Parkin-ubiquitin proteasomal system pathway (Bos taurus)
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UBC7
Tubulin beta
26S Proteasome (19S regulator)
UBC6
Tubulin alpha
HSP70
TUBB8
TUBA4A
HSPA8
UBA1
PSMD8
UBE2J2
UBE2L3
UBE2G2
UBE2J1
UBE2G1
UBE2L6
Proteasomal Degradation
Caspase-1
SEPT5
CCNE1
CUL1
TUBAL3
PSMD11
FBXW7
PARK2
SNCAIP
CASK
CASP8
STUB1
GPR37
SNCA
SIAH1
RNF19A
SIAH2
TUBA3E
TUBA3D
TUBA3C
TUBA1C
TUBA1B
TUBA1A
TUBA8
TUBA4B
TUBB6
TUBB4Q
TUBB4A
TUBB3
TUBB4B
TUBB2B
TUBB2B
TUBB1
TUBB5
PSMD10
PSMD1
PSMC6
PSMC5
PSMC4
PSMC3
PSMC2
PSMC1
PSMD7
PSMD6
PSMD5
PSMD4
PSMD3
PSMD2
PSMD14
PSMD13
PSMD12
PSMD9
HSPA7
HSPA6
GRP78
HSPA4
HSPA2
HSPA1L
HSPA1B
HSPA1A
HSPA14
HSPA9
Description
This pathway describes the Parkin-Ubiquitin proteasome degradation system.
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP2359(72121)
with a 84.0% conversion rate.
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View approved pathways at
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Smith SB, Dampier W, Tozeren A, Brown JR, Magid-Slav M; ''Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis.''; PLoS One, 2012
PubMed
Europe PMC
Scholia
History
Compare
Revision
Action
Time
User
Comment
117587
view
11:24, 21 May 2021
Eweitz
Modified title
80786
view
15:26, 30 June 2015
Mkutmon
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
CASK
GeneProduct
ENSBTAG00000020136 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8573
CASP8
GeneProduct
ENSBTAG00000015718 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:841
CCNE1
GeneProduct
ENSBTAG00000004735 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:898
CUL1
GeneProduct
ENSBTAG00000008736 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8454
Caspase-1
GeneProduct
FBXW7
GeneProduct
ENSBTAG00000007953 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55294
GPR37
GeneProduct
ENSBTAG00000013732 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2861
GRP78
GeneProduct
ENSBTAG00000007662 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3309
HSPA14
GeneProduct
ENSBTAG00000016451 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51182
HSPA1A
GeneProduct
HomologyConvert: Multiple homologues found: En:ENSBTAG00000025441;En:ENSBTAG00000025441;
HSPA1B
GeneProduct
HomologyConvert: Multiple homologues found: En:ENSBTAG00000025441;En:ENSBTAG00000025441;
HSPA1L
GeneProduct
ENSBTAG00000025442 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3305
HSPA2
GeneProduct
HSPA4
GeneProduct
ENSBTAG00000015683 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3308
HSPA6
GeneProduct
ENSBTAG00000039035 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3310
HSPA7
GeneProduct
HSPA8
GeneProduct
ENSBTAG00000013162 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3312
HSPA9
GeneProduct
ENSBTAG00000011419 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3313
PARK2
GeneProduct
ENSBTAG00000018996 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5071
PSMC1
GeneProduct
ENSBTAG00000005426 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5700
PSMC2
GeneProduct
ENSBTAG00000046712 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5701
PSMC3
GeneProduct
ENSBTAG00000021744 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5702
PSMC4
GeneProduct
ENSBTAG00000009414 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5704
PSMC5
GeneProduct
ENSBTAG00000021061 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5705
PSMC6
GeneProduct
ENSBTAG00000015732 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5706
PSMD10
GeneProduct
ENSBTAG00000013721 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5716
PSMD11
GeneProduct
ENSBTAG00000018897 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5717
PSMD12
GeneProduct
ENSBTAG00000002423 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5718
PSMD13
GeneProduct
ENSBTAG00000002045 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5719
PSMD14
GeneProduct
ENSBTAG00000021691 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10213
PSMD1
GeneProduct
ENSBTAG00000005119 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5707
PSMD2
GeneProduct
ENSBTAG00000005660 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5708
PSMD3
GeneProduct
ENSBTAG00000021461 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5709
PSMD4
GeneProduct
ENSBTAG00000006101 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5710
PSMD5
GeneProduct
ENSBTAG00000016952 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5711
PSMD6
GeneProduct
ENSBTAG00000015112 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9861
PSMD7
GeneProduct
ENSBTAG00000018425 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5713
PSMD8
GeneProduct
ENSBTAG00000031641 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5714
PSMD9
GeneProduct
HomologyConvert: Multiple homologues found: En:ENSBTAG00000004179;En:ENSBTAG00000004179;
Proteasomal Degradation
Pathway
WP183 (WikiPathways)
RNF19A
GeneProduct
ENSBTAG00000017833 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:25897
SEPT5
GeneProduct
ENSBTAG00000008320 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5413
SIAH1
GeneProduct
ENSBTAG00000010868 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6477
SIAH2
GeneProduct
ENSBTAG00000023445 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6478
SNCA
GeneProduct
ENSBTAG00000024957 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6622
SNCAIP
GeneProduct
ENSBTAG00000021971 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9627
STUB1
GeneProduct
ENSBTAG00000019136 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10273
TUBA1A
GeneProduct
ENSBTAG00000001489 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7846
TUBA1B
GeneProduct
ENSBTAG00000012244 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10376
TUBA1C
GeneProduct
ENSBTAG00000039992 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:84790
TUBA3C
GeneProduct
HomologyConvert: Multiple homologues found: En:ENSBTAG00000030979;En:ENSBTAG00000030979;
TUBA3D
GeneProduct
HomologyConvert: Multiple homologues found: En:ENSBTAG00000030979;En:ENSBTAG00000030979;
TUBA3E
GeneProduct
ENSBTAG00000030979 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:112714
TUBA4A
GeneProduct
ENSBTAG00000030974 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7277
TUBA4B
GeneProduct
TUBA8
GeneProduct
ENSBTAG00000018530 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51807
TUBAL3
GeneProduct
ENSBTAG00000017740 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:79861
TUBB1
GeneProduct
ENSBTAG00000018785 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:81027
TUBB2B
GeneProduct
ENSBTAG00000004093 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:347733
TUBB2B
GeneProduct
ENSBTAG00000046886 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7280
TUBB3
GeneProduct
ENSBTAG00000023730 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10381
TUBB4A
GeneProduct
ENSBTAG00000021013 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10382
TUBB4B
GeneProduct
ENSBTAG00000025274 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10383
TUBB4Q
GeneProduct
TUBB5
GeneProduct
ENSBTAG00000006969 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:203068
TUBB6
GeneProduct
ENSBTAG00000046337 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:84617
TUBB8
GeneProduct
UBA1
GeneProduct
ENSBTAG00000016764 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7317
UBE2G1
GeneProduct
ENSBTAG00000014433 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7326
UBE2G2
GeneProduct
ENSBTAG00000048090 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7327
UBE2J1
GeneProduct
ENSBTAG00000018436 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51465
UBE2J2
GeneProduct
ENSBTAG00000015882 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:118424
UBE2L3
GeneProduct
ENSBTAG00000013038 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7332
UBE2L6
GeneProduct
ENSBTAG00000012989 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9246
Annotated Interactions
No annotated interactions
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No annotated interactions