FAS pathway and stress induction of HSP regulation (Rattus norvegicus)

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Self-activationROS3x-PCytoplasm3x-PPPPathwayInhibitionP3x-PNecrosisMitochondria PathwayApoptosomePPNucleusFAS PathwayPCutPPPNFK-BCell SurvivalProteasomeExtracellularPActivateApoptosisStressCeramidePStress Induction of HSP regulationDNA presentationGlutathionePcasp10FaddArhgdibDaxxMapk8Pak1Map2k4Casp3LmnaHspb1Hspb1LOC498331Casp9Casp8Map3k1Caspase 6DffbTnfactinHspb1Il1aHspb1Tnfsf6Faf1CflarHspb1DffbHspb1Caspase 7Casp8LOC299625CycsMapkapk2Lmnb1Bcl2AdprtApaf1Rb1Apaf1Hspb1Caspase 3Map3k7LOC500417DaxxMapkapk3DNA-PKDffaFaf1RGD:619831Pak2Hspb1Spna1Jun


Description

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Ontology Terms

 

Bibliography

  1. Creagh EM, Sheehan D, Cotter TG; ''Heat shock proteins--modulators of apoptosis in tumour cells.''; Leukemia, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
116961view10:09, 16 May 2021EweitzModified title
109406view17:50, 16 March 2020L DupuisFixed interactions
109386view15:41, 16 March 2020L DupuisConverted interactions to graphical lines
107008view13:46, 17 September 2019MaintBotHMDB identifier normalization
71788view20:32, 17 October 2013MaintBotAutomated update of data sources
69391view18:58, 8 July 2013MaintBotUpdated to 2013 gpml schema
67225view10:23, 26 June 2013Christine ChichesterOntology Term : 'FasL mediated signaling pathway' added !
47779view05:47, 6 April 2012Khanspersupdated xref
41708view02:37, 2 March 2011MaintBotRemoved redundant pathway information and comments
38245view21:23, 27 August 2010KhanspersRemoved receptor and protein complex graphics
35564view15:04, 12 February 2010Thomasadded literature
35559view15:01, 12 February 2010ThomasModified description
34087view19:15, 9 December 2009MaintBotAutomatic update of empty xrefs
33554view09:41, 1 December 2009MaintBotRemoved group label
31581view22:02, 13 August 2009MaintBotFixed text labels
30965view00:47, 30 July 2009MaintBotConverted from Homo sapiens
20869view11:30, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Fas Pathway and Stress Induction of HSP Regulation Biocarta]] moved to [[Pathway:WP89]]: Moved to stable identifier
8020view13:46, 7 January 2008MaintBot[[Pathway:Rat:Fas Pathway and Stress Induction of HSP Regulation Biocarta]] moved to [[Pathway:Rattus norvegicus:Fas Pathway and Stress Induction of HSP Regulation Biocarta]]: Renaming species
7633view16:06, 18 December 2007MaintBotfixed category names
7221view12:41, 4 November 2007MaintBotAdded categories to GPML
6535view22:20, 22 May 2007169.230.77.174gpml file for [[Rat:Fas_Pathway_and_Stress_Induction_of_HSP_Regulation_Biocarta]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AdprtGeneProduct25591 (Entrez Gene)
Apaf1GeneProduct78963 (Entrez Gene)
ArhgdibGeneProduct362456 (Entrez Gene) Interim Symbol: Arhgdib_predicted and Name: Rho, GDP dissociation inhibitor (GDI) beta (predicted)
Bcl2GeneProduct24224 (Entrez Gene)
Casp3GeneProduct25402 (Entrez Gene)
Casp8GeneProduct64044 (Entrez Gene)
Casp9GeneProduct58918 (Entrez Gene)
Caspase 3GeneProductCASP3 (Entrez Gene)
Caspase 6GeneProductCASP6 (Entrez Gene)
Caspase 7GeneProductCASP7 (Entrez Gene)
CflarGeneProduct117279 (Entrez Gene)
CycsGeneProduct25309 (Entrez Gene)
DNA-PKGeneProductRn.24110 (UniGene)
DaxxGeneProduct140926 (Entrez Gene)
DffaGeneProduct114214 (Entrez Gene)
DffbGeneProduct84359 (Entrez Gene)
FaddGeneProduct266610 (Entrez Gene)
Faf1GeneProduct140657 (Entrez Gene)
Hspb1GeneProduct24471 (Entrez Gene)
Il1aGeneProduct24493 (Entrez Gene)
JunGeneProduct24516 (Entrez Gene)
LOC299625GeneProduct299625 (Entrez Gene)
LOC498331GeneProduct498331 (Entrez Gene)
LOC500417GeneProduct500417 (Entrez Gene) receptor (TNFRSF)-interacting serine-threonine kinase 2
LmnaGeneProduct60374 (Entrez Gene)
Lmnb1GeneProduct116685 (Entrez Gene)
Map2k4GeneProduct287398 (Entrez Gene)
Map3k1GeneProduct116667 (Entrez Gene)
Map3k7GeneProduct313121 (Entrez Gene)
Mapk8GeneProduct116554 (Entrez Gene)
Mapkapk2GeneProduct289014 (Entrez Gene)
Mapkapk3GeneProduct315994 (Entrez Gene)
Pak1GeneProduct29431 (Entrez Gene)
Pak2GeneProductPAK2 (Entrez Gene)
RGD:619831GeneProduct246097 (Entrez Gene)
Rb1GeneProduct24708 (Entrez Gene)
Spna1GeneProduct289257 (Entrez Gene) Interim Symbol: Spna1_predicted and Name: spectrin alpha 1 (predicted)
TnfGeneProduct24835 (Entrez Gene)
Tnfsf6GeneProduct25385 (Entrez Gene)
actinGeneProduct
casp10GeneProduct

Annotated Interactions

No annotated interactions

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