Translation factors (Saccharomyces cerevisiae)
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mRNA
Pre-initiation Complex
Translocation
Initiation
60S Subunit
Elongation
AUG
43S Pre-initiation Complex
Recruitment of 60S subunit
and first peptide bond
m7G
Guanine Nucleotide Exchange
Termination
Cap Binding Complex
scanning
AAAAAAAAAAAAAAA
40S Subunit
Binds aminoacyl-tRNA
Recruitment of 43S
eIF4H??
IF2
eIF4E
PAB1??
eEF1 gamma 2
eIF2B beta
eIF3 p33
eIF4F p20
4E-BP2??
eIF4F p130
eIF3 p90
eIF2 alpha Kinase 1??
eIF2B gamma
eIF1
eEF1 alpha
eRF3b???
eIF3 p135
4E-BP3??
IF2M
eIF1A
eIF2 alpha Kinase 2??
eIF2B delta
eEF1 gamma 1
eIF5A-II
eIF3 p110
eIF2 beta
eIF2B epsilon
eIF2 alpha
eIF5A-I
eIF3 p62
eIF5
eIF4G-I??
eRF1
eIF2 gamma
eIF6
eIF2 alpha Kinase 3??
eIF4G-II??
eIF-3 p30
Sui1 Homolog A121??
eIF4A
eIF2B alpha
eIF4B
eIF3 p39
4E-BP1??
eEF1 beta
eIF4F p150
PAIP-1
eIF3 p93
eEF2
eEF2 Kinase??
eRF2
Description
No description
Comments
GenMAPP remarks
Based on
http://pathway.yeastgenome.org/biocyc/
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Bibliography
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History
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Compare
Revision
Action
Time
User
Comment
127993
view
23:52, 20 January 2024
Eweitz
Group nodes, fix interactions, standardize case
127992
view
23:47, 20 January 2024
Eweitz
Fix some interactions, use one object for multiline labels, standardize case
117350
view
11:54, 20 May 2021
Eweitz
Modified title
71347
view
18:02, 17 October 2013
MaintBot
Automated update of data sources
69628
view
20:35, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67712
view
11:53, 26 June 2013
Ddigles
Ontology Term : 'translation pathway' added !
62697
view
23:07, 1 May 2013
MaintBot
Updated UniProt data source
41863
view
04:51, 2 March 2011
MaintBot
Removed redundant pathway information and comments
20745
view
11:29, 14 November 2008
MaintBot
[[Pathway:Saccharomyces cerevisiae:Translation Factors]] moved to [[Pathway:WP32]]: Moved to stable identifier
8966
view
14:13, 7 January 2008
MaintBot
Added to category $category
8964
view
14:13, 7 January 2008
M.Braymer
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
4E-BP1??
GeneProduct
Q13541 (Uniprot/TrEMBL)
4E-BP2??
GeneProduct
Q13542 (Uniprot/TrEMBL)
4E-BP3??
GeneProduct
O60516 (Uniprot/TrEMBL)
IF2M
GeneProduct
S000005383 (SGD)
IF-2, mitochondrial [Precursor]
IF2
GeneProduct
S000000033 (SGD)
PAB1??
GeneProduct
P11940 (Uniprot/TrEMBL)
PAIP-1
GeneProduct
S000000834 (SGD)
Sui1 Homolog A121??
GeneProduct
Q9UNQ9 (Uniprot/TrEMBL)
eEF1 alpha
GeneProduct
S000000322 (SGD)
eEF1 beta
GeneProduct
S000000003 (SGD)
eEF1 gamma 1
GeneProduct
S000005969 (SGD)
eEF1 gamma 2
GeneProduct
S000001564 (SGD)
eEF2 Kinase??
GeneProduct
O00418 (Uniprot/TrEMBL)
eEF2
GeneProduct
S000002793 (SGD)
eIF-3 p30
GeneProduct
S000004182 (SGD)
Possible eukaryotic translation initiation factor 3 30 kDa subunit
eIF1A
GeneProduct
S000004873 (SGD)
eIF1
GeneProduct
S000005188 (SGD)
eIF2 alpha Kinase 1??
GeneProduct
Q9BQI3 (Uniprot/TrEMBL)
eIF2 alpha Kinase 2??
GeneProduct
P19525 (Uniprot/TrEMBL)
now E2K2_HUMAN
eIF2 alpha Kinase 3??
GeneProduct
Q9NZJ5 (Uniprot/TrEMBL)
eIF2 alpha
GeneProduct
S000003767 (SGD)
eIF2 beta
GeneProduct
S000006158 (SGD)
eIF2 gamma
GeneProduct
S000000827 (SGD)
eIF2B alpha
GeneProduct
S000001734 (SGD)
eIF2B beta
GeneProduct
S000004282 (SGD)
eIF2B delta
GeneProduct
S000003315 (SGD)
eIF2B epsilon
GeneProduct
S000002619 (SGD)
eIF2B gamma
GeneProduct
S000005786 (SGD)
eIF3 p110
GeneProduct
S000000283 (SGD)
eIF3 p135
GeneProduct
S000004614 (SGD)
eIF3 p33
GeneProduct
S000002837 (SGD)
eIF3 p39
GeneProduct
S000004754 (SGD)
eIF3 p62
GeneProduct
S000005006 (SGD)
eIF3 p90
GeneProduct
S000005888 (SGD)
eIF3 p93
GeneProduct
S000004926 (SGD)
eIF4A
GeneProduct
S000001767 (SGD)
eIF4B
GeneProduct
S000006367 (SGD)
eIF4E
GeneProduct
S000005499 (SGD)
eIF4F p130
GeneProduct
S000003017 (SGD)
eIF4F p150
GeneProduct
S000003394 (SGD)
eIF4F p20
GeneProduct
S000005802 (SGD)
eIF4G-I??
GeneProduct
Q04637 (Uniprot/TrEMBL)
TrEMBL accession number O43177 refers to same protein.
eIF4G-II??
GeneProduct
O43432 (Uniprot/TrEMBL)
eIF4H??
GeneProduct
Q15056 (Uniprot/TrEMBL)
eIF5A-II
GeneProduct
S000000760 (SGD)
eIF5A-I
GeneProduct
S000003808 (SGD)
eIF5
GeneProduct
S000006245 (SGD)
eIF6
GeneProduct
S000006220 (SGD)
eRF1
GeneProduct
S000000347 (SGD)
eRF2
GeneProduct
S000002579 (SGD)
eRF3b???
GeneProduct
Q9NY44 (Uniprot/TrEMBL)
Annotated Interactions
No annotated interactions
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