T cell receptor signaling pathway (Mus musculus)

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Reaction through unknown mechanisms/moleculesLigandDDemethylationNUMethylationMolecular associationPMAutophosphorylationNU->CYAcetylationAccession Number: NetPath_11Endoplasmic reticulumGOPalmitoylationUbiquitinationGlycosylationDeubiquitinationMolecule in the pathwayActivationDephosphorylationRecruitmentProteolytic cleavageSumoylationNucleusExtracellularCytoplasmEndosomeECGene SymbolControlInhibitionCY->NUERDesumoylationENPhosphorylationDGolgi apparatusProteins in a complex interactionCY->PMTranslocationAntigenMT(Protein-protein interaction)Plasma membraneMitochondrionCY->NUDeacetylationEnzyme complexReceptorCYStk39Rac2Lax1Cd3eMap4k1Stat5aJunGm2423Def6CblbGab2PtprhArhgef7Wipf1Mapk1Pag1Cd247BrafShbPpp3cbItpr1Ripk2Muc1LatPtpn6Abl1CDC42Ptk2CebpbDusp3Zap70Git2Creb1Dtx1DbnlSlaSh3bp2Mapk7GrapPtk2bItkShc1Dnm2Ptpn12Nfam1Tuba4aLynCd2Map3k1LckStat5bRasgrp2Sh2d2aCblTubb5Rapgef1PxnCd2apPTPN3Skap1Cd8aSkap2VaspFosCd3dCrebbpDock2ENAHHomer3Ctnnb1FynPrkd2Rasa1SykPlcg1Vav2Fcrl5Nfatc2TRB@Nedd9Cd4Vav3Sh2d3cTxkPik3r1Unc119JunAkt1Jak3EvlRap1aGrb2Map2k2Ptpn11Stat1Pstpip1Card11Pak1CrkHdac7ArhgdibKhdrbs1Hdac7Cd3gSos1Acp1Mapk3Lcp2Cd3ePrkcqPik3r2Trat1Lime1TRA@Cd5FybCd247CrklWasf2PtprjAbi1Map2k1Stat5aSos2Vav1Grap2Lcp2Sla2Lime1PtprcNCLDlg1Sh2b3Stat5bNck1FybNck1Sit1Bcl10Cabin1SrcCishPtpn22Arhgef6Was


