T cell receptor signaling pathway (Pan troglodytes)

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MTRecruitmentActivationERCY->PMD(Protein-protein interaction)Accession Number: NetPath_11AutophosphorylationDeubiquitinationMethylationPalmitoylationNucleusAcetylationReceptorCY->NUDephosphorylationGlycosylationDemethylationReaction through unknown mechanisms/moleculesECEndosomeTranslocationENGene SymbolLigandDeacetylationControlEndoplasmic reticulumCY->NUMolecular associationAntigenSumoylationNUProteins in a complex interactionPMProteolytic cleavageMitochondrionMolecule in the pathwayExtracellularUbiquitinationDCYEnzyme complexGODesumoylationCytoplasmPhosphorylationGolgi apparatusNU->CYInhibitionPlasma membraneNEDD9MAPK7PLCG1SH3BP2SYKITKSLA2JAK3SHBWASF2SHC1UNC119RASA1STAT5BDUSP3RAPGEF1VAV1CARD11PTPRJCD5PXNFYBMAP3K1LCKDOCK2NFAM1TRB@PTK2BSKAP2GRB2JUNNFATC2VASPZAP70MAP2K2GRAP2STAT5BDLG1PTPN3CEBPBSH2D3CPPP3CBDBNLTUBA4AHOMER3DTX1ARHGDIBCBLBTRA@SOS1LIME1STK39VAV3PIK3R2ARHGEF7EVLSH2D2ALOC466968SOS2CD247GRAPTRAT1CD247JUNPRKD2PTPN12ITPR1SLAFOSBRAFFCRL3LATPTPN22MAP4K1MAPK3PTPRCFYBCD4TXKCD3DMAP2K1ENAHWASAKT1RAP1AABI1VAV2CD2APPTPN6CD3GDEF6CD2CISHCRKLCP2PRKCQSRCCTNNB1CD8ACDC42NCLRAC2GIT2ARHGEF6PAG1MAPK1NCK1PTK2CREBBPSIT1BCL10STAT1CD3ESTAT5ANCK1PTPN11SKAP1PSTPIP1TUBBLOC466968STAT5AABL1FYNPAK1CREB1LIME1KHDRBS1SH2B3RASGRP2CABIN1PIK3R1GAB2LCP2ACP1CBLRIPK2PTPRHCRKLLYNCD3EWIPF1MUC1YWHAQDNM2LAX1


Description

No description

Comments

GenMAPP notes 
NetPath_11 - T Cell Receptor Signaling Pathway NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP69(r20823) with a 82% conversion rate.

