IL-5 signaling pathway (Gallus gallus)

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DPlasma membraneDDD(Protein-protein interaction)EndosomePMControlDDEndoplasmic reticulumUbiquitinationGolgi apparatusAutophosphorylationAccession Number: NetPath 17MitochondriaDRecruitmentPalmitoylationExtracellularMolecular associationCY->PMDNucleusGlycosylationDDCYCY->NUReceptorDeacetylationNUDEnzyme complexPM->NUPM->NUCY->MTERPM->NUAcetylationDesumoylationCY->NUTranslocationSumoylationProteolytic cleavageActivationENDPhosphorylationMethylationDephosphorylationDReaction through unknown mechanisms/moleculesDemethylationDeubiquitinationCY->NUDGODMTDLigandCytoplasmInhibitionDDMolecule in the pathwayProteins in a complex interactionECGene SymbolFOXO3PRKCDMAPK1ITGB2NFKB1STAT5BMAP2K2GSK3BNFKB1PIK3R2ITGAMPTPN11RCJMB04_19o18RAPGEF1JAK1IL5CBLCDKN1BSOX4STAT5BPRKCDMAPK9GSK3AJUNSTAT5AIL5RCJMB04_11l21MAPK14SH2B2HRASRCJMB04_17i9NFKBIARAP1GAPCRKLGRB2PRKCBICAM3ATF2ALOX5APSOCS1PTPN6BAXCSF2RBLYNSTAT3ALOX5CSF2RBHCKCSF2RBIL5RAJAK2IL5RAPIK3R1CRKLIL2RBBAXCTNNB1UNC119ALOX5RAF1PLA2G4AAKT1SHC1RPS6KA1DNM2KRASHCLS1ICAM1BTKCCND3VAV1SHC2PIK3CGSTAT5AMAPK3RCJMB04_35e13ELK1CTNNB1PIM1RAC1PTK2B


Description

No description

Comments

GenMAPP notes 
NetPath 17 - IL-5 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP127(r20949) with a 66% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
118002view11:30, 23 May 2021EweitzModified title
86935view13:06, 15 July 2016MkutmonOntology Term : 'interleukin-5 signaling pathway' added !
68860view17:20, 8 July 2013MaintBotUpdated to 2013 gpml schema
40998view22:56, 1 March 2011MaintBotRemoved redundant pathway information and comments
33919view18:06, 9 December 2009MaintBotAutomatic update of empty xrefs
31488view21:28, 13 August 2009MaintBotFixed text labels
30313view20:40, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct395928 (Entrez Gene)
ALOX5GeneProduct423769 (Entrez Gene)
ALOX5APGeneProduct770904 (Entrez Gene)
ATF2GeneProduct395727 (Entrez Gene)
BAXGeneProduct
BTKGeneProduct374075 (Entrez Gene)
CBLGeneProduct374038 (Entrez Gene)
CCND3GeneProduct419928 (Entrez Gene)
CDKN1BGeneProduct769872 (Entrez Gene)
CRKLGeneProduct416939 (Entrez Gene)
CSF2RBGeneProduct771315 (Entrez Gene)
CTNNB1GeneProduct395964 (Entrez Gene)
DNM2GeneProduct
ELK1GeneProduct
FOXO3GeneProduct421769 (Entrez Gene)
GRB2GeneProduct386572 (Entrez Gene)
GSK3AGeneProduct
GSK3BGeneProduct418335 (Entrez Gene)
HCKGeneProduct419280 (Entrez Gene)
HCLS1GeneProduct426867 (Entrez Gene)
HRASGeneProduct396229 (Entrez Gene)
ICAM1GeneProduct
ICAM3GeneProduct
IL2RBGeneProduct
IL5GeneProduct474360 (Entrez Gene)
IL5RAGeneProduct771801 (Entrez Gene)
ITGAMGeneProduct
ITGB2GeneProduct396181 (Entrez Gene)
JAK1GeneProduct395681 (Entrez Gene)
JAK2GeneProduct374199 (Entrez Gene)
JUNGeneProduct424673 (Entrez Gene)
KRASGeneProduct418207 (Entrez Gene)
LYNGeneProduct421127 (Entrez Gene)
MAP2K2GeneProduct396349 (Entrez Gene)
MAPK1GeneProduct373953 (Entrez Gene)
MAPK14GeneProduct421183 (Entrez Gene)
MAPK3GeneProduct
MAPK9GeneProduct395983 (Entrez Gene)
NFKB1GeneProduct396033 (Entrez Gene)
NFKBIAGeneProduct396093 (Entrez Gene)
PIK3CGGeneProduct417706 (Entrez Gene)
PIK3R1GeneProduct427171 (Entrez Gene)
PIK3R2GeneProduct771142 (Entrez Gene)
PIM1GeneProduct
PLA2G4AGeneProduct396394 (Entrez Gene)
PRKCBGeneProduct416567 (Entrez Gene)
PRKCDGeneProduct415905 (Entrez Gene)
PTK2BGeneProduct421998 (Entrez Gene)
PTPN11GeneProduct395815 (Entrez Gene)
PTPN6GeneProduct427947 (Entrez Gene)
RAC1GeneProduct395871 (Entrez Gene)
RAF1GeneProduct396245 (Entrez Gene)
RAP1GAPGeneProduct395647 (Entrez Gene)
RAPGEF1GeneProduct417173 (Entrez Gene)
RCJMB04_11l21GeneProduct425619 (Entrez Gene)
RCJMB04_17i9GeneProduct424044 (Entrez Gene)
RCJMB04_19o18GeneProduct427272 (Entrez Gene)
RCJMB04_35e13GeneProduct421136 (Entrez Gene)
RPS6KA1GeneProduct386579 (Entrez Gene)
SH2B2GeneProduct771172 (Entrez Gene)
SHC1GeneProduct395934 (Entrez Gene)
SHC2GeneProduct770341 (Entrez Gene)
SOCS1GeneProduct416630 (Entrez Gene)
SOX4GeneProduct395143 (Entrez Gene)
STAT3GeneProduct420027 (Entrez Gene)
STAT5AGeneProduct
STAT5BGeneProduct395556 (Entrez Gene)
UNC119GeneProduct771690 (Entrez Gene)
VAV1GeneProduct

Annotated Interactions

No annotated interactions
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