Pyridoxal 5'-phosphate biosynthesis (Oryza sativa)

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cytosolD-erythrose-4-phosphateerythronate-4-phosphatePiPDXPL-GluH+NADHNAD+1-deoxy-D-xylulose5-phosphate1-deoxy-D-xylulose-5-phosphatesynthaseD-glyceraldehyde-3-phosphateO2H+PXLPNAD+H2OH+H2O22-oxo-3-hydroxy-4-phosphobutanoateNADH4-(phosphonooxy)-threoninePYRCO2NAD+CO2(2S)-2-amino-3-oxo-4-phosphonooxybutanoatepyridoxal5'-phosphatesynthaseNADH2OGH2OH+


Description

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History

CompareRevisionActionTimeUserComment
118319view12:23, 26 May 2021EweitzModified title
87622view08:54, 25 July 2016LindarieswijkOntology Term : 'vitamin B6 metabolic pathway' added !
82028view14:40, 8 September 2015Anweshafixing title, data source, & tagging incomplete pathways
80468view14:47, 25 June 2015AnweshaNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
Metabolite
(2S)-2-amino-3-oxo-4-phosphonooxybutanoateMetaboliteCHEBI:16273 (ChEBI)
1-deoxy-D-xylulose 5-phosphateMetaboliteCHEBI:16493 (ChEBI)
1-deoxy-D-xylulose-5-phosphate synthaseProtein1122116 (Reactome) Facilitates the conversion of D-glyceraldehyde-3-phosphate to 1-deoxy-D-xylulose 5-phosphate.
2-oxo-3-hydroxy-4-phosphobutanoateMetaboliteCHEBI:27951 (ChEBI)
2OGMetaboliteCHEBI:30915 (ChEBI)
4-(phosphonooxy)-threonineMetaboliteCHEBI:18336 (ChEBI)
CO2MetaboliteCHEBI:16526 (ChEBI)
D-erythrose-4-phosphateMetaboliteCHEBI:48153 (ChEBI)
D-glyceraldehyde-3-phosphateMetaboliteCHEBI:17138 (ChEBI)
H+MetaboliteCHEBI:15378 (ChEBI)
H2O2MetaboliteCHEBI:16240 (ChEBI)
H2OMetaboliteCHEBI:15377 (ChEBI)
L-GluMetaboliteCHEBI:16015 (ChEBI)
NAD+MetaboliteCHEBI:15846 (ChEBI)
NADHMetaboliteCHEBI:16908 (ChEBI)
O2MetaboliteCHEBI:15379 (ChEBI)
PDXPMetaboliteCHEBI:28803 (ChEBI)
PXLPMetaboliteCHEBI:18405 (ChEBI)
PYRMetaboliteCHEBI:32816 (ChEBI)
PiMetaboliteCHEBI:18367 (ChEBI)
erythronate-4-phosphateMetaboliteCHEBI:49003 (ChEBI)
pyridoxal

5'-phosphate

synthase
Protein1122010 (Reactome) Facilitates the conversion of pyridoxine-5'-phosphate to pyridoxal 5'-phosphate.

Annotated Interactions

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SourceTargetTypeDatabase referenceComment
(2S)-2-amino-3-oxo-4-phosphonooxybutanoate1121389 (Reactome)
(2S)-2-amino-3-oxo-4-phosphonooxybutanoateArrow1120339 (Reactome)
1-deoxy-D-xylulose 5-phosphate1119778 (Reactome)
1-deoxy-D-xylulose 5-phosphateArrow1121157 (Reactome)
1-deoxy-D-xylulose-5-phosphate synthasemim-catalysis1121157 (Reactome)
1119778 (Reactome)
1119816 (Reactome) Erythronate-4-phosphate is converted to 2-oxo-3-hydroxy-4-phosphobutanoate by enzymatic activity of an unknown gene product.
1120086 (Reactome) D-erythrose-4-phosphate is converted to erythronate-4-phosphate by enzymatic activity of an unknown gene product.
1120339 (Reactome) 4-(phosphonooxy)-threonine is converted to (2S)-2-amino-3-oxo-4-phosphonooxybutanoate by enzymatic activity of an unknown gene product.
1120678 (Reactome) 2-oxo-3-hydroxy-4-phosphobutanoate is converted to 4-(phosphonooxy)-threonine by enzymatic activity of an unknown gene product.
1121157 (Reactome) D-glyceraldehyde-3-phosphate is converted to 1-deoxy-D-xylulose 5-phosphate by enzymatic activity of 1-deoxy-D-xylulose-5-phosphate synthase.
1121353 (Reactome) Pyridoxine-5'-phosphate is converted to pyridoxal 5'-phosphate by enzymatic activity of pyridoxal 5'-phosphate synthase.
1121389 (Reactome)
2-oxo-3-hydroxy-4-phosphobutanoate1120678 (Reactome)
2-oxo-3-hydroxy-4-phosphobutanoateArrow1119816 (Reactome)
2OGArrow1120678 (Reactome)
4-(phosphonooxy)-threonine1120339 (Reactome)
4-(phosphonooxy)-threonineArrow1120678 (Reactome)
Arrow1121389 (Reactome)
CO2Arrow1121157 (Reactome)
CO2Arrow1121389 (Reactome)
D-erythrose-4-phosphate1120086 (Reactome)
D-glyceraldehyde-3-phosphate1121157 (Reactome)
H+1121389 (Reactome)
H+Arrow1119816 (Reactome)
H+Arrow1120086 (Reactome)
H+Arrow1120339 (Reactome)
H2O1120086 (Reactome)
H2O2Arrow1121353 (Reactome)
H2OArrow1119778 (Reactome)
L-Glu1120678 (Reactome)
NAD+1119816 (Reactome)
NAD+1120086 (Reactome)
NAD+1120339 (Reactome)
NADHArrow1119816 (Reactome)
NADHArrow1120086 (Reactome)
NADHArrow1120339 (Reactome)
O21121353 (Reactome)
PDXP1121353 (Reactome)
PDXPArrow1119778 (Reactome)
PXLPArrow1121353 (Reactome)
PYR1121157 (Reactome)
PiArrow1119778 (Reactome)
erythronate-4-phosphate1119816 (Reactome)
erythronate-4-phosphateArrow1120086 (Reactome)
pyridoxal

5'-phosphate

synthase
mim-catalysis1121353 (Reactome)
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