ATM signaling (Homo sapiens)

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PCell CycleCheckpointControlAP3B2DNA DamageNBS1InactiveDimerCDC25ARad50Chk2Rad9CellSurvivalFANCD2MDC1Structural change of ChromatinDNARepairBIDBRCA1H2AXMRE11MDMX Ubiquitination &DegradationIR RadiationMDM2PATMATMNBS1Rad50MRE11PATMPSMCATF2P53BP1PPPMDMXPPCDK2CDC25CPCDC2Chk1PTLKPPCheckpointActivationp73Rad51SAPKPPCellSurvivalIkBaPSynaptic VesicleTransportCyclin BTP53c-JunS Phase ofMitotic Cell CyleGADD45AApoptosisATMNF kappa B PathwayCREB1CDK1G2/M transitionApoptosisNegative regulation ofG2/M transitionSenescenceNegative regulationof S phaseDNA repairc-AblDNA repair& Recombinationp211-6S Phase of MitoticCell Cyle


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History

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CompareRevisionActionTimeUserComment
129687view00:47, 22 May 2024EweitzModified title
128135view14:20, 27 January 2024EweitzUse standard order of graphics and labels in legend
128134view14:18, 27 January 2024EweitzUpgrade legend
128133view14:10, 27 January 2024EweitzStandardize case
116808view10:11, 14 May 2021EweitzModified title
115323view09:15, 13 February 2021EgonwMade several pathways clickable
102220view20:49, 11 December 2018Khanspersswitched multiple interactions to segmented
102213view00:14, 11 December 2018Khanspersconverted ineractions to graphical lines in legend
90247view21:13, 26 October 2016AmanzoModification of some titles
90241view17:50, 26 October 2016AmanzoModification on titles of some paths
90240view17:29, 26 October 2016AmanzoPeriodical save, work in progress
84490view23:16, 25 February 2016KhanspersQuick edit to datanode annotation or property
81224view23:13, 5 August 2015AlexanderPicoremoving final IE-incompatible character
81223view22:54, 5 August 2015AlexanderPicoremoving more IE-incompatible character
81218view19:15, 5 August 2015AlexanderPicoremoving IE-incompatible character
79964view14:04, 28 April 2015ZariChanged Id UniProt to Entrez gene for CDC2
78531view10:30, 7 January 2015MaintBotadded missing graphIds
76317view06:53, 2 July 2014MkutmonFixed datasource of S Phase Arrest pathway datanode
72241view18:46, 29 October 2013Khanspersadded one more WP node
72240view18:45, 29 October 2013Khansperschanged pathway node xrefs from GO to WP
71697view19:44, 17 October 2013MaintBotUpdated data sources
70531view16:44, 9 August 2013AmanzoWork in progress
70530view16:42, 9 August 2013AmanzoPeriodical save, work in progress
70529view16:11, 9 August 2013AmanzoPeriodical save, work in progress
70528view16:01, 9 August 2013AmanzoPeriodical save, work in progress
70527view15:50, 9 August 2013AmanzoPeriodical save, work in progress
70458view22:04, 3 August 2013AmanzoPeriodical save, work in progress
70457view21:54, 3 August 2013AmanzoPeriodical save, work in progress
70446view19:05, 1 August 2013AmanzoPeriodical save, work in progress
70445view18:55, 1 August 2013AmanzoPeriodical save, work in progress
70444view18:44, 1 August 2013AmanzoPeriodical save, work in progress
70085view15:44, 12 July 2013AmanzoModified description
70084view15:33, 12 July 2013Amanzowork in progress
70083view15:31, 12 July 2013AmanzoIR figure fixed
70082view15:27, 12 July 2013AmanzoPeriodical save, work in progress
70081view15:13, 12 July 2013AmanzoPeriodical save, work in progress
70072view09:01, 12 July 2013Mkutmonreplaced interaction lines in radiation figure with graphical lines
70004view23:12, 11 July 2013AmanzoModified description
70003view23:11, 11 July 2013AmanzoModified description
70002view23:08, 11 July 2013AmanzoWork in progress
70000view22:57, 11 July 2013AmanzoPeriodical save, work in progress
69999view22:47, 11 July 2013AmanzoPeriodical save, work in progress
69998view22:36, 11 July 2013AmanzoPeriodical save, work in progress
69706view22:54, 9 July 2013AmanzoReferences added
69705view22:49, 9 July 2013AmanzoPeriodical save, work in progress
69704view22:39, 9 July 2013AmanzoPeriodical save, work in progress
69703view22:35, 9 July 2013Amanzowork in progress
69702view22:10, 9 July 2013AmanzoPeriodical save, work in progress
69701view21:59, 9 July 2013AmanzoPeriodical save, work in progress
69698view19:10, 9 July 2013AmanzoPeriodical save, work in progress

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATMGeneProductENSG00000149311 (Ensembl)
ApoptosisPathwayGO:0008630 (GeneOntology)
ApoptosisPathwayGO:0042771 (GeneOntology)
CDK1GeneProductENSG00000170312 (Ensembl)
CREB1GeneProduct1385 (Entrez Gene)
Cyclin BGeneProduct891 (Entrez Gene)
DNA repair & RecombinationPathwayGO:0006281 (GeneOntology)
DNA repairPathwayGO:0006281 (GeneOntology)
G2/M transitionPathwayGO:0000086 (GeneOntology)
GADD45AGeneProduct1647 (Entrez Gene)
NF kappa B PathwayPathwayko04064 (KEGG Pathway)
Negative regulation of S phasePathwayGO:0045749 (GeneOntology)
Negative regulation of G2/M transitionPathwayGO:0010972 (GeneOntology)
S Phase of Mitotic Cell CylePathwayGO:0000084 (GeneOntology)
S Phase of Mitotic Cell CylePathwayGO:0000084 (GeneOntology)
SenescencePathwayGO:0090400 (GeneOntology)
TP53GeneProductENSG00000141510 (Ensembl)
c-AblGeneProductENSG00000097007 (Ensembl)
c-JunGeneProductENSG00000177606 (Ensembl)
p21GeneProductENSG00000124762 (Ensembl)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2516"
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