Aripiprazole metabolic pathway (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none AripiprazoleProductCYP2D6ProductCYP3A43Name: Aripiprazole Metabolic PathwayOrganism: Homo sapiens


Description

No description

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Quality Tags

Image:Curated.pngReview changes for Approved

Ontology Terms

 

Bibliography

  1. Kubo M, Koue T, Inaba A, Takeda H, Maune H, Fukuda T, Azuma J; ''Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic ARIPIPRAZOLE.''; Drug Metab Pharmacokinet, 2005 PubMed Europe PMC Scholia
  2. Spina E, de Leon J; ''Metabolic drug interactions with newer antipsychotics: a comparative review.''; Basic Clin Pharmacol Toxicol, 2007 PubMed Europe PMC Scholia
  3. Molden E, Lunde H, Lunder N, Refsum H; ''Pharmacokinetic variability of aripiprazole and the active metabolite dehydroaripiprazole in psychiatric patients.''; Ther Drug Monit, 2006 PubMed Europe PMC Scholia
  4. Swainston Harrison T, Perry CM; ''Aripiprazole: a review of its use in schizophrenia and schizoaffective disorder.''; Drugs, 2004 PubMed Europe PMC Scholia
  5. Argo TR, Carnahan RM, Perry PJ; ''Aripiprazole, a novel atypical antipsychotic drug.''; Pharmacotherapy, 2004 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117652
Approved
view11:45, 22 May 2021EweitzModified title
106138view12:03, 16 August 2019MaintBotHMDB identifier normalization
92286view12:34, 19 May 2017EgonwOntology Term : 'xenobiotic metabolic pathway' added !
79129view12:52, 3 March 2015EgonwAnnotated the Product as a (ChEBI) metabolite (removing a warning about a missing ID).
77339view15:10, 22 August 2014EgonwAdded a XMetDB identifier for one of the conversions.
77338view15:09, 22 August 2014EgonwUse a mim type.
73981view13:28, 13 March 2014MaintBotAdded two more papers.
73971view07:25, 13 March 2014MaintBotAdded a reference.
73897view11:22, 2 March 2014EgonwFigured out the identity of one of the metabolites.
73896view10:53, 2 March 2014EgonwMoved the title closer to the entities, effectively zooming in.
73895view10:52, 2 March 2014EgonwModified description
73894view10:49, 2 March 2014EgonwOntology Term : 'phase I biotransformation pathway via cytochrome P450' added !
73892view10:44, 2 March 2014EgonwNew pathway

External references

DataNodes

Name  ↓Type  ↓Database reference  ↓Comment  ↓
AripiprazoleMetaboliteHMDB05042 (HMDB)
CYP2D6GeneProductENSG00000100197 (Ensembl)
CYP3A43GeneProductENSG00000021461 (Ensembl)
ProductMetabolite

Annotated Interactions

No annotated interactions

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