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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none APJ like Interleukin-8 Thrombin Neuromedin U Hormone protein Follicle stimulating hormone Lutropin-choriogonadotropic hormone Thyrotropin Prostacyclin Thromboxane Platelet activating factor Endothelin Amine Acetylcholine (muscarinic) Chrm1 Chrm2 Chrm3 Chrm4 Adrenoceptors Alpha Adrenoceptors Adra1a Adra1b Adra1d Adra2b Adra2c Adra2a Beta Adrenoceptors Adrb1 Adrb2 Adrb3 Peptide Angiotensin Agtr1 Agtr1b Agtr2 Bombesin Nmbr Grpr Brs3 Bradykinin Bdkrb2 Bdkrb1 C5a anaphylatoxin C3ar1 C5r1 Fmet-leu-phe Fpr-rs2 Fpr-rs1 Fpr1 Fprl1 Fpr-rs4 Fpr-rs3 Chemokine C-C Chemokine Ccr1 Ccr1l1 Ccr2 Ccr3 Ccr4 Ccr5 Ccr6 Ccr8 Ccr9 Ccbp2 Ccrl2 C-X-C Chemokine Cxcr3 Cxcr4 Blr1 Cx3cr1 CCK Cckar Cckbr Somatostatin Sstr1 Sstr2 Sstr3 Sstr4 Sstr5 Opioid Oprd1 Oprk1 Oprm1 Oprl1 Neurotensin Ntsr1 Ntsr2 Neuropeptide Y Npy1r Npy2r Ppyr1 Npy5r Npy6r Gpr83 Melanocortin Mc1r Mc2r Mc4r Mc3r Mc5r Vasopressin-like Avpr1a Avpr1b Avp Oxtr Avpr2 Oxt Chemokine receptor-like Gpr33 Cmklr1 Gpr44 Gpr30 Proteinase activated F2rl3 F2rl1 F2rl2 Galanin Galr1 Galr3 Galr2 Rhodopsin Other Rgr Opn4 Rrh Opn3 (Rhod)opsin Rhodopsin Vertebrate Rho Opn1mw Opn1sw Thyrotropin-releasing hormone & Secretagogue Trhr2 Trhr Class A Orphan/other Gpr87 P2ry12 P2ry13 P2ry14 Gpr27 Mas1 Cmkor1 Tcp10c Gpr19 Gpr3 Gpr12 Gpr63 Gpr45 Cysltr1 Gpr65 Gpr34 Gpr109b Cannabis Cnr2 Cnr1 Purinoceptors P2ry2 P2ry1 P2ry6 P2ry4 Gpr35 Ltb4r1 Sucnr1 Nucleotide-like Adenosine Adora2a Adora2b Adora3 Prostanoid Prostaglandin Ptger1 Ptger2 Ptgdr Ptger3 Ptger4 Ptgfr Olfactory type 3 Q9EQ94 Olfr948 Olfr971 Olfr955 Olfr930 Olfr148 Olfr933 Olfr144 Olfr926 Olfr938 Olfr943 Olfr242 Olfr146 Olfr934 Olfr959 Olfr960 Olfr961 Olfr143 Olfr968 Olfr27 Olfr44 Olfr970 Olfr480 Olfr893 Olfr160 Olfr957 Olfr954 Olfr945 Olfr937 Olfr888 Olfr145 Olfr878 Olfr874 Olfr889 Olfr876 Olfr887 Olfr894 Olfr151 Olfr49 Olfr749 Olfr2 Olfr6 Olfr711 Olfr16 Olfr706 Olfr701 Olfr705 Olfr703 Olfr704 Olfr944 Olfr972 Olfactory Olfr19 Olfr1355 Olfr870 Olfr159 Olfr157 Olfr156 Olfr155 Gabbr1 Q9EPG0 Olfr71 Olfr708 Olfr17 Q9EPV1 Olfr716 Olfr715 Olfr713 Olfr15 Olfr707 Olfr714 Olfr710 Olfr70 GPR37 / endothelin B-like Gpr37 Gpr37l1 Agtrl1 Il8rb F2r Nmur1 Fshr Lhcgr Tshr Ptgir Tbxa2r Ptafr Ednrb Histamine Serotonin Dopamine Melatonin Drd3 Drd4 Htr2a Htr2b Htr2c Htr4 Htr5a Htr5b Htr6 Htr7 Hrh1 Hrh2 Htr1b Htr1d Htr1a Htr1f Gpr50 Mtnr1a Group object Name: GPCRs, Class A Rhodopsin-like Organism: Mus musculus
Description
This pathway was created using the GPCRDB (Horn et al., 1998),
http://www.cmbi.kun.nl/7tm/ . The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
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Quality Tags
Annotated lists Annotated lists of gene products are considered useful for analysis and for stimulating future pathway curation.
Review changes for Approved Revision 117889 Martina Kutmon .
Ontology Terms
Bibliography
Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, Edvardsen O, Campagne F, Vriend G; ''GPCRDB: an information system for G protein-coupled receptors.''; Nucleic Acids Res, 1998 PubMed Europe PMC Scholia Karchin R, Karplus K, Haussler D; ''Classifying G-protein coupled receptors with support vector machines.''; Bioinformatics, 2002 PubMed Europe PMC Scholia History
External references
DataNodes
Annotated Interactions
No annotated interactions
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