Regulation of actin cytoskeleton (Danio rerio)

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Stabilizationof actinRTKRASActomyosinassembly contractionGPCRRTKGene ExpressionGPCRRASGrowth Factor (GF)GFActin polymerizationChemotatic factor+pPI3KActin polymerizationstress fiberLamellipodiaFilipodiaFocal complexassemblyPI3K?Chemotactic factorActin polymerization-pFocal adhesionassemblystress fibersi:dkey-74f15.3LPSFGF2msnbARPC5mapk3Apc2f2fgf14zgc:153713fgfr4mylkbARHGEF1SOS1limk1myl1TMSB4XFGF20CFL1arhgef7aLOC442775LOC100149843cskfn1WASF1pik3cbPFN1LOC792708wasbLOC558288Adherens junctionpathwayegfrassh1bmsnaLOC100536317mosFGF6iqgap1pip4k2aacrkvclpik3cgcfl2si:ch211-197g15.13cdc42lptk2.1vil1lfgf8abrafdock1PIK3C2Gegfitga1chrm2anckap1rac2slc9a1pak7PAK3gna12DIAP3myh10fgd1ROCK1FGF9DIAP1zgc:153663f2rPIP2actn1ENAHrrasMAP2K2sos2fgf5Focal AdhesionpathwayACTG1rras2Focal Adhesionpathwaypik3r2PIP2GNG12pdgfraFGF21pip5k1abFGF22wu:fc03h05mapk6LOC565130INS1PDGFALOC100330960nraspik3r3zgc:92014LOC557176gsnachrm5aVAV1rac1gna13apip5k1bbzgc:114164chrm3aBAIAP2cyfip2si:dkey-24l11.7krasvclchrm4aACTBSSH3RAC1P4fgf4FGF15WASF2zgc:86903PIP3pip4k2aaFGF1Acetylcholineim:7150469fgf17LOC558288PIK3CAACTBARPC5pik3c3GRLF1mapk1raf1brock2afgfr2VIL2bdkrb1fgf10aPDGFBpik3r4fgfr3fgf7PFN1Bradykininfgf23LOC555920bcar1fgf3FGF18FGF13MAPK SignalingpathwayCD14fgfr1aBAIAP2PAK6C11orf13FGF11pak2aINS2mapk4fgf12apdgfrbACTG1apcppp1r12apik3cdfgf16PIP5K2CSSH2map2k1ACTBACTG1pak1LOC568935RAC3


Description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r45278) with a 66% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
116903view11:33, 15 May 2021EweitzModified title
72128view07:53, 25 October 2013Mkutmonadded datasource to pathway data nodes
71535view19:23, 17 October 2013MaintBotAutomated update of data sources
68684view05:44, 6 July 2013MaintBotUpdated to 2013 gpml schema
47916view21:38, 18 April 2012KhanspersRemoved redundant information
47915view21:37, 18 April 2012KhanspersUpdating from human to fix xref duplication
40858view22:20, 1 March 2011MaintBotRemoved redundant pathway information and comments
34239view21:40, 9 December 2009MaintBotAutomatic update of empty xrefs
32340view13:34, 15 August 2009MaintBotFixed text labels
31956view13:03, 14 August 2009MaintBotFixed group labels
31386view20:44, 13 August 2009MaintBotFixed text labels
31092view01:38, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACTBGeneProduct
ACTG1GeneProduct
ARHGEF1GeneProduct
ARPC5GeneProduct
AcetylcholineMetabolite51-84-3 (CAS)
Adherens junction pathwayPathway
Apc2GeneProduct
BAIAP2GeneProduct
BradykininMetabolite58-82-2 (CAS)
C11orf13GeneProduct
CD14GeneProduct
CFL1GeneProduct
DIAP1GeneProduct
DIAP3GeneProduct
ENAHGeneProduct
FGF1GeneProduct
FGF11GeneProduct
FGF13GeneProduct
FGF15GeneProduct
FGF18GeneProduct
FGF2GeneProduct
FGF20GeneProduct
FGF21GeneProduct
FGF22GeneProduct
FGF6GeneProduct
FGF9GeneProduct
Focal Adhesion pathwayPathwayWP306
GNG12GeneProduct
GRLF1GeneProduct
INS1GeneProduct
INS2GeneProduct
LOC100149843GeneProduct100149843 (Entrez Gene)
LOC100330960GeneProduct100330960 (Entrez Gene)
LOC100536317GeneProduct100536317 (Entrez Gene)
LOC442775GeneProduct
LOC555920GeneProduct555920 (Entrez Gene)
LOC557176GeneProduct557176 (Entrez Gene)
LOC558288GeneProduct558288 (Entrez Gene)
LOC565130GeneProduct565130 (Entrez Gene)
LOC568935GeneProduct568935 (Entrez Gene)
LOC792708GeneProduct792708 (Entrez Gene)
LPSMetaboliteC00338 (KEGG Compound)
MAP2K2GeneProduct
MAPK Signaling pathwayPathwayWP382
PAK3GeneProduct
PAK6GeneProduct
PDGFAGeneProduct
PDGFBGeneProduct
PFN1GeneProduct
PIK3C2GGeneProduct
PIK3CAGeneProduct
PIP2MetaboliteC04637 (KEGG Compound)
PIP3MetaboliteC05981 (KEGG Compound)
PIP5K2CGeneProduct
RAC1P4GeneProduct
RAC3GeneProduct
ROCK1GeneProduct
SOS1GeneProduct
SSH2GeneProduct
SSH3GeneProduct
