NAD Biosynthesis I from aspartate (Oryza sativa)
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Description
Developed by Gramene.orgOriginal Pathway at Reactome: http://www.reactome.org/PathwayBrowser/#DB=gk_current&FOCUS_SPECIES_ID=48887&FOCUS_PATHWAY_ID=1119384
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
AMP | Metabolite | CHEBI:16027 (ChEBI) | |
ATP | Metabolite | CHEBI:15422 (ChEBI) | |
CO2 | Metabolite | CHEBI:16526 (ChEBI) | |
DA-NAD+ | Metabolite | CHEBI:18304 (ChEBI) | |
DHAP | Metabolite | CHEBI:16108 (ChEBI) | |
Fe-S metabolism
associated domain containing protein (LOC_OS12G19304.1) | Protein | Q2QTL0 (Uniprot-TrEMBL) | Converts iminoaspartate into quinolinate. |
H2O2 | Metabolite | CHEBI:16240 (ChEBI) | |
H2O | Metabolite | CHEBI:15377 (ChEBI) | |
L-Asp | Metabolite | CHEBI:17053 (ChEBI) | |
L-Gln | Metabolite | CHEBI:18050 (ChEBI) | |
L-Glu | Metabolite | CHEBI:16015 (ChEBI) | |
L-aspartate oxidase 1 (LOC_OS02G04170.1) | Protein | Q6Z836 (Uniprot-TrEMBL) | Converts L-aspartate into iminoaspartate. |
NAD+ | Metabolite | CHEBI:15846 (ChEBI) | |
NH3 | Metabolite | CHEBI:16134 (ChEBI) | |
Nicotinate D-ribonucleotide | Metabolite | CHEBI:15763 (ChEBI) | |
O2 | Metabolite | CHEBI:15379 (ChEBI) | |
PPi | Metabolite | CHEBI:29888 (ChEBI) | |
PRPP | Metabolite | CHEBI:17111 (ChEBI) | |
Pi | Metabolite | CHEBI:18367 (ChEBI) | |
QUIN | Metabolite | CHEBI:46828 (ChEBI) | |
glutamine-dependent
NAD (LOC_OS07G07260.1) | Protein | Q8LI89 (Uniprot-TrEMBL) | Converts deamido-NAD into NAD+. |
iminoaspartate | Metabolite | CHEBI:50616 (ChEBI) | |
nicotinate-nucleotide
pyrophosphorylase (LOC_OS09G38060.1) | Protein | Q0IZS0 (Uniprot-TrEMBL) | Converts quinolinate into nicotinate nucleotide. |
Annotated Interactions
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Source | Target | Type | Database reference | Comment |
---|---|---|---|---|
1119766 (Reactome) | Nicotinate nucleotide is converted into deamido-NAD by enzymatic activity of an unknown gene product. | |||
1119946 (Reactome) | Iminoaspartate is converted into quinolinate by enzymatic activity of quinolinate synthatase A. | |||
1119990 (Reactome) | Deamido-NAD is converted into NAD+ by enzymatic activity of NAD(+) synthase (glutamine-hydrolyzing). | |||
1120081 (Reactome) | Deamido-NAD is converted into NAD+ by enzymatic activity of an uknown gene product. | |||
1120675 (Reactome) | L-aspartate is converted into iminoaspartate by enzymatic activity of L-aspartate oxidase. | |||
1121149 (Reactome) | Quinolinate is converted into nicotinate nucleotide by enzymatic activity of Nicotinate-nucleotide diphosphorylase (carboxylating). | |||
AMP | Arrow | 1119990 (Reactome) | ||
AMP | Arrow | 1120081 (Reactome) | ||
ATP | 1119766 (Reactome) | |||
ATP | 1119990 (Reactome) | |||
ATP | 1120081 (Reactome) | |||
CO2 | Arrow | 1121149 (Reactome) | ||
DA-NAD+ | 1119990 (Reactome) | |||
DA-NAD+ | 1120081 (Reactome) | |||
DA-NAD+ | Arrow | 1119766 (Reactome) | ||
DHAP | 1119946 (Reactome) | |||
Fe-S metabolism
associated domain containing protein (LOC_OS12G19304.1) | mim-catalysis | 1119946 (Reactome) | ||
H2O | 1119990 (Reactome) | |||
H2O2 | Arrow | 1120675 (Reactome) | ||
H2O | Arrow | 1119946 (Reactome) | ||
L-Asp | 1120675 (Reactome) | |||
L-Gln | 1119990 (Reactome) | |||
L-Glu | Arrow | 1119990 (Reactome) | ||
L-aspartate oxidase 1 (LOC_OS02G04170.1) | mim-catalysis | 1120675 (Reactome) | ||
NAD+ | Arrow | 1119990 (Reactome) | ||
NAD+ | Arrow | 1120081 (Reactome) | ||
NH3 | 1120081 (Reactome) | |||
Nicotinate D-ribonucleotide | 1119766 (Reactome) | |||
Nicotinate D-ribonucleotide | Arrow | 1121149 (Reactome) | ||
O2 | 1120675 (Reactome) | |||
PPi | Arrow | 1119766 (Reactome) | ||
PPi | Arrow | 1119990 (Reactome) | ||
PPi | Arrow | 1120081 (Reactome) | ||
PPi | Arrow | 1121149 (Reactome) | ||
PRPP | 1121149 (Reactome) | |||
Pi | Arrow | 1119946 (Reactome) | ||
QUIN | 1121149 (Reactome) | |||
QUIN | Arrow | 1119946 (Reactome) | ||
glutamine-dependent
NAD (LOC_OS07G07260.1) | mim-catalysis | 1119990 (Reactome) | ||
iminoaspartate | 1119946 (Reactome) | |||
iminoaspartate | Arrow | 1120675 (Reactome) | ||
nicotinate-nucleotide
pyrophosphorylase (LOC_OS09G38060.1) | mim-catalysis | 1121149 (Reactome) |