Osteopontin signaling (Bos taurus)
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1
IkBa
MMP-9 mRNA
P
P
?
IkBa degradation
P
uPA mRNA
IkBa
Pro - MMP-9
P
P
NFKB1
NFKB1
MAPK1
IKBKB
MAP2K1
CHUK
ITGAV
RELA
RELA
PLAU
NIK
MMP9
SPP1
NFKB1
INTB3
NIK
MAPK3
RELA
RELA
NFKB1
Description
Study of regulation of promatrix metalloproteinase-9 (MMP-9) by osteopontin (OPN) through IKK signaling pathway.
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP1434(78545)
with a 90.0% conversion rate.
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Bibliography
Das R, Philip S, Mahabeleshwar GH, Bulbule A, Kundu GC; ''Osteopontin: it's role in regulation of cell motility and nuclear factor kappa B-mediated urokinase type plasminogen activator expression.''; IUBMB Life, 2005
PubMed
Europe PMC
Scholia
History
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Time
User
Comment
117585
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11:24, 21 May 2021
Eweitz
Modified title
80722
view
15:23, 30 June 2015
Mkutmon
New pathway
External references
DataNodes
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Name
Type
Database reference
Comment
CHUK
GeneProduct
ENSBTAG00000007591 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1147
IKBKB
GeneProduct
ENSBTAG00000007599 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3551
INTB3
GeneProduct
ENSBTAG00000009987 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3690
ITGAV
GeneProduct
ENSBTAG00000019929 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3685
MAP2K1
GeneProduct
ENSBTAG00000033983 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5604
MAPK1
GeneProduct
ENSBTAG00000010312 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5594
MAPK3
GeneProduct
ENSBTAG00000016156 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5595
MMP9
GeneProduct
ENSBTAG00000020676 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4318
NFKB1
GeneProduct
ENSBTAG00000020270 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4790
NIK
GeneProduct
PLAU
GeneProduct
ENSBTAG00000005947 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5328
RELA
GeneProduct
ENSBTAG00000013895 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5970
SPP1
GeneProduct
ENSBTAG00000005260 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6696
Annotated Interactions
No annotated interactions
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