Description

No description

Comments

GenMAPP notes 
NetPath_11 - T Cell Receptor Signaling Pathway NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP69(r20823) with a 95% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
118027view11:43, 23 May 2021EweitzModified title
111023view14:40, 30 June 2020L DupuisConverted interaction lines in legend to grpahical lines
69149view18:17, 8 July 2013MaintBotUpdated to 2013 gpml schema
67682view11:48, 26 June 2013DdiglesOntology Term : 'T cell receptor signaling pathway' added !
41339view00:26, 2 March 2011MaintBotRemoved redundant pathway information and comments
34406view23:05, 9 December 2009MaintBotAutomatic update of empty xrefs
31461view21:15, 13 August 2009MaintBotFixed text labels
30852view00:07, 30 July 2009MaintBotConverted from Homo sapiens
21690view11:32, 14 November 2008MaintBot[[Pathway:Mus musculus:T-Cell-Receptor NetPath 11]] moved to [[Pathway:WP480]]: Moved to stable identifier
8428view13:46, 7 January 2008MaintBot[[Pathway:Mouse:T-Cell-Receptor NetPath 11]] moved to [[Pathway:Mus musculus:T-Cell-Receptor NetPath 11]]: Renaming species
7831view16:20, 18 December 2007MaintBotfixed category names
7299view12:42, 4 November 2007MaintBotAdded categories to GPML
6500view22:19, 22 May 2007A.Pandeygpml file for [[Mouse:T-Cell-Receptor_NetPath_11]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Abi1GeneProduct11308 (Entrez Gene)
Abl1GeneProduct11350 (Entrez Gene)
Acp1GeneProduct11431 (Entrez Gene)
Akt1GeneProduct11651 (Entrez Gene)
ArhgdibGeneProduct11857 (Entrez Gene)
Arhgef6GeneProduct73341 (Entrez Gene)
Arhgef7GeneProduct54126 (Entrez Gene)
Bcl10GeneProduct12042 (Entrez Gene)
BrafGeneProduct109880 (Entrez Gene)
CDC42GeneProduct12540 (Entrez Gene)
Cabin1GeneProduct104248 (Entrez Gene)
Card11GeneProduct108723 (Entrez Gene)
CblGeneProduct12402 (Entrez Gene)
CblbGeneProduct208650 (Entrez Gene)
Cd2GeneProduct12481 (Entrez Gene)
Cd247GeneProduct12503 (Entrez Gene)
Cd2apGeneProduct12488 (Entrez Gene)
Cd3dGeneProduct12500 (Entrez Gene)
Cd3eGeneProduct12501 (Entrez Gene)
Cd3gGeneProduct12502 (Entrez Gene)
Cd4GeneProduct12504 (Entrez Gene)
Cd5GeneProduct12507 (Entrez Gene)
Cd8aGeneProduct12525 (Entrez Gene)
CebpbGeneProduct12608 (Entrez Gene)
CishGeneProduct12700 (Entrez Gene)
Creb1GeneProduct12912 (Entrez Gene)
CrebbpGeneProduct12914 (Entrez Gene)
CrkGeneProduct12928 (Entrez Gene)
CrklGeneProduct12929 (Entrez Gene)
Ctnnb1GeneProduct12387 (Entrez Gene)
DbnlGeneProduct13169 (Entrez Gene)
Def6GeneProduct23853 (Entrez Gene)
Dlg1GeneProduct13383 (Entrez Gene)
Dnm2GeneProduct13430 (Entrez Gene)
Dock2GeneProduct94176 (Entrez Gene)
Dtx1GeneProduct14357 (Entrez Gene)
Dusp3GeneProduct72349 (Entrez Gene)
ENAHGeneProduct13800 (Entrez Gene)
EvlGeneProduct14026 (Entrez Gene)
Fcrl5GeneProduct329693 (Entrez Gene)
FosGeneProduct14281 (Entrez Gene)
FybGeneProduct23880 (Entrez Gene)
FynGeneProduct14360 (Entrez Gene)
Gab2GeneProduct14389 (Entrez Gene)
Git2GeneProduct26431 (Entrez Gene)
Gm2423GeneProduct100039786 (Entrez Gene)
Grap2GeneProduct17444 (Entrez Gene)
GrapGeneProduct71520 (Entrez Gene)
Grb2GeneProduct14784 (Entrez Gene)
