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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Depolarization Crossbreidge Reduction of intracellular Ca2+ concentration RELAXCATION Hyperpolarization Intravasal pressure /stretch Contraction Myofilaments Reduction of contractile system Ca2+ sensitivity Vasoconstrictors +p -p +p CaD CPI-17 RhOA Gs IRAG Ca2+ Calcium signal Pathway 20-HETE DAG Arachidonate Arachidonic acid metabolism IP3 CAMP Ca2+ Ca2+ cGMP PKG K+ Norepinephrine Angiotensin II Endothelin vasopressin Adenosine PGI2 CGRP Adrenomedullin K+ EET ANP BNP CNP NO CACNA1C CACNA1D CACNA1F CACNA1S KCNMA1 KCNU1 KCNMB1 KCNMB2 KCNMB3 KCNMB4 CALM CALM3 CALM1 CALML5 CALM2 CALML6 MYLK MYLK2 MYLK3 MYLK4 ACTA2 ACTG2 MAP2K1 MAP2K2 ARAF BRAF RAF1 GUCY1A2 GUCY1A3 GUCY1B3 PPP1CC PPP1CA PPP1CB PPP1R12A PPP1R12B PPP1R12C MYL6B MYL6 MYL9 MHC MAPK1 MAPK3 GNAQ GNA11 PLCB1 PLCB4 PLCB3 PLCB2 CYP4A11 CYP4A22 PLA2G1B PLA2G2D4 PLA2G2D1 PLA2G10 PLA2G3 PLA2G2A PLA2G5 PLA2G2E PLA2G2A PLA2G2C PLA2G2F PLA2G12A phospholipase A2 PLA2G12B phospholipase A2 PLA2G4E PLA2G4B PLA2G4F PLA2G4D PLA2G4A PLA2G6 ADRA1A ADRA1B ADRA1D AGTR1 EDNRA AVPR1A AVPR1B GNA12 GNA13 ARHGEF12 ARHGEF1 ARHGEF11 ROCK1 ROCK2 ADORA2A ADORA2B PTGIR CALCRL RAMP1 RAMP2 RAMP3 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 PRKACA PRKACB PRKX NPR-A NPR-B ITPR1 ITPR2 ITPR3 PRKCG PRKCA PRKCB PRKCD PRKCE PRKCH PRKCQ CACNA1F CACNA1D CACNA1S CACNA1C KCNMB2 KCNU1 KCNMB3 KCNMB4 KCNMB1 KCNMA1 ITPR2 ITPR1 ITPR3 MYLK2 MYLK MYLK4 MYLK3 Myosin ACTG2 ACTA2 MYL6 MHC MYL9 MYL6B Myosin PPP1CC PPP1CB PPP1R12C PPP1CA PPP1R12B PPP1R12A Vasodilators +p +p +p +p +p +p +p +p -p Name: Vascular smooth muscle contraction Organism: Bos taurus
Description
Vascular smooth muscle refers to the particular type of smooth muscle found within, and composing the majority of the wall of blood vessels. The main function of vascular smooth muscle tonus is to regulate the caliber of the blood vessels in the body. Excessive vasoconstriction leads to high blood pressure, while excessive vasodilation as in shock leads to low blood pressure (
http://en.wikipedia.org/wiki/Vascular_smooth_muscle ).
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