00713683.4GSTA2IPI00693008.2Substrate-CH3IPI00726067.3Amino acid acyltransferaseN-acetyltransferaseGSTO1AKR1C1CYP4F12NP_001076882.1GSTM2UGT1A9Substrate=OUGT1A1Substrate-O-RNP_001091480.1HS3ST3B1CYP3A43CYP3A7CYP17A1NP_001075096.1GSTCD_BOVINCYP2F1Aldo-keto reductaseAKR1C3CYP46A1CYP27B1


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP702(r29945) with a 58% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
80841view15:28, 30 June 2015Mkutmonhomology conversion
70171view00:39, 13 July 2013AlexanderPicoModified title
63459view17:18, 10 May 2013MaintBotUpdated to 2013 gpml schema
58827view23:19, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
53460view18:40, 7 November 2012AndraAdded missing Entrez Gene Id's after RDF Tidy
40594view19:33, 1 March 2011MaintBotRemoved redundant pathway information and comments
33831view00:29, 9 December 2009MaintBotAutomatic update of empty xrefs
33196view18:19, 5 November 2009KhanspersModified categories
32487view12:45, 17 August 2009MaintBotFixed text labels
32182view12:32, 15 August 2009MaintBotFixed text labels
31652view11:37, 14 August 2009MaintBotFixed group labels
31185view19:28, 13 August 2009MaintBotFixed text labels
30575view22:07, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A6H748_BOVINGeneProductENSBTAG00000000085 (Ensembl)
A6QPJ8_BOVINGeneProductENSBTAG00000021118 (Ensembl)
A9CSS1_BOVINGeneProductENSBTAG00000010531 (Ensembl)
AK1A1_BOVINGeneProductENSBTAG00000000497 (Ensembl)
AKR1B1GeneProduct317748 (Entrez Gene)
AKR1C1GeneProduct
AKR1C2GeneProduct
AKR1C3GeneProduct782884 (Entrez Gene)
AKR1C4GeneProduct282138 (Entrez Gene)
AKR7A2GeneProduct511996 (Entrez Gene)
AKR7A3GeneProduct788425 (Entrez Gene)
ARY1_BOVINGeneProductENSBTAG00000016473 (Ensembl)
Aldo-keto reductaseGeneProduct
Amino acid acyltransferaseGeneProduct
CHST14GeneProduct511245 (Entrez Gene)
CHST8GeneProduct100271926 (Entrez Gene)
CHST9GeneProduct525909 (Entrez Gene)
COMT_BOVINGeneProductENSBTAG00000019516 (Ensembl)
CP11A_BOVINGeneProductENSBTAG00000006934 (Ensembl)
CP20A_BOVINGeneProductENSBTAG00000000851 (Ensembl)
CP2E1_BOVINGeneProductENSBTAG00000018365 (Ensembl)
CP2U1_BOVINGeneProductENSBTAG00000012972 (Ensembl)
CP51A_BOVINGeneProductENSBTAG00000001992 (Ensembl)
CYP11B1GeneProduct282422 (Entrez Gene)
CYP11B2GeneProduct282423 (Entrez Gene)
CYP17A1GeneProduct782561 (Entrez Gene)
CYP19A1GeneProduct281740 (Entrez Gene)
CYP21A2GeneProduct282425 (Entrez Gene)
CYP27B1GeneProductENSBTAG00000016906 (Ensembl)
CYP2A13GeneProduct
CYP2A6GeneProduct
CYP2A7GeneProduct
CYP2C18GeneProduct535243 (Entrez Gene)
CYP2C19GeneProduct510380 (Entrez Gene)
CYP2C8GeneProduct
CYP2C9GeneProduct
CYP2D6GeneProduct282211 (Entrez Gene)
CYP2F1GeneProduct
CYP2J2GeneProduct521656 (Entrez Gene)
CYP3A43GeneProduct
CYP3A4GeneProduct507988 (Entrez Gene)
CYP3A5GeneProduct526682 (Entrez Gene)
CYP3A7GeneProduct
CYP450GeneProduct
CYP46A1GeneProduct506438 (Entrez Gene)
CYP4F11GeneProduct
CYP4F12GeneProduct
CYP4F22GeneProduct
CYP4F2GeneProduct507615 (Entrez Gene)
CYP4F8GeneProduct
CYP4Z1GeneProduct
FMO3GeneProduct281167 (Entrez Gene)
Flavin monooxygenaseGeneProduct
G3ST1_BOVINGeneProductENSBTAG00000014232 (Ensembl)
G3ST3_BOVINGeneProductENSBTAG00000002772 (Ensembl)
G3ST4_BOVINGeneProductENSBTAG00000015017 (Ensembl)
