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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Wnt signaling Canonical Non-canonical RTK-Ras Core components TGFbeta signaling Notch signaling ligands receptors Binding components Nuclear complex MAPK p38 Jun Erk Ligands Type I receptors Type II receptors R-smad Co-smad I-smad Transcription factors Insulin-like signaling TOR signaling TOR complex 2 TOR complex 1 Major targets Receptor Second messenger system Transcription factor mom-1 mom-2 lin-44 egl-20 cwn-1 cwn-2 Y73B6BL.21 mom-5 lin-17 mig-1 cfz-2 lrp-1 mig-5 dsh-1 dsh-2 kin-19 pry-1 apr-1 lin-23 wrm-1 bar-1 hmp-2 pop-1 unc-37 lit-1 mom-4 tap-1 par-1 daf-1 daf-7 daf-3 daf-5 unc-43 tir-1 sek-1 pmk-1 skn-1 gcs-1 egl-15 egl-17 ksr-1 ksr-2 let-23 let-60 let-756 lin-3 lin-45 mek-2 mpk-1 sem-5 sos-1 jnk-1 jkk-1 mek-1 nsy-1 mkk-4 pmk-2 pmk-3 mpk-2 daf-14 daf-8 tig-2 unc-129 dbl-1 sma-2 sma-3 sma-4 sma-6 tag-68 daf-12 sma-9 lin-31 tig-3 lin-12 glp-1 lag-2 apx-1 dsl-1 sup-17 adm-4 sel-12 hop-1 aph-1 aph-2 pen-2 lag-1 sel-8 dlk-1 daf-4 daf-2 let-363 daf-16 age-1 akt-1 daf-18 akt-2 sgk-1 daf-15 C10H11.8 sinh-1 let-363 C10H11.8 rict-1 rheb-1 rsks-1 hif-1 rps-6 unc-51 pdk-1 Name: Metapathway Signal Transduction License: CC BY 2.0 Last Modified: 2/20/2013 Organism: Caenorhabditis elegans
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Review changes for Approved Revision 135384 of this pathway was approved for data analysis by Egon Willighagen .
Annotated lists Annotated lists of gene products are considered useful for analysis and for stimulating future pathway curation.
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