Cap-dependent translation initiation (Oryza sativa)

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cytosolFormation of theternary complex, andsubsequently, the43S complexRibosomal scanningand start codonrecognitionFormation of a poolof free 40S subunitsActivation of themRNA upon binding ofthe cap-bindingcomplex and eIFs,and subsequentbinding to 43SRecycling ofeIF2:GDP


Description

This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on the Ensembl Compara system see also: <a href='http://www.ensembl.org/info/docs/compara/homology_method.html' target='NEW'>Gene orthology/paralogy prediction method.</a>Original Pathway at Reactome: http://www.reactome.org/PathwayBrowser/#DB=gk_current&FOCUS_SPECIES_ID=48887&FOCUS_PATHWAY_ID=1112967</div>

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

CompareRevisionActionTimeUserComment
118295view12:13, 26 May 2021EweitzModified title
82018view14:39, 8 September 2015Anweshafixing title, data source, & tagging incomplete pathways
80518view14:49, 25 June 2015AnweshaNew pathway

External references

DataNodes

NameTypeDatabase referenceComment
Activation of the

mRNA upon binding of the cap-binding complex and eIFs, and subsequent

binding to 43S
Pathway1112963 (Reactome) Developed by Gramene.org
Formation of a pool of free 40S subunitsPathway1112971 (Reactome) Developed by Gramene.org
Formation of the

ternary complex, and subsequently, the

43S complex
Pathway1112990 (Reactome) Developed by Gramene.org
Recycling of eIF2:GDPPathway1112965 (Reactome) Developed by Gramene.org
Ribosomal scanning

and start codon

recognition
Pathway1112968 (Reactome) Developed by Gramene.org

Annotated Interactions

No annotated interactions

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