GLYATGeneProduct281787 (Entrez Gene)
GLYATL1GeneProduct
GPX1_BOVINGeneProductENSBTAG00000004274 (Ensembl)
GPX2GeneProduct533088 (Entrez Gene)
GPX3_BOVINGeneProductENSBTAG00000043553 (Ensembl)
GPX4_BOVINGeneProductENSBTAG00000020778 (Ensembl)
GSHB_BOVINGeneProductENSBTAG00000003504 (Ensembl)
GSTA1GeneProduct777644 (Entrez Gene)
GSTA2GeneProduct
GSTA3GeneProduct768055 (Entrez Gene)
GSTA4_BOVINGeneProductENSBTAG00000004288 (Ensembl)
GSTA5GeneProduct521685 (Entrez Gene)
GSTCD_BOVINGeneProductENSBTAG00000013927 (Ensembl)
GSTM1GeneProduct783879 (Entrez Gene)
GSTM2GeneProduct615537 (Entrez Gene)
GSTM4GeneProduct
GSTM5GeneProduct
GSTO1GeneProduct785216 (Entrez Gene)
GSTP1_BOVINGeneProductENSBTAG00000003548 (Ensembl)
GSTT1GeneProduct517724 (Entrez Gene)
GSTT2GeneProduct2953 (Entrez Gene)
GSTT2BGeneProduct
GlucuronosyltransferaseGeneProduct
Glutathione transferaseGeneProduct
HNMT_BOVINGeneProductENSBTAG00000014432 (Ensembl)
HS3ST3A1GeneProduct521959 (Entrez Gene)
HS3ST3B1GeneProduct617069 (Entrez Gene)
HS3ST4GeneProduct
HS6ST2GeneProduct517768 (Entrez Gene)
IPI00686912.3GeneProductENSBTAG00000012998 (Ensembl)
IPI00687876.3GeneProductENSBTAG00000001144 (Ensembl)
IPI00688083.3GeneProductENSBTAG00000009093 (Ensembl)
IPI00688142.3GeneProductENSBTAG00000006157 (Ensembl)
IPI00689284.1GeneProductENSBTAG00000002803 (Ensembl)
IPI00692810.3GeneProductENSBTAG00000001658 (Ensembl)
IPI00693008.2GeneProductENSBTAG00000040000 (Ensembl)
IPI00693768.3GeneProductENSBTAG00000038369 (Ensembl)
IPI00694081.4GeneProductENSBTAG00000010644 (Ensembl)
IPI00695153.3GeneProductENSBTAG00000001448 (Ensembl)
IPI00695412.4GeneProductENSBTAG00000015647 (Ensembl)
IPI00697335.1GeneProductENSBTAG00000011014 (Ensembl)
IPI00698655.1GeneProductENSBTAG00000005287 (Ensembl)
IPI00698855.3GeneProductENSBTAG00000025760 (Ensembl)
IPI00699039.4GeneProductENSBTAG00000017595 (Ensembl)
IPI00700522.1GeneProductENSBTAG00000012212 (Ensembl)
IPI00701497.5GeneProductENSBTAG00000017701 (Ensembl)
IPI00702562.3GeneProductENSBTAG00000008707 (Ensembl)
IPI00704129.5GeneProductENSBTAG00000039319 (Ensembl)
IPI00705153.2GeneProductENSBTAG00000016685 (Ensembl)
IPI00705496.1GeneProductENSBTAG00000021408 (Ensembl)
IPI00708458.2GeneProductENSBTAG00000017391 (Ensembl)
IPI00709378.3GeneProductENSBTAG00000001692 (Ensembl)
IPI00709424.4GeneProductENSBTAG00000001299 (Ensembl)
IPI00710606.2GeneProductENSBTAG00000003131 (Ensembl)
IPI00713683.4GeneProductENSBTAG00000002765 (Ensembl)
IPI00716297.1GeneProductENSBTAG00000019249 (Ensembl)
IPI00716958.3GeneProductENSBTAG00000040290 (Ensembl)
IPI00726067.3GeneProductENSBTAG00000039065 (Ensembl)
IPI00903985.1GeneProductENSBTAG00000007654 (Ensembl)
IPI00904186.1GeneProductENSBTAG00000039973 (Ensembl)
IPI00905203.2GeneProductENSBTAG00000038275 (Ensembl)
IPI00906116.1GeneProductENSBTAG00000038084 (Ensembl)
IPI00906608.1GeneProductENSBTAG00000011584 (Ensembl)
KCAB1_BOVINGeneProductENSBTAG00000018465 (Ensembl)
KCAB2_BOVINGeneProductENSBTAG00000008125 (Ensembl)
LOC515352GeneProductENSBTAG00000030847 (Ensembl)
LOC614317GeneProductENSBTAG00000031364 (Ensembl)
MGST1_BOVINGeneProductENSBTAG00000008541 (Ensembl)
MGST2_BOVINGeneProductENSBTAG00000021779 (Ensembl)
MGST3_BOVINGeneProductENSBTAG00000010265 (Ensembl)
MethyltransferaseGeneProduct
