Adipogenesis (Bos taurus)

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1Fully DifferentiatedAdipocyte MarkersInhibitors of Preadipocyte to Adipocyte TransitionInsulin Action GenesTranscription Factors/ModulatorsDifferentiated adipocyteGrowth Factors/HormonesPreadipocyteMiscellaneous FactorsAdipocyte Secretory ProductsPossible Lipodystrophy GenesCYP26B1IL6STAT1RETNEBF1HMGA1GADD45BSTAT5BTWIST1PPARAFZD1KLF5ADPNHIF1ASFRP4SMAD3NR2F1AHRSTAT2KLF7KLF15HNF1ACFDNCOR1PCK2UCP1MEF2ABMP1LPIN1GTF3ALIFREGR2STAT5AIGF1CNTFRMEF2DFRZBRARAADIPOQNCOR2TNFTGFB1RXRAWNT5BLPIN3CDKN1AIRS4FASIRS2BMP3RORABMP4IRS1CUGBP1GADD45AASIPKLF6TRIB3NR3C1SREBF1CEBPDE2F1GATA2MBNL1NR1H3IRS3PCREB1NRIP1ZMPSTE24DVL1SCDCYP26A1GATA4FOXO1GDF10AGPAT2CTNNB1ID3LIPEPPARGC1AOSMLIFPCK1PTGISPRLRWNT1MEF2CSERPINE1CEBPARXRGRB1LMNABMP2NAMPTLEPNCOA2PLIN2DLK1LPLLPIN2SP1MEF2BWWTR1IL6STDDIT3SOCS3STAT6CISD1RBL2NCOA1E2F4FOXC2GH1GATA3AGTSOCS1PPARDMIFMIXL1CEBPBWNT10BSTAT3NDNRBL1INSSLC2A4BSCL2PLIN1EPAS1PPARGSPOCK1


