Nuclear factor, erythroid-derived 2, like 2 signaling pathway (Rattus norvegicus)

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***p62NUCLEUSEXTRACELLULAR SPACECYTOPLASMJNK1/2PI3KMEK1/2PKCERK1/2MKK3/6p21Nfe2l2Gstm3Psmc1Ephx1Bach1FosMap2k6Prkd1Fmo1Sod3PgdAkr7a3Pik3c2gSlc35a2PrkcdMapk3Psmc6Gsta4Abcc4Mapk14Mgst2Dnajb9Keap1AtmActg2Mgst1Pik3r2Pik3r3Gpx2Cacng6Dnajb4Yy1Gstp1Pik3c2aNfe2l2Abcc1Acta1Prdx1Sqstm1Akr7a2Bard1Slc7a11Gsto2GlutathioneSod1MafkAkr1a1Map2k1Me1PrkcbGsrAkt1Sqstm1Bach1Mapk9Aox1Mapk7NrasUbbMap2k7Slc1a4Gstm2Pik3cgActg1Keap1Gstm1Txnrd1Pik3c2bHrasCbr1Psmc5Pik3cbPik3cdPrkcaUgdhHerpud1Xpo1Nqo2NFE2L2 DEGRADATION BY UBIQUITIN PROTEASOMEPsmc4PrkceFosl1RanFosTxn1Map2k2G6pdROSLdhbTp53Mdm2Abcc3KrasAtf4Map2k3Gstt1Gsk3bDnajc5Pik3c3Usp14Taldo1Mapk8Gstm4Pik3caMgst3Rbx1Map3k5Map3k1Gsta1RrasPrkcqTrigonellinePmf1Psmc3Gstt2Atf4MafgJunEif2ak3PrkciMapk1Pik3r6PrkczRaf1Prkcg***CrebbpVcpFth1Hsp90ab1Slc2a1FynGclcGsta2Ep300Brca1ActbGclmActa2Dhcr7Gsto1Smarca4AldoaPrkchGsta3Aldh3a1Psmc2Map3k7Pik3r1Hmox1GssActc1Cul3Gstm5Ub2Gstk1Cdc34Slc35b1Akr1b10MrasCdkn1aNqo1Pik3r4Rras2CebpaDRUGS METABOLISMUV RADIATIONRESPIRATORY BURSTINFLAMATORY CYTOKINESHEAVY METALSPrkd3FtlScarb1Map2k5Sod2Pik3r5MaffUbe2kKeap1Actc1Acta2ActbActa1Actg1Actg2Nfe2l2Nfe2l2


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
125515view02:34, 24 February 2023AlexanderPicoadded description
110698view14:01, 28 May 2020EgonwAdded missing @Type annotation
110697view14:00, 28 May 2020EgonwAdded missing @Type annotation
106970view13:43, 17 September 2019MaintBotHMDB identifier normalization
94539view08:01, 21 September 2017EgonwModified title
91468view03:27, 4 March 2017Richard10Modified title
82999view04:24, 17 November 2015Mkutmonfix outdated identifiers
78474view10:28, 7 January 2015MaintBotadded missing graphIds
71118view00:41, 7 October 2013Richard10Update
71117view00:35, 7 October 2013Richard10Periodical save, work in progress
69742view09:13, 11 July 2013EgonwAdded a ChEBI id for ROS.
68372view03:37, 4 July 2013Richard10progress
68135view11:56, 1 July 2013DdiglesOntology Term : 'nuclear factor, erythroid derived 2, like 2 signaling pathway' added !
58962view18:36, 21 February 2013MaintBotUpdated Ensembl data source
56342view20:39, 5 January 2013MaintBotModified categories
54389view21:57, 28 November 2012Richard10Specify description
54337view03:03, 28 November 2012Richard10Specify description
54336view03:00, 28 November 2012Richard10Periodical save, work in progress
54335view02:57, 28 November 2012Richard10Specify description
54334view02:49, 28 November 2012Richard10New pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
***GeneProduct
Abcc1GeneProduct3112 (RGD)
Abcc3GeneProduct71101 (RGD)
Abcc4GeneProduct620266 (RGD)
Acta1GeneProduct2025 (RGD)
Acta2GeneProduct81633 (Entrez Gene)
ActbGeneProduct628837 (RGD)
Actc1GeneProduct2026 (RGD)
Actg1GeneProduct1304556 (RGD)
Actg2GeneProduct2027 (RGD)
Akr1a1GeneProduct68346 (RGD)
Akr1b10GeneProduct1308277 (RGD)
Akr7a2GeneProduct620311 (RGD)
Akr7a3GeneProduct628635 (RGD)
Akt1GeneProduct2081 (RGD)
Aldh3a1GeneProduct2088 (RGD)
AldoaGeneProduct2089 (RGD)
Aox1GeneProduct54349 (Entrez Gene)
Atf4GeneProduct621863 (RGD)
AtmGeneProduct1593265 (RGD)
Bach1GeneProduct1306693 (RGD)
Bard1GeneProduct621072 (RGD)
Brca1GeneProduct2218 (RGD)
Cacng6GeneProduct628806 (RGD)
Cbr1GeneProduct2286 (RGD)
Cdc34GeneProduct1305411 (RGD)
Cdkn1aGeneProduct69328 (RGD)
CebpaGeneProduct2326 (RGD)
CrebbpGeneProduct2401 (RGD)
Cul3GeneProduct1308190 (RGD)
DRUGS METABOLISM

