Leucine biosynthesis (Zea mays)

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cytosolL-Glu2-isopropyl-3-oxosuccinateL-LeuCoA-SHKIVNADHH+branched-chain-amino-acidtransaminase3-isopropylmalatedehydratase2-isopropylmalate3-isopropylmalateKIC3-isopropylmalatedehydrogenase2OGHomologues of2-isopropylmalatesynthase B(LOC_OS11G04670.1)Ac-CoAH2ONAD+


Description

This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on Ensembl Compara orthology projection. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped ortholog or paralog are inferred to the other species. High-level events are also inferred for these events to allow for easier navigation.<p>Details of projection methods and parameters may be found <a href="/projection.html">here.</a><p>Original Pathway at Reactome: http://www.reactome.org/PathwayBrowser/#DB=gk_current&FOCUS_SPECIES_ID=48887&FOCUS_PATHWAY_ID=5406569</div>

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Quality Tags

Ontology Terms

 

Bibliography

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History

CompareRevisionActionTimeUserComment
123807view12:08, 16 August 2022EgonwOntology Term : 'classic metabolic pathway' added !
118292view12:13, 26 May 2021EweitzModified title
82043view14:40, 8 September 2015Anweshafixing title, data source, & tagging incomplete pathways
80493view14:48, 25 June 2015AnweshaNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2-isopropyl-3-oxosuccinateMetaboliteCHEBI:17214 (ChEBI)
2-isopropylmalateMetaboliteCHEBI:1178 (ChEBI)
2OGMetaboliteCHEBI:30915 (ChEBI)
3-isopropylmalate dehydrataseProtein5405044 (Reactome)
3-isopropylmalate dehydrogenaseProtein5403547 (Reactome)
3-isopropylmalateMetaboliteCHEBI:35121 (ChEBI)
Ac-CoAMetaboliteCHEBI:15351 (ChEBI)
CoA-SHMetaboliteCHEBI:15346 (ChEBI)
H+MetaboliteCHEBI:15378 (ChEBI)
H2OMetaboliteCHEBI:15377 (ChEBI)
Homologues of

2-isopropylmalate synthase B

(LOC_OS11G04670.1)
Protein5404207 (Reactome)
KICMetaboliteCHEBI:17865 (ChEBI)
KIVMetaboliteCHEBI:16530 (ChEBI)
L-GluMetaboliteCHEBI:16015 (ChEBI)
L-LeuMetaboliteCHEBI:15603 (ChEBI)
NAD+MetaboliteCHEBI:15846 (ChEBI)
NADHMetaboliteCHEBI:16908 (ChEBI)
branched-chain-amino-acid transaminaseProtein5404355 (Reactome)

Annotated Interactions

View all...
SourceTargetTypeDatabase referenceComment
2-isopropyl-3-oxosuccinateArrow5403549 (Reactome)
2-isopropylmalate5405046 (Reactome)
2-isopropylmalateArrow5404209 (Reactome)
2OGArrow5405453 (Reactome)
3-isopropylmalate dehydratasemim-catalysis5405046 (Reactome)
3-isopropylmalate dehydrogenasemim-catalysis5403549 (Reactome)
3-isopropylmalate5403549 (Reactome)
3-isopropylmalateArrow5405046 (Reactome)
5403549 (Reactome) This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on Ensembl Compara orthology projection. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped ortholog or paralog are inferred to the other species. High-level events are also inferred for these events to allow for easier navigation.

Details of projection methods and parameters may be found here.


5404209 (Reactome) This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on Ensembl Compara orthology projection. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped ortholog or paralog are inferred to the other species. High-level events are also inferred for these events to allow for easier navigation.

Details of projection methods and parameters may be found here.


5405046 (Reactome) This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on Ensembl Compara orthology projection. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped ortholog or paralog are inferred to the other species. High-level events are also inferred for these events to allow for easier navigation.

Details of projection methods and parameters may be found here.


5405453 (Reactome) This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on Ensembl Compara orthology projection. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped ortholog or paralog are inferred to the other species. High-level events are also inferred for these events to allow for easier navigation.

Details of projection methods and parameters may be found here.


Ac-CoA5404209 (Reactome)
CoA-SHArrow5404209 (Reactome)
H+Arrow5403549 (Reactome)
H2O5404209 (Reactome)
Homologues of

2-isopropylmalate synthase B

(LOC_OS11G04670.1)
mim-catalysis5404209 (Reactome)
KIC5405453 (Reactome)
KIV5404209 (Reactome)
L-Glu5405453 (Reactome)
L-LeuArrow5405453 (Reactome)
NAD+5403549 (Reactome)
NADHArrow5403549 (Reactome)
branched-chain-amino-acid transaminasemim-catalysis5405453 (Reactome)

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