Vascular smooth muscle contraction (Bos taurus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none DepolarizationCrossbreidgeReduction of intracellular Ca2+ concentrationRELAXCATIONHyperpolarizationIntravasal pressure/stretchContractionMyofilamentsReduction of contractile system Ca2+ sensitivityVasoconstrictors+p-p+pCaDCPI-17RhOAGsIRAGCa2+Calcium signal Pathway20-HETEDAGArachidonateArachidonic acid metabolismIP3CAMPCa2+Ca2+cGMPPKGK+NorepinephrineAngiotensin IIEndothelinvasopressinAdenosinePGI2CGRPAdrenomedullinK+EETANPBNPCNPNOCACNA1CCACNA1DCACNA1FCACNA1SKCNMA1KCNU1KCNMB1KCNMB2KCNMB3KCNMB4CALMCALM3CALM1CALML5CALM2CALML6MYLKMYLK2MYLK3MYLK4ACTA2ACTG2MAP2K1MAP2K2ARAFBRAFRAF1GUCY1A2GUCY1A3GUCY1B3PPP1CCPPP1CAPPP1CBPPP1R12APPP1R12BPPP1R12CMYL6BMYL6MYL9MHCMAPK1MAPK3GNAQGNA11PLCB1PLCB4PLCB3PLCB2CYP4A11CYP4A22PLA2G1BPLA2G2D4PLA2G2D1PLA2G10PLA2G3PLA2G2APLA2G5PLA2G2EPLA2G2APLA2G2CPLA2G2FPLA2G12Aphospholipase A2PLA2G12Bphospholipase A2PLA2G4EPLA2G4BPLA2G4FPLA2G4DPLA2G4APLA2G6ADRA1AADRA1BADRA1DAGTR1EDNRAAVPR1AAVPR1BGNA12GNA13ARHGEF12ARHGEF1ARHGEF11ROCK1ROCK2ADORA2AADORA2BPTGIRCALCRLRAMP1RAMP2RAMP3ADCY1ADCY2ADCY3ADCY4ADCY5ADCY6ADCY7ADCY8ADCY9PRKACAPRKACBPRKXNPR-ANPR-BITPR1ITPR2ITPR3PRKCGPRKCAPRKCBPRKCDPRKCEPRKCHPRKCQCACNA1FCACNA1DCACNA1SCACNA1CKCNMB2KCNU1KCNMB3KCNMB4KCNMB1KCNMA1ITPR2ITPR1ITPR3MYLK2MYLKMYLK4MYLK3MyosinACTG2ACTA2MYL6MHCMYL9MYL6BMyosinPPP1CCPPP1CBPPP1R12CPPP1CAPPP1R12BPPP1R12AVasodilators+p+p+p+p+p+p+p+p-pName: Vascular smooth muscle contractionOrganism: Bos taurus


