Alanine and aspartate metabolism (Bos taurus)

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1, 2Citrate cycle (TCA cycle)ProteinL-Alanyl-tRNAFatty acid metabolismAGXTGAD1Pyrimidine metabolismDARSN-Carbamoyl-L-aspartate3.5.1.3L-ArgininosuccinateFumarateASPAABAT1.4.3.16Nicotinate and nicotinamide metabolismNicotinate and nicotinamide metabolismMalatetRNA (Asn)Glycine, serine and threonine metabolismO-Acetylcarnitine2.6.1.14beta-Alanine metabolismArginine and Proline metabolism1.4.3.15D-aspartatePCAdenylosuccinate1.4.3.2Cyanoamino acid metabolismL-Alanine6.3.5.63.4.13.3D-Ala metabolismL-AsparagineGOT1L-Asparagine acid6.1.1.7L-Asparagine acidtRNA (Asn)2-Oxoglutarate5.1.1.16.3.2.114.3.1.12-Oxosuccinamate6.3.5.42.6.1.184.3.2.23.5.1.73.5.1.382.6.1.12Lysine biosynthesis2.1.3.2Pantothenate and CoA biosynthesis4.1.1.126.3.4.4Histidine metabolismtRNA(Asp)Selenoamino acid metabolismL-Aspartic acidReductive carboxylate cycle (CO2 fixation)Glycolysis & gluconeogenesisDARSOxaloacetateSuccinate5.1.1.13N-Acetyl-L-aspartate1.4.3.1L-aspartateGAD2Urea cycel and metabolism of amino groupsAcetyl-CoACarnosine6.3.1.1Citric acidReductive carboxylatecycle (CO2 fixation)D-Alanine4.1.1.111.2.1.18GOT23.5.1.1ASS1GPTPyruvate6.1.1.22Malonate semialdehyde2.3.1.7b-AlanineASL


Description

No description

Comments

GenMAPP notes 
Converted from rat to human using ortholog information. Link to original KEGG map: http://www.genome.ad.jp/dbget-bin/show pathway?rno00252
GenMAPP remarks 
Edited by Sebastien Burel.
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP106(74147) with a 29.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Wu G; ''Intestinal mucosal amino acid catabolism.''; J Nutr, 1998 PubMed Europe PMC Scholia
  2. Curien G, Bastien O, Robert-Genthon M, Cornish-Bowden A, Cárdenas ML, Dumas R; ''Understanding the regulation of aspartate metabolism using a model based on measured kinetic parameters.''; Mol Syst Biol, 2009 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123267view09:07, 9 July 2022EgonwMade three pathways clickable
107073view14:16, 17 September 2019MaintBotChEBI identifier normalization
105967view11:49, 16 August 2019MaintBotHMDB identifier normalization
102419view10:03, 23 December 2018EgonwReplaced a deleted CAS number with the active one.
92990view18:16, 21 July 2017Khanspersfixed unconnected
92989view18:11, 21 July 2017KhanspersModified description
92988view18:10, 21 July 2017Khanspersremoved GenMAPP notes
92895view19:09, 14 July 2017EgonwReplace a CAS number for a totally different compound with the ChEBI ID for L-alanine.
80904view15:30, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1.2.1.18GeneProduct
1.4.3.1GeneProduct
1.4.3.15GeneProduct
1.4.3.16GeneProduct
1.4.3.2GeneProduct
2-OxoglutarateMetaboliteC00026 (KEGG Compound)
2-OxosuccinamateMetabolite
2.1.3.2GeneProduct
2.3.1.7GeneProduct
2.6.1.12GeneProduct
2.6.1.14GeneProduct
2.6.1.18GeneProduct
3.4.13.3GeneProduct
3.5.1.1GeneProduct
3.5.1.3GeneProduct
3.5.1.38GeneProduct
3.5.1.7GeneProduct
4.1.1.11GeneProduct
4.1.1.12GeneProduct
4.3.1.1GeneProduct
4.3.2.2GeneProduct
5.1.1.1GeneProduct
5.1.1.13GeneProduct
6.1.1.22GeneProduct
6.1.1.7GeneProduct
6.3.1.1GeneProduct
6.3.2.11GeneProduct
6.3.4.4GeneProduct
6.3.5.4GeneProduct
6.3.5.6GeneProduct
ABATGeneProductENSBTAG00000004038 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:18
AGXTGeneProductENSBTAG00000005797 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:189
ASLGeneProductENSBTAG00000015314 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:435
ASPAGeneProductENSBTAG00000003629 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:443
ASS1GeneProductENSBTAG00000020747 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:445
Acetyl-CoAMetabolite72-89-9 (CAS) Acetyl-CoA
AdenylosuccinateMetabolite
Arginine and Proline metabolismPathway
CarnosineMetabolite305-84-0 (CAS) Carnosine
Citric acidMetaboliteHMDB00094 (HMDB)
Cyanoamino acid metabolismPathway
D-Ala metabolismPathway
D-AlanineMetabolite338-69-2 (CAS) D-Alanine
D-aspartateMetaboliteC00402 (KEGG Compound)
DARSGeneProductENSBTAG00000009949 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1615
Fatty acid metabolismPathwayWP143 (WikiPathways)
FumarateMetaboliteC00122 (KEGG Compound)
GAD1GeneProductENSBTAG00000007258 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2571
GAD2GeneProductENSBTAG00000008056 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2572
GOT1GeneProductENSBTAG00000011960 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2805
GOT2GeneProductENSBTAG00000007172 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2806
GPTGeneProductENSBTAG00000007835 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2875
Glycine, serine and threonine metabolismPathway
Glycolysis & gluconeogenesisPathwayWP534 (WikiPathways)
Histidine metabolismPathway
L-AlanineMetabolite6912-68-1 (CAS)
L-ArgininosuccinateMetaboliteCHEBI:15682 (ChEBI)
L-Asparagine acidMetabolite70-47-3 (CAS)
L-AsparagineMetabolite70-47-3 (CAS) L-Asparagine
L-Aspartic acidMetaboliteC00049 (KEGG Compound)
L-aspartateMetaboliteC00049 (KEGG Compound)
Lysine biosynthesisPathway
MalateMetabolite617-48-1 (CAS) (S)-Malate
Malonate semialdehydeMetabolite33190 (ChEBI)
N-Acetyl-L-aspartateMetabolite
N-Carbamoyl-L-aspartateMetabolite15859 (ChEBI)
Nicotinate and nicotinamide metabolismPathway
O-AcetylcarnitineMetabolite3040-38-8 (CAS)
OxaloacetateMetaboliteC00036 (KEGG Compound)
PCGeneProductENSBTAG00000019700 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5091
Pantothenate and CoA biosynthesisPathway
Pyrimidine metabolismPathway
PyruvateMetabolite32816 (ChEBI)
Reductive carboxylate cycle (CO2 fixation)Pathway
Reductive carboxylate cycle (CO2 fixation)Pathway
Selenoamino acid metabolismPathway
SuccinateMetaboliteC00042 (KEGG Compound)
Urea cycel and metabolism of amino groupsPathwayWP497 (WikiPathways)
b-AlanineMetabolite6912-68-1 (CAS) beta-alanine
beta-Alanine metabolismPathway
tRNA (Asn)GeneProduct
tRNA(Asp)GeneProduct

Annotated Interactions

No annotated interactions
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