Hdac7GeneProduct56233 (Entrez Gene)
Homer3GeneProduct26558 (Entrez Gene)
ItkGeneProduct16428 (Entrez Gene)
Itpr1GeneProduct16438 (Entrez Gene)
Jak3GeneProduct16453 (Entrez Gene)
JunGeneProduct16476 (Entrez Gene)
Khdrbs1GeneProduct20218 (Entrez Gene)
LatGeneProduct16797 (Entrez Gene)
Lax1GeneProduct240754 (Entrez Gene)
LckGeneProduct16818 (Entrez Gene)
Lcp2GeneProduct16822 (Entrez Gene)
Lime1GeneProduct72699 (Entrez Gene)
LynGeneProduct17096 (Entrez Gene)
Map2k1GeneProduct26395 (Entrez Gene)
Map2k2GeneProduct26396 (Entrez Gene)
Map3k1GeneProduct26401 (Entrez Gene)
Map4k1GeneProduct26411 (Entrez Gene)
Mapk1GeneProduct26413 (Entrez Gene)
Mapk3GeneProduct26417 (Entrez Gene)
Mapk7GeneProduct23939 (Entrez Gene)
Muc1GeneProduct17829 (Entrez Gene)
NCLGeneProduct17975 (Entrez Gene)
Nck1GeneProduct17973 (Entrez Gene)
Nedd9GeneProduct18003 (Entrez Gene)
Nfam1GeneProduct74039 (Entrez Gene)
Nfatc2GeneProduct18019 (Entrez Gene)
PTPN3GeneProduct545622 (Entrez Gene)
Pag1GeneProduct94212 (Entrez Gene)
Pak1GeneProduct18479 (Entrez Gene)
Pik3r1GeneProduct18708 (Entrez Gene)
Pik3r2GeneProduct18709 (Entrez Gene)
Plcg1GeneProduct18803 (Entrez Gene)
Ppp3cbGeneProduct19056 (Entrez Gene)
PrkcqGeneProduct18761 (Entrez Gene)
Prkd2GeneProduct101540 (Entrez Gene)
Pstpip1GeneProduct19200 (Entrez Gene)
Ptk2GeneProduct14083 (Entrez Gene)
Ptk2bGeneProduct19229 (Entrez Gene)
Ptpn11GeneProduct19247 (Entrez Gene)
Ptpn12GeneProduct19248 (Entrez Gene)
Ptpn22GeneProduct19260 (Entrez Gene)
Ptpn6GeneProduct15170 (Entrez Gene)
PtprcGeneProduct19264 (Entrez Gene)
PtprhGeneProduct545902 (Entrez Gene)
PtprjGeneProduct19271 (Entrez Gene)
PxnGeneProduct19303 (Entrez Gene)
Rac2GeneProduct19354 (Entrez Gene)
Rap1aGeneProduct109905 (Entrez Gene)
Rapgef1GeneProduct107746 (Entrez Gene)
Rasa1GeneProduct218397 (Entrez Gene)
Rasgrp2GeneProduct19395 (Entrez Gene)
Ripk2GeneProduct192656 (Entrez Gene)
Sh2b3GeneProduct16923 (Entrez Gene)
Sh2d2aGeneProduct27371 (Entrez Gene)
Sh2d3cGeneProduct27387 (Entrez Gene)
Sh3bp2GeneProduct24055 (Entrez Gene)
ShbGeneProduct230126 (Entrez Gene)
Shc1GeneProduct20416 (Entrez Gene)
Sit1GeneProduct54390 (Entrez Gene)
Skap1GeneProduct78473 (Entrez Gene)
Skap2GeneProduct54353 (Entrez Gene)
SlaGeneProduct20491 (Entrez Gene)
Sla2GeneProduct77799 (Entrez Gene)
Sos1GeneProduct20662 (Entrez Gene)
Sos2GeneProduct20663 (Entrez Gene)
SrcGeneProduct20779 (Entrez Gene)
Stat1GeneProduct20846 (Entrez Gene)
Stat5aGeneProduct20850 (Entrez Gene)
Stat5bGeneProduct20851 (Entrez Gene)
Stk39GeneProduct53416 (Entrez Gene)
SykGeneProduct20963 (Entrez Gene)
TRA@GeneProduct
TRB@GeneProduct
Trat1GeneProduct77647 (Entrez Gene)
Tuba4aGeneProduct22145 (Entrez Gene)
Tubb5GeneProduct22154 (Entrez Gene)
TxkGeneProduct22165 (Entrez Gene)
Unc119GeneProduct22248 (Entrez Gene)
VaspGeneProduct22323 (Entrez Gene)
Vav1GeneProduct22324 (Entrez Gene)
Vav2GeneProduct22325 (Entrez Gene)
Vav3GeneProduct57257 (Entrez Gene)
WasGeneProduct22376 (Entrez Gene)
Wasf2GeneProduct242687 (Entrez Gene)
Wipf1GeneProduct215280 (Entrez Gene)
Zap70GeneProduct22637 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP480"
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