Description

No description

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Quality Tags

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Image:Curated.pngReview changes for Approved
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Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
107057
Approved
view14:14, 17 September 2019MaintBotChEBI identifier normalization
87857view11:54, 25 July 2016MirellaKalafatiOntology Term : 'regulatory pathway' added !
82870view16:22, 10 November 2015JmeliusCorrect outdated id
80970view12:08, 6 July 2015Mkutmonfixed graphid problem
80968view12:00, 6 July 2015Mkutmonfixed unconnected lines
79750view08:51, 9 April 2015Zarichanged identyfier for CACNA1C
79732view11:42, 7 April 2015ZariModified description
79731view11:34, 7 April 2015ZariNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
20-HETEMetabolite34306 (ChEBI)
ACTA2GeneProduct515610 (Entrez Gene)
ACTG2GeneProduct281595 (Entrez Gene)
ADCY1GeneProduct281601 (Entrez Gene)
ADCY2GeneProduct510708 (Entrez Gene)
ADCY3GeneProduct535603 (Entrez Gene)
ADCY4GeneProduct788151 (Entrez Gene)
ADCY5GeneProduct505740 (Entrez Gene)
ADCY6GeneProduct509936 (Entrez Gene)
ADCY7GeneProduct281603 (Entrez Gene)
ADCY8GeneProduct535017 (Entrez Gene)
ADCY9GeneProduct525482 (Entrez Gene)
ADORA2AGeneProduct617828 (Entrez Gene)
ADORA2BGeneProduct529760 (Entrez Gene)
ADRA1AGeneProduct282134 (Entrez Gene)
ADRA1BGeneProduct407140 (Entrez Gene)
ADRA1DGeneProduct539543 (Entrez Gene)
AGTR1GeneProduct281607 (Entrez Gene)
ANPMetabolite80233 (ChEBI)
ARAFGeneProduct540421 (Entrez Gene)
ARHGEF11GeneProduct511220 (Entrez Gene)
ARHGEF12GeneProduct503575 (Entrez Gene)
ARHGEF1GeneProduct513377 (Entrez Gene)
AVPR1AGeneProduct538439 (Entrez Gene)
AVPR1BGeneProduct282861 (Entrez Gene)
AdenosineMetabolite
AdrenomedullinMetabolite80339 (ChEBI)
Angiotensin IIMetabolite2719 (ChEBI)
ArachidonateMetabolite15843 (ChEBI)
Arachidonic acid metabolismPathway
BNPMetabolite80234 (ChEBI)
BRAFGeneProduct536051 (Entrez Gene)
CACNA1CGeneProduct408015 (Entrez Gene)
CACNA1DGeneProduct408013 (Entrez Gene)
CACNA1FGeneProduct509779 (Entrez Gene)
CACNA1SGeneProduct100337204 (Entrez Gene)
CALCRLGeneProduct527140 (Entrez Gene)
CALM1GeneProduct617095 (Entrez Gene)
CALM2GeneProduct100297344 (Entrez Gene)
CALMGeneProduct326597 (Entrez Gene)
CALM3GeneProduct520277 (Entrez Gene)
CALML5GeneProduct520404 (Entrez Gene)
CALML6GeneProduct617412 (Entrez Gene)
CAMPMetabolite17489 (ChEBI)
CGRPMetabolite80337 (ChEBI)
CNPMetabolite80235 (ChEBI)
CPI-17GeneProduct615348 (Entrez Gene)
CYP4A11GeneProduct511890 (Entrez Gene)
CYP4A22GeneProduct516085 (Entrez Gene)
Ca2+Metabolite29108 (ChEBI)
Ca2+Metabolite29108 (ChEBI)
CaDGeneProduct281660 (Entrez Gene)
Calcium signal PathwayPathway
DAGMetabolite18035 (ChEBI)
EDNRAGeneProduct281749 (Entrez Gene)
EETMetabolite34157 (ChEBI)
EndothelinMetabolite80240 (ChEBI)
GNA11GeneProduct281788 (Entrez Gene)
GNA12GeneProduct515159 (Entrez Gene)
GNA13GeneProduct505611 (Entrez Gene)
GNAQGeneProduct536654 (Entrez Gene)
GUCY1A2GeneProduct613600 (Entrez Gene)
GUCY1A3GeneProduct281216 (Entrez Gene)
GUCY1B3GeneProduct282433 (Entrez Gene)
