Homomethionine biosynthesis (Oryza sativa)

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1-3cytosol2-oxo monocarboxylicacidH2O2-oxo monocarboxylicacid2-oxo-5-methylthiopentanoicacidhomomethionine3-(2'-methylthio)ethylmalic-acidCoA-SHL-alpha-amino acidCO22-(2'-methylthio)ethylmalic-acidL-alpha-amino acid2-oxo-4-methylthiobutanoateL-MetAc-CoA


Description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Wittstock U, Halkier BA.; ''Glucosinolate research in the Arabidopsis era.''; PubMed Europe PMC Scholia
  2. Kroymann J, Textor S, Tokuhisa JG, Falk KL, Bartram S, Gershenzon J, Mitchell-Olds T.; ''A gene controlling variation in Arabidopsis glucosinolate composition is part of the methionine chain elongation pathway.''; PubMed Europe PMC Scholia
  3. Schuster J, Knill T, Reichelt M, Gershenzon J, Binder S.; ''Branched-chain aminotransferase4 is part of the chain elongation pathway in the biosynthesis of methionine-derived glucosinolates in Arabidopsis.''; PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
123818view12:12, 16 August 2022EgonwOntology Term : 'classic metabolic pathway' added !
118626view09:40, 31 May 2021FinterlyFixed KEGG Compound linkout
118303view12:15, 26 May 2021EweitzModified title
82005view14:39, 8 September 2015Anweshafixing title, data source, & tagging incomplete pathways
80488view14:48, 25 June 2015AnweshaNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
2-(2'-methylthio)ethylmalic-acidMetaboliteC17210 (COMPOUND)
2-oxo monocarboxylic acidMetaboliteCHEBI:35910 (ChEBI)
2-oxo-4-methylthiobutanoateMetaboliteCHEBI:33574 (ChEBI)
2-oxo-5-methylthiopentanoic acidMetaboliteC17211 (COMPOUND)
3-(2'-methylthio)ethylmalic-acidMetaboliteC17212 (COMPOUND)
Ac-CoAMetaboliteCHEBI:15351 (ChEBI)
CO2MetaboliteCHEBI:16526 (ChEBI)
CoA-SHMetaboliteCHEBI:15346 (ChEBI)
H2OMetaboliteCHEBI:15377 (ChEBI)
L-MetMetaboliteCHEBI:16643 (ChEBI)
L-alpha-amino acidMetaboliteCHEBI:15705 (ChEBI)
homomethionineMetaboliteCHEBI:50707 (ChEBI)

Annotated Interactions

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SourceTargetTypeDatabase referenceComment
1119783 (Reactome) 2-(2'-methylthio)ethylmalic-acid is converted to 3-(2'-methylthio)ethylmalic-acid by enzymatic activity of an unknown gene product.
1120069 (Reactome) L-methionine is converted to 2-oxo-4-methylthiobutanoate by enzymatic activity of an unknown gene product.
1120432 (Reactome) 2-oxo-4-methylthiobutanoate is converted to 2-(2'-methylthio)ethylmalic-acid by enzymatic activity of an unknown gene product.
1120753 (Reactome) 3-(2'-methylthio)ethylmalic-acid is converted to 2-oxo-5-methylthiopentanoic-acid by enzymatic activity of an unknown gene product.
1120837 (Reactome) 2-oxo-5-methylthiopentanoic-acid is converted to homomethionine by enzymatic activity of an unknown gene product.
2-(2'-methylthio)ethylmalic-acid1119783 (Reactome)
2-(2'-methylthio)ethylmalic-acidArrow1120432 (Reactome)
2-oxo monocarboxylic acid1120069 (Reactome)
2-oxo monocarboxylic acidArrow1120837 (Reactome)
2-oxo-4-methylthiobutanoate1120432 (Reactome)
2-oxo-4-methylthiobutanoateArrow1120069 (Reactome)
2-oxo-5-methylthiopentanoic acid1120837 (Reactome)
2-oxo-5-methylthiopentanoic acidArrow1120753 (Reactome)
3-(2'-methylthio)ethylmalic-acid1120753 (Reactome)
3-(2'-methylthio)ethylmalic-acidArrow1119783 (Reactome)
Ac-CoA1120432 (Reactome)
CO2Arrow1120753 (Reactome)
CoA-SHArrow1120432 (Reactome)
H2O1120432 (Reactome)
L-Met1120069 (Reactome)
L-alpha-amino acid1120837 (Reactome)
L-alpha-amino acidArrow1120069 (Reactome)
homomethionineArrow1120837 (Reactome)
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