UV RADIATION RESPIRATORY BURST INFLAMATORY CYTOKINES

HEAVY METALS
Dhcr7GeneProduct621769 (RGD)
Dnajb4GeneProduct1305826 (RGD)
Dnajb9GeneProduct3070 (RGD)
Dnajc5GeneProduct620516 (RGD)
Eif2ak3GeneProduct70884 (RGD)
Ep300GeneProduct170915 (Entrez Gene)
Ephx1GeneProduct2557 (RGD)
Fmo1GeneProduct2622 (RGD)
FosGeneProduct2626 (RGD)
Fosl1GeneProduct2627 (RGD)
Fth1GeneProduct2635 (RGD)
FtlGeneProduct61813 (RGD)
FynGeneProduct2641 (RGD)
G6pdGeneProduct2645 (RGD)
GclcGeneProduct619868 (RGD)
GclmGeneProduct619871 (RGD)
GlutathioneMetaboliteHMDB00125 (HMDB)
Gpx2GeneProduct727780 (RGD)
Gsk3bGeneProduct70982 (RGD)
GsrGeneProduct621747 (RGD)
GssGeneProduct2752 (RGD)
Gsta1GeneProduct2753 (RGD)
Gsta2GeneProduct2754 (RGD)
Gsta3GeneProduct24421 (Entrez Gene)
Gsta4GeneProduct1309970 (RGD)
Gstk1GeneProduct735188 (RGD)
Gstm1GeneProduct2755 (RGD)
Gstm2GeneProduct2756 (RGD)
Gstm3GeneProduct620381 (RGD)
Gstm4GeneProduct1565825 (RGD)
Gstm5GeneProduct61964 (RGD)
Gsto1GeneProduct70952 (RGD)
Gsto2GeneProduct1310764 (RGD)
Gstp1GeneProduct2758 (RGD)
Gstt1GeneProduct2765 (RGD)
Gstt2GeneProduct29487 (Entrez Gene)
Herpud1GeneProduct620818 (RGD)
Hmox1GeneProduct2806 (RGD)
HrasGeneProduct293621 (Entrez Gene)
Hsp90ab1GeneProduct1303075 (RGD)
JunGeneProduct2943 (RGD)
Keap1GeneProduct621619 (RGD)
KrasGeneProduct2981 (RGD)
LdhbGeneProduct2997 (RGD)
MaffGeneProduct1309531 (RGD)
MafgGeneProduct619953 (RGD)
MafkGeneProduct628633 (RGD)
Map2k1GeneProduct70495 (RGD)
Map2k2GeneProduct61888 (RGD)
Map2k3GeneProduct1306620 (RGD)
Map2k5GeneProduct29568 (Entrez Gene)
Map2k6GeneProduct620666 (RGD)
Map2k7GeneProduct1560043 (RGD)
Map3k1GeneProduct620966 (RGD)
Map3k5GeneProduct1306431 (RGD)
Map3k7GeneProduct1309438 (RGD)
Mapk14GeneProduct70496 (RGD)
Mapk1GeneProduct70500 (RGD)
Mapk3GeneProduct3046 (RGD)
Mapk7GeneProduct621505 (RGD)
Mapk8GeneProduct116554 (Entrez Gene)
Mapk9GeneProduct628847 (RGD)
Mdm2GeneProduct1305332 (RGD)
Me1GeneProduct3074 (RGD)
Mgst1GeneProduct70927 (RGD)
Mgst2GeneProduct1311218 (RGD)
Mgst3GeneProduct1306373 (RGD)
MrasGeneProduct3111 (RGD)
NFE2L2