GsGeneProduct281793 (Entrez Gene)
IP3Metabolite16595 (ChEBI)
IRAGGeneProduct281918 (Entrez Gene)
ITPR1GeneProduct317697 (Entrez Gene)
ITPR2GeneProduct281878 (Entrez Gene)
ITPR3GeneProduct281879 (Entrez Gene)
K+Metabolite29103 (ChEBI)
KCNMA1GeneProduct282573 (Entrez Gene)
KCNMB1GeneProduct407176 (Entrez Gene)
KCNMB2GeneProduct534568 (Entrez Gene)
KCNMB3GeneProduct539609 (Entrez Gene)
KCNMB4GeneProduct520448 (Entrez Gene)
KCNU1GeneProduct524144 (Entrez Gene)
MAP2K1GeneProduct533199 (Entrez Gene)
MAP2K2GeneProduct510434 (Entrez Gene)
MAPK1GeneProduct327672 (Entrez Gene)
MAPK3GeneProduct531391 (Entrez Gene)
MHCGeneProduct
MYL6GeneProduct281341 (Entrez Gene)
MYL6BGeneProduct515421 (Entrez Gene)
MYL9GeneProduct505964 (Entrez Gene)
MYLK2GeneProduct533378 (Entrez Gene)
MYLKGeneProduct338037 (Entrez Gene)
MYLK3GeneProduct526379 (Entrez Gene)
MYLK4GeneProduct518025 (Entrez Gene)
NOMetabolite16480 (ChEBI)
NPR-AGeneProduct533048 (Entrez Gene)
NPR-BGeneProduct281357 (Entrez Gene)
NorepinephrineMetabolite18357 (ChEBI)
PGI2Metabolite15552 (ChEBI)
PKGGeneProduct
PLA2G10GeneProduct613966 (Entrez Gene)
PLA2G12AGeneProduct527214 (Entrez Gene)
PLA2G12BGeneProduct100337447 (Entrez Gene)
PLA2G1BGeneProduct282457 (Entrez Gene)
PLA2G2AGeneProduct507201 (Entrez Gene)
PLA2G2AGeneProduct521383 (Entrez Gene)
PLA2G2CGeneProduct504978 (Entrez Gene)
PLA2G2D1GeneProduct494318 (Entrez Gene)
PLA2G2D4GeneProduct503625 (Entrez Gene)
PLA2G2EGeneProduct506243 (Entrez Gene)
PLA2G2FGeneProduct541294 (Entrez Gene)
PLA2G3GeneProduct527631 (Entrez Gene)
PLA2G4AGeneProduct525072 (Entrez Gene)
PLA2G4BGeneProduct505485 (Entrez Gene)
PLA2G4DGeneProduct531209 (Entrez Gene)
PLA2G4EGeneProduct526364 (Entrez Gene)
PLA2G4FGeneProduct522866 (Entrez Gene)
PLA2G5GeneProduct614911 (Entrez Gene)
PLA2G6GeneProduct535381 (Entrez Gene)
PLCB1GeneProduct287026 (Entrez Gene)
PLCB2GeneProduct508888 (Entrez Gene)
PLCB3GeneProduct515669 (Entrez Gene)
PLCB4GeneProduct281985 (Entrez Gene)
PPP1CAGeneProduct516175 (Entrez Gene)
PPP1CBGeneProduct538829 (Entrez Gene)
PPP1CCGeneProduct282318 (Entrez Gene)
PPP1R12AGeneProduct538606 (Entrez Gene)
PPP1R12BGeneProduct100337338 (Entrez Gene)
PPP1R12CGeneProduct512431 (Entrez Gene)
PRKACAGeneProduct282322 (Entrez Gene)
PRKACBGeneProduct282323 (Entrez Gene)
PRKCAGeneProduct282001 (Entrez Gene)
PRKCBGeneProduct282325 (Entrez Gene)
PRKCDGeneProduct505708 (Entrez Gene)
PRKCEGeneProduct507041 (Entrez Gene)
PRKCGGeneProduct282002 (Entrez Gene)
PRKCHGeneProduct518542 (Entrez Gene)
PRKCQGeneProduct505901 (Entrez Gene)
PRKXGeneProduct505773 (Entrez Gene)
PTGIRGeneProduct520278 (Entrez Gene)
RAF1GeneProduct521196 (Entrez Gene)
RAMP1GeneProduct617017 (Entrez Gene)
RAMP2GeneProduct504230 (Entrez Gene)
RAMP3GeneProduct613547 (Entrez Gene)
ROCK1GeneProduct785911 (Entrez Gene)
ROCK2GeneProduct282041 (Entrez Gene)
RhOAGeneProduct338049 (Entrez Gene)
cGMPMetabolite16356 (ChEBI)
phospholipase A2GeneProduct104974671 (Entrez Gene)
phospholipase A2GeneProduct615045 (Entrez Gene)
vasopressinMetabolite34543 (ChEBI)

Annotated Interactions

No annotated interactions

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