NAD Biosynthesis I from aspartate (Oryza sativa)

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cytosolO2DA-NAD+L-GlnNH3PRPPCO2H2ODHAPglutamine-dependentNAD(LOC_OS07G07260.1)L-GluNAD+PPinicotinate-nucleotidepyrophosphorylase(LOC_OS09G38060.1)L-AspPiAMPL-aspartate oxidase1 (LOC_OS02G04170.1)H2O2Fe-S metabolismassociated domaincontaining protein(LOC_OS12G19304.1)H2OiminoaspartateATPQUINPPiNicotinateD-ribonucleotideATPPPi


Description

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History

CompareRevisionActionTimeUserComment
118642view12:08, 31 May 2021EweitzModified title
82082view14:42, 8 September 2015Anweshafixing title, data source, & tagging incomplete pathways
80560view14:50, 25 June 2015AnweshaNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AMPMetaboliteCHEBI:16027 (ChEBI)
ATPMetaboliteCHEBI:15422 (ChEBI)
CO2MetaboliteCHEBI:16526 (ChEBI)
DA-NAD+MetaboliteCHEBI:18304 (ChEBI)
DHAPMetaboliteCHEBI:16108 (ChEBI)
Fe-S metabolism

associated domain containing protein

(LOC_OS12G19304.1)
ProteinQ2QTL0 (Uniprot-TrEMBL) Converts iminoaspartate into quinolinate.
H2O2MetaboliteCHEBI:16240 (ChEBI)
H2OMetaboliteCHEBI:15377 (ChEBI)
L-AspMetaboliteCHEBI:17053 (ChEBI)
L-GlnMetaboliteCHEBI:18050 (ChEBI)
L-GluMetaboliteCHEBI:16015 (ChEBI)
L-aspartate oxidase 1 (LOC_OS02G04170.1)ProteinQ6Z836 (Uniprot-TrEMBL) Converts L-aspartate into iminoaspartate.
NAD+MetaboliteCHEBI:15846 (ChEBI)
NH3MetaboliteCHEBI:16134 (ChEBI)
Nicotinate D-ribonucleotideMetaboliteCHEBI:15763 (ChEBI)
O2MetaboliteCHEBI:15379 (ChEBI)
PPiMetaboliteCHEBI:29888 (ChEBI)
PRPPMetaboliteCHEBI:17111 (ChEBI)
PiMetaboliteCHEBI:18367 (ChEBI)
QUINMetaboliteCHEBI:46828 (ChEBI)
glutamine-dependent

NAD

(LOC_OS07G07260.1)
ProteinQ8LI89 (Uniprot-TrEMBL) Converts deamido-NAD into NAD+.
iminoaspartateMetaboliteCHEBI:50616 (ChEBI)
nicotinate-nucleotide

pyrophosphorylase

(LOC_OS09G38060.1)
ProteinQ0IZS0 (Uniprot-TrEMBL) Converts quinolinate into nicotinate nucleotide.

Annotated Interactions

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SourceTargetTypeDatabase referenceComment
1119766 (Reactome) Nicotinate nucleotide is converted into deamido-NAD by enzymatic activity of an unknown gene product.
1119946 (Reactome) Iminoaspartate is converted into quinolinate by enzymatic activity of quinolinate synthatase A.
1119990 (Reactome) Deamido-NAD is converted into NAD+ by enzymatic activity of NAD(+) synthase (glutamine-hydrolyzing).
1120081 (Reactome) Deamido-NAD is converted into NAD+ by enzymatic activity of an uknown gene product.
1120675 (Reactome) L-aspartate is converted into iminoaspartate by enzymatic activity of L-aspartate oxidase.
1121149 (Reactome) Quinolinate is converted into nicotinate nucleotide by enzymatic activity of Nicotinate-nucleotide diphosphorylase (carboxylating).
AMPArrow1119990 (Reactome)
AMPArrow1120081 (Reactome)
ATP1119766 (Reactome)
ATP1119990 (Reactome)
ATP1120081 (Reactome)
CO2Arrow1121149 (Reactome)
DA-NAD+1119990 (Reactome)
DA-NAD+1120081 (Reactome)
DA-NAD+Arrow1119766 (Reactome)
DHAP1119946 (Reactome)
Fe-S metabolism

associated domain containing protein

(LOC_OS12G19304.1)
mim-catalysis1119946 (Reactome)
H2O1119990 (Reactome)
H2O2Arrow1120675 (Reactome)
H2OArrow1119946 (Reactome)
L-Asp1120675 (Reactome)
L-Gln1119990 (Reactome)
L-GluArrow1119990 (Reactome)
L-aspartate oxidase 1 (LOC_OS02G04170.1)mim-catalysis1120675 (Reactome)
NAD+Arrow1119990 (Reactome)
NAD+Arrow1120081 (Reactome)
NH31120081 (Reactome)
Nicotinate D-ribonucleotide1119766 (Reactome)
Nicotinate D-ribonucleotideArrow1121149 (Reactome)
O21120675 (Reactome)
PPiArrow1119766 (Reactome)
PPiArrow1119990 (Reactome)
PPiArrow1120081 (Reactome)
PPiArrow1121149 (Reactome)
PRPP1121149 (Reactome)
PiArrow1119946 (Reactome)
QUIN1121149 (Reactome)
QUINArrow1119946 (Reactome)
glutamine-dependent

NAD

(LOC_OS07G07260.1)
mim-catalysis1119990 (Reactome)
iminoaspartate1119946 (Reactome)
iminoaspartateArrow1120675 (Reactome)
nicotinate-nucleotide

pyrophosphorylase

(LOC_OS09G38060.1)
mim-catalysis1121149 (Reactome)
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