G13 signaling pathway (Danio rerio)

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1CytokinesisG13Contraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber ContractionActivated Rho AActin PolymerizationDisassembly of ActinAnti-ApoptoticActin PolymerizationFilopodia FormationStress Fiber DisappearanceActin ReorganizationCell-Cell AdhesionMembrane Rufflingmapk10LOC561737cdc42lDKEY-40C11.1LOC560360wu:fb92a07PAK3MYBPHpik3r2waslarps6kb1LOC569144IQGAP2wu:fc83c01PKN1cfl2ARHGDIGDIAPH1SH3MD2ROCK1rock2aiqgap1gna13arhpn2CFL1PFN1CALM1zgc:153713p140 Sra-1ppp1cbarhgdigLOC559119pik3cdrac1limk1ARHGEF1wasbzgc:77231


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP524(r21780) with a 65% conversion rate.

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Ontology Terms

 

Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
116876view10:56, 15 May 2021EweitzModified title
95753view14:07, 19 January 2018MkutmonHomology conversion update
77431view12:09, 8 September 2014Mkutmonupdated gene labes and some xrefs
72021view12:41, 24 October 2013Mkutmonfixed unconnected lines
71517view19:22, 17 October 2013MaintBotAutomated update of data sources
68648view05:02, 6 July 2013MaintBotUpdated to 2013 gpml schema
67275view10:30, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
62789view16:32, 2 May 2013MaintBotUpdated UniProt data source
40816view22:17, 1 March 2011MaintBotRemoved redundant pathway information and comments
35426view10:54, 12 February 2010ThomasModified description
35425view10:53, 12 February 2010Thomasremoved braces, fixed labels, added literature
34204view21:29, 9 December 2009MaintBotAutomatic update of empty xrefs
32372view16:44, 15 August 2009MaintBotFixed text labels
32341view13:34, 15 August 2009MaintBotFixed text labels
31957view13:04, 14 August 2009MaintBotFixed group labels
31387view20:44, 13 August 2009MaintBotFixed text labels
31093view01:38, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGDIGGeneProduct394132 (Entrez Gene)
ARHGEF1GeneProduct368266 (Entrez Gene)
CALM1GeneProduct
CFL1GeneProduct406738 (Entrez Gene)
DIAPH1GeneProduct
DKEY-40C11.1GeneProduct564545 (Entrez Gene)
IQGAP2GeneProduct
LOC559119GeneProduct559119 (Entrez Gene) S33596
LOC560360GeneProduct560360 (Entrez Gene)
LOC561737GeneProduct561737 (Entrez Gene)
LOC569144GeneProduct569144 (Entrez Gene)
MYBPHGeneProduct
PAK3GeneProduct
PFN1GeneProduct799355 (Entrez Gene)
PKN1GeneProduct
ROCK1GeneProductS69211
SH3MD2GeneProductPosh
arhgdigGeneProduct394132 (Entrez Gene)
cdc42lGeneProduct793158 (Entrez Gene)
cfl2GeneProduct403001 (Entrez Gene)
gna13aGeneProduct326825 (Entrez Gene)
iqgap1GeneProduct100002928 (Entrez Gene)
limk1GeneProduct735292 (Entrez Gene)
mapk10GeneProduct569698 (Entrez Gene)
p140 Sra-1GeneProduct
pik3cdGeneProduct394174 (Entrez Gene) P42338
pik3r2GeneProduct404211 (Entrez Gene)
ppp1cbGeneProduct100003223 (Entrez Gene)
rac1GeneProduct327204 (Entrez Gene)
rhpn2GeneProduct321330 (Entrez Gene)
rock2aGeneProduct317747 (Entrez Gene) BAA31594
rps6kb1GeneProduct406349 (Entrez Gene) A41687
wasbGeneProduct335158 (Entrez Gene)
waslaGeneProduct100009637 (Entrez Gene)
wu:fb92a07GeneProduct100002263 (Entrez Gene)
wu:fc83c01GeneProduct325488 (Entrez Gene)
zgc:153713GeneProduct751630 (Entrez Gene)
zgc:77231GeneProduct336165 (Entrez Gene)

Annotated Interactions

No annotated interactions
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