TMSB4XGeneProduct
VAV1GeneProduct
VIL2GeneProduct
WASF1GeneProduct
WASF2GeneProduct
actn1GeneProduct560400 (Entrez Gene)
apcGeneProduct386762 (Entrez Gene)
arhgef7aGeneProduct553493 (Entrez Gene)
bcar1GeneProduct568309 (Entrez Gene)
bdkrb1GeneProduct368199 (Entrez Gene)
brafGeneProduct403065 (Entrez Gene)
cdc42lGeneProduct793158 (Entrez Gene)
cfl2GeneProduct403001 (Entrez Gene)
chrm2aGeneProduct352938 (Entrez Gene)
chrm3aGeneProduct571679 (Entrez Gene)
chrm4aGeneProduct100150701 (Entrez Gene)
chrm5aGeneProduct553978 (Entrez Gene)
crkGeneProduct445234 (Entrez Gene)
cskGeneProduct556454 (Entrez Gene)
cyfip2GeneProduct100002872 (Entrez Gene)
dock1GeneProduct572187 (Entrez Gene)
egfGeneProduct403045 (Entrez Gene)
egfraGeneProduct378478 (Entrez Gene)
f2GeneProduct325881 (Entrez Gene)
f2rGeneProduct558477 (Entrez Gene)
fgd1GeneProduct560305 (Entrez Gene)
fgf10aGeneProduct359830 (Entrez Gene)
fgf12aGeneProduct777735 (Entrez Gene)
fgf14GeneProduct497642 (Entrez Gene)
fgf16GeneProduct692065 (Entrez Gene)
fgf17GeneProduct407737 (Entrez Gene)
fgf23GeneProduct494456 (Entrez Gene)
fgf3GeneProduct30549 (Entrez Gene)
fgf4GeneProduct570435 (Entrez Gene)
fgf5GeneProduct494454 (Entrez Gene)
fgf7GeneProduct493181 (Entrez Gene)
fgf8aGeneProduct30538 (Entrez Gene)
fgfr1aGeneProduct30705 (Entrez Gene)
fgfr2GeneProduct352940 (Entrez Gene)
fgfr3GeneProduct58129 (Entrez Gene)
fgfr4GeneProduct100000160 (Entrez Gene)
fn1GeneProduct100005469 (Entrez Gene)
gna12GeneProduct503589 (Entrez Gene)
gna13aGeneProduct326825 (Entrez Gene)
gsnaGeneProduct321099 (Entrez Gene)
im:7150469GeneProduct567938 (Entrez Gene)
iqgap1GeneProduct100002928 (Entrez Gene)
itga1GeneProduct570868 (Entrez Gene)
krasGeneProduct445289 (Entrez Gene)
limk1GeneProduct735292 (Entrez Gene)
map2k1GeneProduct406728 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mapk3GeneProduct399480 (Entrez Gene)
mapk4GeneProduct406782 (Entrez Gene)
mapk6GeneProduct565830 (Entrez Gene)
mosGeneProduct795517 (Entrez Gene)
msnaGeneProduct286739 (Entrez Gene)
msnbGeneProduct553434 (Entrez Gene)
myh10GeneProduct555454 (Entrez Gene)
myl1GeneProduct336165 (Entrez Gene)
mylkbGeneProduct492576 (Entrez Gene)
nckap1GeneProduct561894 (Entrez Gene)
nrasGeneProduct30380 (Entrez Gene)
pak1GeneProduct373103 (Entrez Gene)
pak2aGeneProduct266749 (Entrez Gene)
pak7GeneProduct405898 (Entrez Gene)
pdgfraGeneProduct30745 (Entrez Gene)
pdgfrbGeneProduct559529 (Entrez Gene)
pik3c3GeneProduct548346 (Entrez Gene)
pik3cbGeneProduct100002263 (Entrez Gene)
pik3cdGeneProduct394174 (Entrez Gene)
pik3cgGeneProduct406598 (Entrez Gene)
pik3r2GeneProduct404211 (Entrez Gene)
pik3r3GeneProduct100000252 (Entrez Gene)
pik3r4GeneProduct564088 (Entrez Gene)
pip4k2aaGeneProduct560360 (Entrez Gene)
pip5k1abGeneProduct492549 (Entrez Gene)
pip5k1bbGeneProduct447840 (Entrez Gene)
ppp1r12aGeneProduct445393 (Entrez Gene)
ptk2.1GeneProduct142986 (Entrez Gene)
rac1GeneProduct327204 (Entrez Gene)
rac2GeneProduct415151 (Entrez Gene)
raf1bGeneProduct557109 (Entrez Gene)
rock2aGeneProduct317747 (Entrez Gene)
rras2GeneProduct550513 (Entrez Gene)
rrasGeneProduct449660 (Entrez Gene)
si:ch211-197g15.13GeneProduct798876 (Entrez Gene)
si:dkey-24l11.7GeneProduct571356 (Entrez Gene)
si:dkey-74f15.3GeneProduct559017 (Entrez Gene)
slc9a1GeneProduct795135 (Entrez Gene)
sos2GeneProduct561670 (Entrez Gene)
ssh1bGeneProduct567479 (Entrez Gene)
vclGeneProduct552980 (Entrez Gene)
vil1lGeneProduct393207 (Entrez Gene)
wasbGeneProduct335158 (Entrez Gene)
wu:fc03h05GeneProduct323588 (Entrez Gene)
zgc:114164GeneProduct574004 (Entrez Gene)
zgc:153663GeneProduct767646 (Entrez Gene)
zgc:153713GeneProduct751630 (Entrez Gene)
zgc:86903GeneProduct415187 (Entrez Gene)
zgc:92014GeneProduct431769 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1380"
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