GA12 biosynthesis (Oryza sativa)

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cytosolNADPHNADPHH2OH2Oent-7-alpha-hydroxykaurenoateO2NADPHNADP+H+O2H+O2H+H+H+H+Ent-kaurenoic acidoxidase(LOC_OS06G02019.1)Ent-kaurene oxidaseGA12-aldehydeO2O2GA12H2ONADP+ent-kaur-16-eneH2ONADPHH2ONADP+NADP+ent-kaur-16-en-19-alNADPHent-kaurenoateNADPHH2Oent-kaur-16-en-19-olNADP+NADP+O2


Description

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History

CompareRevisionActionTimeUserComment
118253view12:05, 26 May 2021EweitzModified title
82041view14:40, 8 September 2015Anweshafixing title, data source, & tagging incomplete pathways
80569view14:51, 25 June 2015AnweshaNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
Ent-kaurene oxidaseProtein2731025 (Reactome) Catalyzes the conversion of ent-kaur-16-ene into ent-kaur-16-en-19-ol.
Ent-kaurenoic acid

oxidase

(LOC_OS06G02019.1)		ProteinQ5VRM7 (Uniprot-TrEMBL) Catalyzes the conversion of ent-kaurenoate into ent-7-alpha-hydroxykaurenoate.
GA12-aldehydeMetaboliteCHEBI:15610 (ChEBI)
GA12MetaboliteCHEBI:30088 (ChEBI)
H+MetaboliteCHEBI:15378 (ChEBI)
H2OMetaboliteCHEBI:15377 (ChEBI)
NADP+MetaboliteCHEBI:18009 (ChEBI)
NADPHMetaboliteCHEBI:16474 (ChEBI)
O2MetaboliteCHEBI:15379 (ChEBI)
ent-7-alpha-hydroxykaurenoateMetaboliteCHEBI:15419 (ChEBI)
ent-kaur-16-en-19-alMetaboliteCHEBI:15418 (ChEBI)
ent-kaur-16-en-19-olMetaboliteCHEBI:15416 (ChEBI)
ent-kaur-16-eneMetaboliteCHEBI:15415 (ChEBI)
ent-kaurenoateMetaboliteCHEBI:15417 (ChEBI)

Annotated Interactions

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SourceTargetTypeDatabase referenceComment
1119763 (Reactome) Ent-7-alpha-hydroxykaurenoate is converted into GA12-aldehyde by enzymatic activity of ent-kaurenoate oxidase.
1120253 (Reactome) Ent-kaur-16-en-19-al is converted into ent-kaurenoate by enzymatic ativity of ent-kaurene oxidase.
1120539 (Reactome) Ent-kaur-16-en-19-ol is converted into ent-kaur-16-en-19-al by enzymatic ativity of ent-kaurene oxidase.
1120950 (Reactome) GA12-aldehyde is converted into GA12 by enzymatic activity of ent-kaurenoate oxidase.
1120957 (Reactome) Ent-kaur-16-ene is converted into ent-kaur-16-en-19-ol by enzymatic activity of ent-kaurene oxidase.
1121097 (Reactome) Ent-kaurenoate is converted into ent-7-alpha-hydroxykaurenoate by enzymatic activity of ent-kaurene oxidase.
Ent-kaurene oxidasemim-catalysis1120253 (Reactome)
Ent-kaurene oxidasemim-catalysis1120539 (Reactome)
Ent-kaurene oxidasemim-catalysis1120957 (Reactome)
Ent-kaurenoic acid

oxidase

(LOC_OS06G02019.1)		mim-catalysis1119763 (Reactome)
Ent-kaurenoic acid

oxidase

(LOC_OS06G02019.1)		mim-catalysis1120950 (Reactome)
Ent-kaurenoic acid

oxidase

(LOC_OS06G02019.1)		mim-catalysis1121097 (Reactome)
GA12-aldehyde1120950 (Reactome)
GA12-aldehydeArrow1119763 (Reactome)
GA12Arrow1120950 (Reactome)
H+1119763 (Reactome)
H+1120253 (Reactome)
H+1120539 (Reactome)
H+1120950 (Reactome)
H+1120957 (Reactome)
H+1121097 (Reactome)
H2OArrow1119763 (Reactome)
H2OArrow1120253 (Reactome)
H2OArrow1120539 (Reactome)
H2OArrow1120950 (Reactome)
H2OArrow1120957 (Reactome)
H2OArrow1121097 (Reactome)
NADP+Arrow1119763 (Reactome)
NADP+Arrow1120253 (Reactome)
NADP+Arrow1120539 (Reactome)
NADP+Arrow1120950 (Reactome)
NADP+Arrow1120957 (Reactome)
NADP+Arrow1121097 (Reactome)
NADPH1119763 (Reactome)
NADPH1120253 (Reactome)
NADPH1120539 (Reactome)
NADPH1120950 (Reactome)
NADPH1120957 (Reactome)
NADPH1121097 (Reactome)
O21119763 (Reactome)
O21120253 (Reactome)
O21120539 (Reactome)
O21120950 (Reactome)
O21120957 (Reactome)
O21121097 (Reactome)
ent-7-alpha-hydroxykaurenoate1119763 (Reactome)
ent-7-alpha-hydroxykaurenoateArrow1121097 (Reactome)
ent-kaur-16-en-19-al1120253 (Reactome)
ent-kaur-16-en-19-alArrow1120539 (Reactome)
ent-kaur-16-en-19-ol1120539 (Reactome)
ent-kaur-16-en-19-olArrow1120957 (Reactome)
ent-kaur-16-ene1120957 (Reactome)
ent-kaurenoate1121097 (Reactome)
ent-kaurenoateArrow1120253 (Reactome)
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