Prostaglandin synthesis and regulation (Rattus norvegicus)
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Cytoplasm
Cortisone
PG Synthases
Inactive Metabolites
Gq signaling
pathway
Cell Membrane
Phospholipids
prolactin
release
Cyp11a1
Cortisol
Ptger3
Prostaglandin H2
Anxa3
TXA2
Ptgfr
Ptgs1
Cortisol
Anxa1
Calcium
Ednrb
S100a10
Scgb1a1
Anxa6
S100a6
Edn1
Ptgir
Pla2g4a
Progesterone
Ednra
PTGDR
PGF2a
Anxa4
Ptgds
Arachidonic Acid
Anxa5
PGF2a
Hsd11b2
Hpgd
Tbxas1
Ptger1
Prl
Ptger4
Anxa2
Ptger2
Hsd11b1
Calcium
Ptgis
Ptgs2
PGI2
ANXA8
PGE2
Description
No description
Comments
GenMAPP notes
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks
See note for more details
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP98(r20887)
with a 80% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
No bibliography
History
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Compare
Revision
Action
Time
User
Comment
117006
view
11:20, 16 May 2021
Eweitz
Modified title
109407
view
18:00, 16 March 2020
L Dupuis
Converted interactions to graphical lines
106976
view
13:43, 17 September 2019
MaintBot
HMDB identifier normalization
71789
view
20:33, 17 October 2013
MaintBot
Automated update of data sources
69399
view
18:59, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67607
view
11:32, 26 June 2013
Ddigles
Ontology Term : 'prostaglandin metabolic pathway' added !
41716
view
02:38, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34095
view
19:17, 9 December 2009
MaintBot
Automatic update of empty xrefs
32392
view
16:59, 15 August 2009
MaintBot
Fixed text labels
32040
view
13:28, 14 August 2009
MaintBot
Fixed group labels
31427
view
21:00, 13 August 2009
MaintBot
Fixed text labels
30941
view
00:40, 30 July 2009
MaintBot
Converted from Homo sapiens
21317
view
11:31, 14 November 2008
MaintBot
[[Pathway:Rattus norvegicus:Prostaglandin synthesis regulation]] moved to [[Pathway:WP303]]: Moved to stable identifier
8346
view
13:46, 7 January 2008
MaintBot
[[Pathway:Rat:Prostaglandin synthesis regulation]] moved to [[Pathway:Rattus norvegicus:Prostaglandin synthesis regulation]]: Renaming species
7791
view
16:17, 18 December 2007
MaintBot
fixed category names
7394
view
12:42, 4 November 2007
MaintBot
Added categories to GPML
6587
view
22:20, 22 May 2007
Nsalomonis
gpml file for [[Rat:Prostaglandin_synthesis_regulation]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ANXA8
GeneProduct
306283 (Entrez Gene)
Anxa1
GeneProduct
25380 (Entrez Gene)
Anxa2
GeneProduct
56611 (Entrez Gene)
Anxa3
GeneProduct
25291 (Entrez Gene)
Anxa4
GeneProduct
79124 (Entrez Gene)
Anxa5
GeneProduct
25673 (Entrez Gene)
Anxa6
GeneProduct
79125 (Entrez Gene)
Arachidonic Acid
Metabolite
Calcium
Metabolite
HMDB00464 (HMDB)
Cortisol
Metabolite
Cyp11a1
GeneProduct
29680 (Entrez Gene)
Edn1
GeneProduct
24323 (Entrez Gene)
PMID: 1474344
Ednra
GeneProduct
24326 (Entrez Gene)
Ednrb
GeneProduct
50672 (Entrez Gene)
Hpgd
GeneProduct
79242 (Entrez Gene)
Hsd11b1
GeneProduct
25116 (Entrez Gene)
Hsd11b2
GeneProduct
25117 (Entrez Gene)
PGE2
Metabolite
HMDB03175 (HMDB)
PGF2a
Metabolite
HMDB01139 (HMDB)
PGI2
Metabolite
HMDB01335 (HMDB)
PTGDR
GeneProduct
498475 (Entrez Gene)
Pla2g4a
GeneProduct
24653 (Entrez Gene)
Prl
GeneProduct
24683 (Entrez Gene)
Progesterone
Metabolite
Prostaglandin H2
Metabolite
Ptgds
GeneProduct
25526 (Entrez Gene)
Ptger1
GeneProduct
25637 (Entrez Gene)
Ptger2
GeneProduct
81752 (Entrez Gene)
Ptger3
GeneProduct
24929 (Entrez Gene)
Ptger4
GeneProduct
84023 (Entrez Gene)
Ptgfr
GeneProduct
25652 (Entrez Gene)
Ptgir
GeneProduct
292661 (Entrez Gene)
Ptgis
GeneProduct
25527 (Entrez Gene)
Ptgs1
GeneProduct
24693 (Entrez Gene)
Ptgs2
GeneProduct
29527 (Entrez Gene)
S100a10
GeneProduct
81778 (Entrez Gene)
PMID: 12962548 relationship with Annexin 2
S100a6
GeneProduct
85247 (Entrez Gene)
Scgb1a1
GeneProduct
25575 (Entrez Gene)
PMID: 7615804, PMID: 3292559
TXA2
Metabolite
HMDB01452 (HMDB)
Tbxas1
GeneProduct
24886 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Discussion
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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External references
DataNodes
Annotated Interactions
No annotated interactions