N-acetyltransferaseGeneProduct
NAT13_BOVINGeneProductENSBTAG00000007784 (Ensembl)
NAT14_BOVINGeneProductENSBTAG00000019051 (Ensembl)
NAT8GeneProduct
NDST2_BOVINGeneProductENSBTAG00000012664 (Ensembl)
NM_001075173.1GeneProductENSBTAG00000003871 (Ensembl)
NNMTGeneProduct
NP_001020506.1GeneProductENSBTAG00000021987 (Ensembl)
NP_001029545.1GeneProductENSBTAG00000021263 (Ensembl)
NP_001029801.1GeneProductENSBTAG00000000140 (Ensembl)
NP_001040025.1GeneProductENSBTAG00000001842 (Ensembl)
NP_001068630.1GeneProductENSBTAG00000002974 (Ensembl)
NP_001069002.1GeneProductENSBTAG00000015241 (Ensembl)
NP_001069154.1GeneProductENSBTAG00000002706 (Ensembl)
NP_001069590.1GeneProductENSBTAG00000007449 (Ensembl)
NP_001069607.1GeneProductENSBTAG00000034106 (Ensembl)
NP_001069613.1GeneProductENSBTAG00000016968 (Ensembl)
NP_001069670.1GeneProductENSBTAG00000011976 (Ensembl)
NP_001069683.1GeneProductENSBTAG00000000188 (Ensembl)
NP_001069735.1GeneProductENSBTAG00000010419 (Ensembl)
NP_001069986.1GeneProductENSBTAG00000006273 (Ensembl)
NP_001071381.1GeneProductENSBTAG00000020898 (Ensembl)
NP_001071429.1GeneProductENSBTAG00000007316 (Ensembl)
NP_001073084.1GeneProductENSBTAG00000009839 (Ensembl)
NP_001075096.1GeneProductENSBTAG00000014940 (Ensembl)
NP_001076882.1GeneProductENSBTAG00000013489 (Ensembl)
NP_001077117.1GeneProductENSBTAG00000003721 (Ensembl)
NP_001091480.1GeneProductENSBTAG00000004328 (Ensembl)
NP_001091500.1GeneProductENSBTAG00000016747 (Ensembl)
NP_001092408.1GeneProductENSBTAG00000003632 (Ensembl)
NP_001092414.1GeneProductENSBTAG00000004040 (Ensembl)
NP_001092474.1GeneProductENSBTAG00000003073 (Ensembl)
NP_001093836.1GeneProductENSBTAG00000018240 (Ensembl)
NP_001094774.1GeneProductENSBTAG00000010841 (Ensembl)
NP_001095549.1GeneProductENSBTAG00000008778 (Ensembl)
NP_001095558.1GeneProductENSBTAG00000001582 (Ensembl)
NP_001096716.1GeneProductENSBTAG00000011387 (Ensembl)
NP_777187.1GeneProductENSBTAG00000026181 (Ensembl)
Q95KN3_BOVINGeneProductENSBTAG00000001021 (Ensembl)
ST1A1_BOVINGeneProductENSBTAG00000008635 (Ensembl)
ST1B1_BOVINGeneProductENSBTAG00000001249 (Ensembl)
ST1E1_BOVINGeneProductENSBTAG00000011952 (Ensembl)
SULT1C2GeneProduct783020 (Entrez Gene)
SULT1C4GeneProduct537919 (Entrez Gene)
SULT2A1GeneProduct533560 (Entrez Gene)
SULT2B1GeneProduct531192 (Entrez Gene)
Substrate-AaMetabolite
Substrate-AcMetabolite
Substrate-CH3Metabolite
Substrate-GlMetabolite
Substrate-NH2Metabolite
Substrate-O-RMetabolite
Substrate-OHMetabolite
Substrate-SGMetabolite
Substrate-SHMetabolite
Substrate-SO3HMetabolite
Substrate=OMetabolite
SulfotransferaseGeneProduct
TPMT_BOVINGeneProductENSBTAG00000019300 (Ensembl)
UGT1A10GeneProduct
UGT1A1GeneProduct751790 (Entrez Gene)
UGT1A3GeneProduct
UGT1A4GeneProduct
UGT1A5GeneProduct
UGT1A6GeneProduct286792 (Entrez Gene)
UGT1A7GeneProduct
UGT1A9GeneProduct
UGT2A1GeneProduct
UGT2A2GeneProduct
UGT2B11GeneProduct100138004 (Entrez Gene)
UGT2B15GeneProduct540544 (Entrez Gene)
UGT2B17GeneProduct540615 (Entrez Gene)
UGT2B28GeneProduct
UGT2B4GeneProduct615303 (Entrez Gene)
UGT2B7GeneProduct
XR_027890.2GeneProductENSBTAG00000007115 (Ensembl)
Xenobiotic substrateMetabolite

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1006"
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