Homoserine biosynthesis (Oryza sativa)

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cytosolPiH+L-aspartate-semialdehydeH+L-AspL-aspartyl-4-phosphateNADP+ADPhomoserinedehydrogenaseNAD(P)+homoserineaspartate-semialdehydedehydrogenaseNADPHNAD(P)HATPaspartate kinase


Description

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Ontology Terms

 

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History

CompareRevisionActionTimeUserComment
123819view12:13, 16 August 2022EgonwOntology Term : 'classic metabolic pathway' added !
118285view12:12, 26 May 2021EweitzModified title
82102view14:43, 8 September 2015Anweshafixing title, data source, & tagging incomplete pathways
80484view14:48, 25 June 2015AnweshaNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ADPMetaboliteCHEBI:16761 (ChEBI)
ATPMetaboliteCHEBI:15422 (ChEBI)
H+MetaboliteCHEBI:15378 (ChEBI)
L-AspMetaboliteCHEBI:17053 (ChEBI)
L-aspartate-semialdehydeMetaboliteCHEBI:18051 (ChEBI)
L-aspartyl-4-phosphateMetaboliteCHEBI:15836 (ChEBI)
NAD(P)+MetaboliteREACT_20200 (Reactome)
NAD(P)HMetaboliteREACT_20158 (Reactome)
NADP+MetaboliteCHEBI:18009 (ChEBI)
NADPHMetaboliteCHEBI:16474 (ChEBI)
PiMetaboliteCHEBI:18367 (ChEBI)
aspartate kinaseProtein1121818 (Reactome) Facilitates the conversion of L-aspartate to L-aspartyl-4-phosphate.
aspartate-semialdehyde dehydrogenaseProtein1122213 (Reactome) Facilitates the conversion of L-aspartyl-4-phosphate to L-aspartate-semialdehyde.
homoserine dehydrogenaseProtein1121893 (Reactome) Facilitates the conversion of L-aspartate-semialdehyde to homoserine.
homoserineMetaboliteCHEBI:15699 (ChEBI)

Annotated Interactions

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SourceTargetTypeDatabase referenceComment
1120000 (Reactome) L-aspartate is converted to L-aspartyl-4-phosphate by enzymatic activity of aspartate kinase.
1120265 (Reactome) L-aspartate-semialdehyde is converted to homoserine by enzymatic activity of homoserine dehydrogenase.
1121609 (Reactome) L-aspartyl-4-phosphate is converted to L-aspartate-semialdehyde by enzymatic activity of aspartate-semialdehyde dehydrogenase.
ADPArrow1120000 (Reactome)
ATP1120000 (Reactome)
H+1120265 (Reactome)
H+1121609 (Reactome)
L-Asp1120000 (Reactome)
L-aspartate-semialdehyde1120265 (Reactome)
L-aspartate-semialdehydeArrow1121609 (Reactome)
L-aspartyl-4-phosphate1121609 (Reactome)
L-aspartyl-4-phosphateArrow1120000 (Reactome)
NAD(P)+Arrow1120265 (Reactome)
NAD(P)H1120265 (Reactome)
NADP+Arrow1121609 (Reactome)
NADPH1121609 (Reactome)
PiArrow1121609 (Reactome)
aspartate kinasemim-catalysis1120000 (Reactome)
aspartate-semialdehyde dehydrogenasemim-catalysis1121609 (Reactome)
homoserine dehydrogenasemim-catalysis1120265 (Reactome)
homoserineArrow1120265 (Reactome)
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