Description

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP236 with a 90% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Rosen ED, Spiegelman BM; ''Molecular regulation of adipogenesis.''; Annu Rev Cell Dev Biol, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
80782view15:25, 30 June 2015Mkutmonhomology conversion
79147view06:11, 5 March 2015KhanspersUpdated conversion from Hs
63401view00:07, 10 May 2013MaintBotUpdated to 2013 gpml schema
40575view19:32, 1 March 2011MaintBotRemoved redundant pathway information and comments
33813view00:22, 9 December 2009MaintBotAutomatic update of empty xrefs
30556view22:01, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ADIPOQGeneProduct282865 (Entrez Gene)
ADPNGeneProduct
AGPAT2GeneProduct512112 (Entrez Gene)
AGTGeneProduct
AHRGeneProduct280714 (Entrez Gene)
ASIPGeneProduct404192 (Entrez Gene)
BMP1GeneProduct510360 (Entrez Gene)
BMP2GeneProduct615037 (Entrez Gene)
BMP3GeneProduct539527 (Entrez Gene)
BMP4GeneProduct407216 (Entrez Gene)
BSCL2GeneProduct513558 (Entrez Gene)
CDKN1AGeneProduct513497 (Entrez Gene)
CEBPAGeneProduct281677 (Entrez Gene)
CEBPBGeneProduct
CEBPDGeneProduct281678 (Entrez Gene)
CFDGeneProduct505647 (Entrez Gene)
CISD1GeneProduct531444 (Entrez Gene)
CNTFRGeneProduct539548 (Entrez Gene)
CREB1GeneProduct281713 (Entrez Gene)
CTNNB1GeneProduct539003 (Entrez Gene)
CUGBP1GeneProduct
CYP26A1GeneProduct539047 (Entrez Gene)
CYP26B1GeneProduct540868 (Entrez Gene)
DDIT3GeneProduct777788 (Entrez Gene)
DLK1GeneProduct
DVL1GeneProduct523325 (Entrez Gene)
E2F1GeneProduct535369 (Entrez Gene)
E2F4GeneProduct525428 (Entrez Gene)
EBF1GeneProduct537712 (Entrez Gene)
EGR2GeneProduct100297981 (Entrez Gene)
EPAS1GeneProduct282711 (Entrez Gene)
FASGeneProduct282488 (Entrez Gene)
FOXC2GeneProduct507300 (Entrez Gene)
FOXO1GeneProduct506618 (Entrez Gene)
FRZBGeneProduct281170 (Entrez Gene)
FZD1GeneProduct445417 (Entrez Gene)
GADD45AGeneProduct505463 (Entrez Gene)
GADD45BGeneProduct618405 (Entrez Gene)
GATA2GeneProduct506809 (Entrez Gene)
GATA3GeneProduct505169 (Entrez Gene)
GATA4GeneProduct327716 (Entrez Gene)
GDF10GeneProduct539510 (Entrez Gene)
GH1GeneProduct
GTF3AGeneProduct100135054 (Entrez Gene)
HIF1AGeneProduct281814 (Entrez Gene)
HMGA1GeneProduct
HNF1AGeneProduct503578 (Entrez Gene)
ID3GeneProduct538690 (Entrez Gene)
IGF1GeneProduct281239 (Entrez Gene)
IL6GeneProduct
IL6STGeneProduct522155 (Entrez Gene)
INSGeneProduct
IRS1GeneProduct538598 (Entrez Gene)
IRS2GeneProduct100300012 (Entrez Gene)
IRS3PGeneProduct
IRS4GeneProduct
KLF15GeneProduct407241 (Entrez Gene)
KLF5GeneProduct535702 (Entrez Gene)
KLF6GeneProduct505884 (Entrez Gene)
KLF7GeneProduct537747 (Entrez Gene)
LEPGeneProduct280836 (Entrez Gene)
LIFGeneProduct280840 (Entrez Gene)
LIFRGeneProduct539504 (Entrez Gene)
LIPEGeneProduct286879 (Entrez Gene)
LMNAGeneProduct404144 (Entrez Gene)
LPIN1GeneProduct537224 (Entrez Gene)
LPIN2GeneProduct514448 (Entrez Gene)
LPIN3GeneProduct521637 (Entrez Gene)
LPLGeneProduct280843 (Entrez Gene)
MBNL1GeneProduct781653 (Entrez Gene)
MEF2AGeneProduct407231 (Entrez Gene)
MEF2BGeneProduct
MEF2CGeneProduct512254 (Entrez Gene)
MEF2DGeneProduct100336730 (Entrez Gene)
MIFGeneProduct280858 (Entrez Gene)
MIXL1GeneProduct614854 (Entrez Gene)
NAMPTGeneProduct520472 (Entrez Gene)
NCOA1GeneProduct525346 (Entrez Gene)
NCOA2GeneProduct508162 (Entrez Gene)
NCOR1GeneProduct507663 (Entrez Gene)
NCOR2GeneProduct538549 (Entrez Gene)
NDNGeneProduct386664 (Entrez Gene)
NR1H3GeneProduct507176 (Entrez Gene)
NR2F1GeneProduct327684 (Entrez Gene)
NR3C1GeneProduct281946 (Entrez Gene)
NRIP1GeneProduct524960 (Entrez Gene)
OSMGeneProduct319086 (Entrez Gene)
PCK1GeneProduct282855 (Entrez Gene)
PCK2GeneProduct282856 (Entrez Gene)
PLIN1GeneProduct520598 (Entrez Gene)
PLIN2GeneProduct280981 (Entrez Gene)
PPARAGeneProduct281992 (Entrez Gene)
PPARDGeneProduct353106 (Entrez Gene)
PPARGGeneProduct281993 (Entrez Gene)
PPARGC1AGeneProduct338446 (Entrez Gene)
PRLRGeneProduct281422 (Entrez Gene)
PTGISGeneProduct282021 (Entrez Gene)
RARAGeneProduct534280 (Entrez Gene)
RB1GeneProduct534712 (Entrez Gene)
RBL1GeneProduct524870 (Entrez Gene)
RBL2GeneProduct533294 (Entrez Gene)
RETNGeneProduct369020 (Entrez Gene)
RORAGeneProduct535597 (Entrez Gene)
RXRAGeneProduct507554 (Entrez Gene)
RXRGGeneProduct509500 (Entrez Gene)
SCDGeneProduct280924 (Entrez Gene)
SERPINE1GeneProduct281375 (Entrez Gene)
SFRP4GeneProduct518004 (Entrez Gene)
SLC2A4GeneProduct282359 (Entrez Gene)
SMAD3GeneProduct515125 (Entrez Gene)
SOCS1GeneProduct518795 (Entrez Gene)
SOCS3GeneProduct282081 (Entrez Gene)
SP1GeneProduct540741 (Entrez Gene)
SPOCK1GeneProduct511211 (Entrez Gene)
SREBF1GeneProduct539361 (Entrez Gene)
STAT1GeneProduct510814 (Entrez Gene)
STAT2GeneProduct511023 (Entrez Gene)
STAT3GeneProduct508541 (Entrez Gene)
STAT5AGeneProduct282375 (Entrez Gene)
STAT5BGeneProduct282376 (Entrez Gene)
STAT6GeneProduct353105 (Entrez Gene)
TGFB1GeneProduct282089 (Entrez Gene)
TNFGeneProduct280943 (Entrez Gene)
TRIB3GeneProduct538465 (Entrez Gene)
TWIST1GeneProduct
UCP1GeneProduct281561 (Entrez Gene)
WNT10BGeneProduct539337 (Entrez Gene)
WNT1GeneProduct540662 (Entrez Gene)
WNT5BGeneProduct508008 (Entrez Gene)
WWTR1GeneProduct614786 (Entrez Gene)
ZMPSTE24GeneProduct538104 (Entrez Gene)

Annotated Interactions

No annotated interactions
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