Filamentous growth pathway (Saccharomyces cerevisiae)

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5, 11212827S2817Kss1Hsl7STE20Ste7Cdc42Ste11Cdc24Msb2Yps1101, 131, 13Msb2*1, 2, 41, 1310Sho1Cdc24Sho1Cdc42Msb2*10Msb2*10Cdc42-GTPCdc24Sho1Ste11S2851, 137T286Ste771, 133T363Kss13, 61, 2, 42, 4T183Y18599


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Bibliography

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  1. Roberts RL, Fink GR; ''Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth.''; Genes Dev, 1994 PubMed Europe PMC Scholia
  2. Fujita A, Tonouchi A, Hiroko T, Inose F, Nagashima T, Satoh R, Tanaka S; ''Hsl7p, a negative regulator of Ste20p protein kinase in the Saccharomyces cerevisiae filamentous growth-signaling pathway.''; Proc Natl Acad Sci U S A, 1999 PubMed Europe PMC Scholia
  3. Madhani HD, Styles CA, Fink GR; ''MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation.''; Cell, 1997 PubMed Europe PMC Scholia
  4. Drogen F, O'Rourke SM, Stucke VM, Jaquenoud M, Neiman AM, Peter M; ''Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo.''; Curr Biol, 2000 PubMed Europe PMC Scholia
  5. Zheng CF, Guan KL; ''Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.''; EMBO J, 1994 PubMed Europe PMC Scholia
  6. Neiman AM, Herskowitz I; ''Reconstitution of a yeast protein kinase cascade in vitro: activation of the yeast MEK homologue STE7 by STE11.''; Proc Natl Acad Sci U S A, 1994 PubMed Europe PMC Scholia
  7. Vadaie N, Dionne H, Akajagbor DS, Nickerson SR, Krysan DJ, Cullen PJ; ''''; , PubMed Europe PMC Scholia
  8. Cook JG, Bardwell L, Thorner J; ''Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway.''; Nature, 1997 PubMed Europe PMC Scholia
  9. Sabbagh W Jr, Flatauer LJ, Bardwell AJ, Bardwell L; ''Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation.''; Mol Cell, 2001 PubMed Europe PMC Scholia
  10. Cullen PJ, Sabbagh W Jr, Graham E, Irick MM, van Olden EK, Neal C, Delrow J, Bardwell L, Sprague GF Jr; ''A signaling mucin at the head of the Cdc42- and MAPK-dependent filamentous growth pathway in yeast.''; Genes Dev, 2004 PubMed Europe PMC Scholia
  11. Peter M, Neiman AM, Park HO, van Lohuizen M, Herskowitz I; ''Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast.''; EMBO J, 1996 PubMed Europe PMC Scholia
  12. Leberer E, Wu C, Leeuw T, Fourest-Lieuvin A, Segall JE, Thomas DY; ''Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase.''; EMBO J, 1997 PubMed Europe PMC Scholia
  13. Liu H, Styles CA, Fink GR; ''Elements of the yeast pheromone response pathway required for filamentous growth of diploids.''; Science, 1993 PubMed Europe PMC Scholia

History

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87488view01:38, 25 July 2016AlexanderPicoOntology Term : 'regulatory pathway' added !
87406view11:05, 22 July 2016MaintBotadded missing graphids
77947view19:11, 30 October 2014RnashSpecify description
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External references

DataNodes

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NameTypeDatabase referenceComment
Cdc24GeneProductS000000039 (SGD) Guanine nucleotide exchange factor (GEF)
Cdc42-GTPGeneProductS000004219 (SGD) Cdc24 stimulated, GTP-bound, activated form
Cdc42GeneProductS000004219 (SGD)
Hsl7GeneProductS000000337 (SGD) Arginine N-methyltransferase
Kss1ProteinS000003272 (SGD) MAPK
Msb2*GeneProductS000003246 (SGD) Processed signaling mucin
Msb2GeneProductS000003246 (SGD) Signaling mucin
STE20GeneProductS000000999 (SGD) p21-activated (PAK) kinase
Sho1GeneProductS000000920 (SGD) transmembrane osmosensor
Ste11ProteinS000004354 (SGD) MAPKKK
Ste7ProteinS000002318 (SGD) MAPKK
Yps1GeneProductS000004110 (SGD) Aspartyl protease

Annotated Interactions

No annotated interactions

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