Ascaroside biosynthesis (Caenorhabditis elegans)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none very long chainfatty acids(VLCFAs)ACOX-1Short chain ascarosidesMAOC-1DHS-28DAF-22beta peroxisomal oxidationName: Ascaroside BiosynthesisLast Modified: 2/20/2013Organism: Caenorhabditis elegans


Description

A proposed role of peroxisomal beta-oxidation enzymes in ascaroside biosynthesis in C. elegans. Ascarosides are small-molecule pheromones that play a role in dauer formation, mating attraction, and social feeding behaviors.

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Quality Tags

Image:MissingXref.pngAnnotate nodes
Image:Curated.pngReview changes for Approved

Ontology Terms

Pathway Ontology : serotonin signaling pathway
Cell Type : neuron
 

Bibliography

  1. von Reuss SH, Bose N, Srinivasan J, Yim JJ, Judkins JC, Sternberg PW, Schroeder FC; ''Comparative metabolomics reveals biogenesis of ascarosides, a modular library of small-molecule signals in C. elegans.''; J Am Chem Soc, 2012 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
135409
Approved
view17:50, 3 September 2024EgonwConverted to use Ensembl identifiers
118113view10:57, 24 May 2021EweitzModified title
84468view19:26, 25 February 2016AlexanderPicoQuick edit to datanode annotation or property
70070view08:46, 12 July 2013Mkutmonfixed unconnected lines
68487view20:53, 5 July 2013MaintBotUpdated to 2013 gpml schema
67063view10:01, 26 June 2013Christine ChichesterOntology Term : 'ascaroside biosynthetic pathway' added !
58837view23:31, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
53148view02:11, 30 October 2012MaintBotModified categories
48971view19:18, 2 July 2012KyookOntology Term : 'lipid metabolic pathway' added !
48970view19:15, 2 July 2012KyookModified description
48942view00:29, 30 June 2012Kyookdraft2
48941view00:27, 30 June 2012KyookPeriodical save, work in progress
48940view00:19, 30 June 2012Kyookdraft
48939view00:17, 30 June 2012KyookNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
ACOX-1GeneProductF08A8.1 (Ensembl)
DAF-22GeneProductY57A10C.6 (WormBase)
DHS-28GeneProductM03A8.1 (WormBase)
MAOC-1GeneProductE04F6.3 (WormBase)
Short chain ascarosidesMetabolite
very long chain

fatty acids

(VLCFAs)		Metabolite

Annotated Interactions

No annotated interactions

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