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Bibliography

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History

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CompareRevisionActionTimeUserComment
118023view11:41, 23 May 2021EweitzModified title
87703view09:01, 25 July 2016MirellaKalafatiOntology Term : 'T cell' added !
87702view09:01, 25 July 2016MirellaKalafatiOntology Term : 'signaling pathway' added !
69260view18:37, 8 July 2013MaintBotUpdated to 2013 gpml schema
41567view01:59, 2 March 2011MaintBotRemoved redundant pathway information and comments
34295view22:03, 9 December 2009MaintBotAutomatic update of empty xrefs
31584view22:03, 13 August 2009MaintBotFixed text labels
30463view21:29, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI1GeneProduct450363 (Entrez Gene)
ABL1GeneProduct464802 (Entrez Gene)
ACP1GeneProduct458990 (Entrez Gene)
AKT1GeneProduct740898 (Entrez Gene)
ARHGDIBGeneProduct742002 (Entrez Gene)
ARHGEF6GeneProduct473803 (Entrez Gene)
ARHGEF7GeneProduct452673 (Entrez Gene)
BCL10GeneProduct456984 (Entrez Gene)
BRAFGeneProduct463781 (Entrez Gene)
CABIN1GeneProduct458709 (Entrez Gene)
CARD11GeneProduct463235 (Entrez Gene)
CBLGeneProduct451690 (Entrez Gene)
CBLBGeneProduct460566 (Entrez Gene)
CD2GeneProduct449512 (Entrez Gene)
CD247GeneProduct748272 (Entrez Gene)
CD2APGeneProduct472241 (Entrez Gene)
CD3DGeneProduct451584 (Entrez Gene)
CD3EGeneProduct742330 (Entrez Gene)
CD3GGeneProduct451585 (Entrez Gene)
CD4GeneProduct450124 (Entrez Gene)
CD5GeneProduct737721 (Entrez Gene)
CD8AGeneProduct735755 (Entrez Gene)
CDC42GeneProduct456609 (Entrez Gene)
CEBPBGeneProduct469969 (Entrez Gene)
CISHGeneProduct470819 (Entrez Gene)
CREB1GeneProduct459901 (Entrez Gene)
CREBBPGeneProduct467891 (Entrez Gene)
CRKGeneProduct747142 (Entrez Gene)
CRKLGeneProduct470146 (Entrez Gene)
CTNNB1GeneProduct450183 (Entrez Gene)
DBNLGeneProduct463925 (Entrez Gene)
DEF6GeneProduct462636 (Entrez Gene)
DLG1GeneProduct460968 (Entrez Gene)
DNM2GeneProduct455718 (Entrez Gene)
DOCK2GeneProduct471731 (Entrez Gene)
DTX1GeneProduct739385 (Entrez Gene)
DUSP3GeneProduct468271 (Entrez Gene)
ENAHGeneProduct
EVLGeneProduct746207 (Entrez Gene)
FCRL3GeneProduct469519 (Entrez Gene)
FOSGeneProduct453047 (Entrez Gene)
FYBGeneProduct
FYNGeneProduct462944 (Entrez Gene)
GAB2GeneProduct748918 (Entrez Gene)
GIT2GeneProduct452227 (Entrez Gene)
GRAP2GeneProduct744653 (Entrez Gene)
GRAPGeneProduct454496 (Entrez Gene)
GRB2GeneProduct737245 (Entrez Gene)
HOMER3GeneProduct736171 (Entrez Gene)
ITKGeneProduct735556 (Entrez Gene)
ITPR1GeneProduct460134 (Entrez Gene)
JAK3GeneProduct455848 (Entrez Gene)
JUNGeneProduct456893 (Entrez Gene)
KHDRBS1GeneProduct456705 (Entrez Gene)
LATGeneProduct743295 (Entrez Gene)
LAX1GeneProduct741370 (Entrez Gene)
LCKGeneProduct
LCP2GeneProduct471734 (Entrez Gene)
LIME1GeneProduct
LOC466968GeneProduct466968 (Entrez Gene)
LYNGeneProduct472771 (Entrez Gene)
MAP2K1GeneProduct450188 (Entrez Gene)
MAP2K2GeneProduct456390 (Entrez Gene)
MAP3K1GeneProduct471543 (Entrez Gene)
MAP4K1GeneProduct748652 (Entrez Gene)
MAPK1GeneProduct458680 (Entrez Gene)
MAPK3GeneProduct454037 (Entrez Gene)
MAPK7GeneProduct454499 (Entrez Gene)
MUC1GeneProduct
NCK1GeneProduct460720 (Entrez Gene)
NCLGeneProduct460006 (Entrez Gene)
NEDD9GeneProduct462433 (Entrez Gene)
NFAM1GeneProduct746287 (Entrez Gene)
NFATC2GeneProduct469972 (Entrez Gene)
PAG1GeneProduct464253 (Entrez Gene)
PAK1GeneProduct451439 (Entrez Gene)
PIK3R1GeneProduct461836 (Entrez Gene)
PIK3R2GeneProduct455855 (Entrez Gene)
PLCG1GeneProduct458253 (Entrez Gene)
PPP3CBGeneProduct450898 (Entrez Gene)
PRKCQGeneProduct450288 (Entrez Gene)
PRKD2GeneProduct468929 (Entrez Gene)
PSTPIP1GeneProduct
PTK2GeneProduct464422 (Entrez Gene)
PTK2BGeneProduct464073 (Entrez Gene)
PTPN11GeneProduct748225 (Entrez Gene)
PTPN12GeneProduct463494 (Entrez Gene)
PTPN22GeneProduct457136 (Entrez Gene)
PTPN3GeneProduct464648 (Entrez Gene)
PTPN6GeneProduct748032 (Entrez Gene)
PTPRCGeneProduct457607 (Entrez Gene)
PTPRHGeneProduct469013 (Entrez Gene)
PTPRJGeneProduct451181 (Entrez Gene)
PXNGeneProduct452303 (Entrez Gene)
RAC2GeneProduct742575 (Entrez Gene)
RAP1AGeneProduct469408 (Entrez Gene)
RAPGEF1GeneProduct464812 (Entrez Gene)
RASA1GeneProduct461762 (Entrez Gene)
RASGRP2GeneProduct451298 (Entrez Gene)
RIPK2GeneProduct464277 (Entrez Gene)
SH2B3GeneProduct452245 (Entrez Gene)
SH2D2AGeneProduct457406 (Entrez Gene)
SH2D3CGeneProduct464753 (Entrez Gene)
SH3BP2GeneProduct461080 (Entrez Gene)
SHBGeneProduct465107 (Entrez Gene)
SHC1GeneProduct457351 (Entrez Gene)
SIT1GeneProduct746721 (Entrez Gene)
SKAP1GeneProduct468432 (Entrez Gene)
SKAP2GeneProduct463306 (Entrez Gene)
SLA2GeneProduct735438 (Entrez Gene)
SLAGeneProduct464409 (Entrez Gene)
SOS1GeneProduct459171 (Entrez Gene)
SOS2GeneProduct452897 (Entrez Gene)
SRCGeneProduct458229 (Entrez Gene)
STAT1GeneProduct459834 (Entrez Gene)
STAT5AGeneProduct454681 (Entrez Gene)
STAT5BGeneProduct454679 (Entrez Gene)
STK39GeneProduct459711 (Entrez Gene)
SYKGeneProduct464586 (Entrez Gene)
TRA@GeneProduct
TRAT1GeneProduct741922 (Entrez Gene)
TRB@GeneProduct742350 (Entrez Gene)
TUBA4AGeneProduct470654 (Entrez Gene)
TUBBGeneProduct471960 (Entrez Gene)
TXKGeneProduct461344 (Entrez Gene)
UNC119GeneProduct455028 (Entrez Gene)
VASPGeneProduct468919 (Entrez Gene)
VAV1GeneProduct455647 (Entrez Gene)
VAV2GeneProduct
VAV3GeneProduct457076 (Entrez Gene)
WASGeneProduct
WASF2GeneProduct456675 (Entrez Gene)
WIPF1GeneProduct459755 (Entrez Gene)
YWHAQGeneProduct470302 (Entrez Gene)
ZAP70GeneProduct459427 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP894"
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