From WikiPathways
ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Opioid Amine Acetylcholine (muscarinic) Somatostatin Adrenoceptors Alpha Adrenoceptors Beta Adrenoceptors Bombesin C5a anaphylatoxin Fmet-leu-phe APJ like Interleukin-8 Chemokine C-C Chemokine C-X-C Chemokine BONZO receptors (CXC6R) CCK Other Chemokine Receptors Endothelin Melanocortin Neuropeptide Y Neuropeptide Y / peptide YY Vasopressin-like Orexin & neuropeptide FF Adrenomedullin (G10D) Chemokine receptor-like Neuromedin U Hormone protein Follicle stimulating hormone Lutropin-choriogonadotropic hormone (Rhod)opsin Rhodopsin Vertebrate Rhodopsin Other Olfactory Nucleotide-like Adenosine Class A Orphan/other Platelet ADP & KI01 receptors SREB Mas proto-oncogene ORPH LGR like (hormone receptors) Purinoceptors Purinoceptor type Y Cannabis Platelet activating factor Thyrotropin-releasing hormone and Secretagogue GPR45 like Thrombin Olfactory Other GP40 like Class A Orphans BDKRB2 BDKRB1 AGTRL1 CX3CR1 F2R FSHR LHCGR P2RY2 PTAFR Dopamine Histamine Serotonin Bradykinin Prostaglandin Angiotensin II Melatonin OPRD1 OPRK1 OPRM1 OPRL1 Group object SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 Group object AVPR2 AVPR1A AVPR1B OXTR GALR1 GALR3 GALR2 F2RL1 F2RL2 F2RL3 Group object HCRTR2 HCRTR1 GPR74 GPR147 Group object OPN3 OPN4 RRH Rgr Group object RHO OPN1MW OPN1LW OPN1SW Group object NMUR2 NMUR1 Group object GPR32 CMKLR1 GPR44 GPR30 Group object GPR37 GPR37L1 Group object OR2T1 OR5U1 OR2AG1 OR12D3 Group object OR7A17 Q9UDD9 OR7C1 OR7A10 OR7A5 OR1Q1 OR1I1 OR1F1 OR1E2 OR1E1 OR1D4 OR1A1 OR1D2 OR1C1 OR1A2 OR7C2 OR1G1 OR2J1 OR10A5 OR10A4 OR2N1P OR5V1 OR2W1 OR2S2 OR2H2 OR2B3 OR2J3 OR2J2 OR2B2 OR2B6 OR2C1 OR2D2 OR2F1 OR2F2 OR2H1 OR2A4 OR3A1 OR3A3 OR3A4 OR8B8 OR8D2 OR5F1 OR5I1 OR6B1 OR11A1 OR6A2 OR10H2 OR10H3 OR10H1 OR10J1 OR1D5 OR3A2 Group object P2RY1 P2RY6 P2RY4 LTB4R GPR92 P2RY11 GPR174 GPR23 P2RY5 P2RY10 GPR35 SUCNR1 Group object ADORA1 ADORA2A ADORA2B ADORA3 Group object PTGER1 PTGER2 PTGDR PTGER3 PTGER4 PTGFR PTGIR TBXA2R Group object CNR2 CNR1 Group object GPR45 CYSLTR1 CYSLTR2 Group object GPR1 GPR31 GPR24 GPR25 GPR12 GPR4 GPR22 GPR15 GPR10 GPR8 GPR7 GPR6 GPR3 GPR52 GPR17 GPR21 GPR19 GPR20 GPR63 Group object GPR43 GPR42 GPR40 GPR41 Group object GPR18 GPR68 GPR34 GPR171 GPR109B MAS1L GPR65 GPR161 GPR75 GPR81 GPR39 Group object MAS1 CMKOR1 Group object GPR27 GPR85 GPR173 Group object P2RY13 GPR87 P2RY12 P2RY14 Group object GPR50 MTNR1A MTNR1B Group object MLNR TRHR GHSR Group object DRD1 DRD5 DRD2 DRD3 DRD4 Group object AGTR1 AGTR2 Group object NMBR BRS3 GRPR Group object ADRB1 ADRB2 ADRB3 Group object ADRA1B ADRA1A ADRA1D ADRA2C ADRA2B ADRA2A Group object CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 Group object HTR1E HTR1F HTR1D HTR1B HTR1A HTR2B HTR2C HTR2A HTR4 HTR5A HTR6 HTR7 Group object HRH1 HRH2 HRH3 Group object CXCR3 CXCR4 BLR1 Group object CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR8 CCR9 CCBP2 CCRL2 Group object IL8RA IL8RB Group object FPRL2 FPR1 FPRL1 Group object C3AR1 GPR77 Group object GPR83 NTSR2 NTSR1 Group object NPY1R NPY2R PPYR1 NPY5R NPY6R Group object MC1R MC2R MC4R MC5R MC3R Group object EDNRA EDNRB Group object CCR10 CCRL1 CCR7 XCR1 Group object CCKAR CCKBR Group object Name: GPCRs, Class A Rhodopsin-like Last Modified: 10/16/2013 Organism: Homo sapiens
Description
This pathway was created using the GPCRDB (Horn et al., 1998),
http://www.cmbi.kun.nl/7tm/ . The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
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Quality Tags
Annotated lists Annotated lists of gene products are considered useful for analysis and for stimulating future pathway curation.
Review changes for Approved Revision 137257 Egon Willighagen .
Ontology Terms
Bibliography
Karchin R, Karplus K, Haussler D; ''Classifying G-protein coupled receptors with support vector machines.''; Bioinformatics, 2002 PubMed Europe PMC Scholia Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, Edvardsen O, Campagne F, Vriend G; ''GPCRDB: an information system for G protein-coupled receptors.''; Nucleic Acids Res, 1998 PubMed Europe PMC Scholia History
External references
DataNodes
Annotated Interactions
No annotated interactions
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