Aripiprazole metabolic pathway (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Kubo M, Koue T, Inaba A, Takeda H, Maune H, Fukuda T, Azuma J; ''Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic ARIPIPRAZOLE.''; Drug Metab Pharmacokinet, 2005 PubMed Europe PMC Scholia
2. Spina E, de Leon J; ''Metabolic drug interactions with newer antipsychotics: a comparative review.''; Basic Clin Pharmacol Toxicol, 2007 PubMed Europe PMC Scholia
3. Molden E, Lunde H, Lunder N, Refsum H; ''Pharmacokinetic variability of aripiprazole and the active metabolite dehydroaripiprazole in psychiatric patients.''; Ther Drug Monit, 2006 PubMed Europe PMC Scholia
4. Swainston Harrison T, Perry CM; ''Aripiprazole: a review of its use in schizophrenia and schizoaffective disorder.''; Drugs, 2004 PubMed Europe PMC Scholia
5. Argo TR, Carnahan RM, Perry PJ; ''Aripiprazole, a novel atypical antipsychotic drug.''; Pharmacotherapy, 2004 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	117652	view	11:45, 22 May 2021	Eweitz	Modified title
	106138	view	12:03, 16 August 2019	MaintBot	HMDB identifier normalization
	92286	view	12:34, 19 May 2017	Egonw	Ontology Term : 'xenobiotic metabolic pathway' added !
	79129	view	12:52, 3 March 2015	Egonw	Annotated the Product as a (ChEBI) metabolite (removing a warning about a missing ID).
	77339	view	15:10, 22 August 2014	Egonw	Added a XMetDB identifier for one of the conversions.
	77338	view	15:09, 22 August 2014	Egonw	Use a mim type.
	73981	view	13:28, 13 March 2014	MaintBot	Added two more papers.
	73971	view	07:25, 13 March 2014	MaintBot	Added a reference.
	73897	view	11:22, 2 March 2014	Egonw	Figured out the identity of one of the metabolites.
	73896	view	10:53, 2 March 2014	Egonw	Moved the title closer to the entities, effectively zooming in.
	73895	view	10:52, 2 March 2014	Egonw	Modified description
	73894	view	10:49, 2 March 2014	Egonw	Ontology Term : 'phase I biotransformation pathway via cytochrome P450' added !
	73892	view	10:44, 2 March 2014	Egonw	New pathway

External references

DataNodes

Name	Type	Database reference	Comment
Aripiprazole	Metabolite	HMDB05042 (HMDB)
CYP2D6	GeneProduct	ENSG00000100197 (Ensembl)
CYP3A43	GeneProduct	ENSG00000021461 (Ensembl)
Product	Metabolite

Annotated Interactions

No annotated interactions