DEGRADATION BY

UBIQUITIN PROTEASOME
Nfe2l2GeneProduct620360 (RGD)
Nqo1GeneProduct2503 (RGD)
Nqo2GeneProduct1303320 (RGD)
NrasGeneProduct3205 (RGD)
PgdGeneProductENSRNOG00000023562 (Ensembl)
Pik3c2aGeneProduct1310389 (RGD)
Pik3c2bGeneProduct1306541 (RGD)
Pik3c2gGeneProduct620231 (RGD)
Pik3c3GeneProduct620899 (RGD)
Pik3caGeneProduct170911 (Entrez Gene)
Pik3cbGeneProduct620917 (RGD)
Pik3cdGeneProduct1310990 (RGD)
Pik3cg GeneProduct1306468 (RGD)
Pik3r1GeneProduct25513 (Entrez Gene)
Pik3r2GeneProduct68341 (RGD)
Pik3r3GeneProduct621042 (RGD)
Pik3r4GeneProduct363131 (Entrez Gene)
Pik3r5GeneProduct1563261 (RGD)
Pik3r6GeneProduct1560850 (RGD)
Pmf1GeneProduct1584694 (RGD)
Prdx1GeneProduct620039 (RGD)
PrkcaGeneProduct3395 (RGD)
PrkcbGeneProduct25023 (Entrez Gene)
PrkcdGeneProduct67383 (RGD)
PrkceGeneProduct61925 (RGD)
PrkcgGeneProduct3397 (RGD)
PrkchGeneProduct621888 (RGD)
PrkciGeneProduct620961 (RGD)
PrkcqGeneProduct620968 (RGD)
PrkczGeneProduct3399 (RGD)
Prkd1GeneProduct620964 (RGD)
Prkd3GeneProduct1310236 (RGD)
Psmc1GeneProduct621097 (RGD)
Psmc2GeneProduct3428 (RGD)
Psmc3GeneProduct61905 (RGD)
Psmc4GeneProduct621102 (RGD)
Psmc5GeneProduct708376 (RGD)
Psmc6GeneProduct1308825 (RGD)
ROSMetaboliteCHEBI:26523 (ChEBI)
Raf1GeneProduct3531 (RGD)
RanGeneProduct620367 (RGD)
Rbx1GeneProduct1308453 (RGD)
RrasGeneProduct1311443 (RGD)
Rras2GeneProduct1310793 (RGD)
Scarb1GeneProduct2302 (RGD)
Slc1a4GeneProduct735146 (RGD)
Slc2a1GeneProduct3704 (RGD)
Slc35a2GeneProduct2293497 (RGD)
Slc35b1GeneProduct727783 (RGD)
Slc7a11GeneProduct1309275 (RGD)
Smarca4GeneProduct621728 (RGD)
Sod1GeneProduct3731 (RGD)
Sod2GeneProduct3732 (RGD)
Sod3GeneProduct3733 (RGD)
Sqstm1GeneProduct113894 (Entrez Gene)
Taldo1GeneProduct620674 (RGD)
Tp53GeneProduct3889 (RGD)
TrigonellineMetaboliteHMDB00875 (HMDB)
Txn1GeneProduct621157 (RGD)
Txnrd1GeneProduct61959 (RGD)
Ub2GeneProduct
UbbGeneProduct192255 (Entrez Gene)
Ube2kGeneProduct1311626 (RGD)
UgdhGeneProduct621879 (RGD)
Usp14GeneProduct1311825 (RGD)
VcpGeneProduct621595 (RGD)
Xpo1GeneProduct620517 (RGD)
Yy1GeneProduct3982 (RGD)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2376"
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