MFAP5-mediated ovarian cancer cell motility and invasiveness (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Leung CS, Yeung TL, Yip KP, Pradeep S, Balasubramanian L, Liu J, Wong KK, Mangala LS, Armaiz-Pena GN, Lopez-Berestein G, Sood AK, Birrer MJ, Mok SC; ''Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.''; Nat Commun, 2014 PubMed Europe PMC Scholia
2. Hornbeck PV, Zhang B, Murray B, Kornhauser JM, Latham V, Skrzypek E; ''PhosphoSitePlus, 2014: mutations, PTMs and recalibrations.''; Nucleic Acids Res, 2015 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	127230	view	20:08, 25 August 2023	Khanspers	added lit ref and updated description
	127188	view	22:11, 9 August 2023	Khanspers	updated phosphosites
	126996	view	19:27, 14 July 2023	Khanspers	clarify interactions, updated labels, some reactions
	120029	view	23:19, 15 October 2021	Khanspers	updated phosphosites
	108104	view	10:16, 29 November 2019	Fehrhart	Ontology Term : 'cancer pathway' added !
	106638	view	21:02, 12 September 2019	Khanspers	Modified description
	106199	view	12:09, 16 August 2019	MaintBot	HMDB identifier normalization
	105459	view	05:09, 8 August 2019	Khanspers	Modified description
	103743	view	20:48, 2 April 2019	Khanspers	Modified description
	103742	view	20:47, 2 April 2019	Khanspers	Modified description
	97674	view	11:23, 1 June 2018	AMTan	Ontology Term : 'ovarian cancer' added !
	94277	view	18:09, 30 August 2017	Khanspers	phosphorylations, updated for clarity
	87836	view	11:46, 25 July 2016	Elisa	Ontology Term : 'disease of cellular proliferation' added !
	87835	view	11:46, 25 July 2016	Elisa	Ontology Term : 'disease pathway' added !
	81279	view	04:54, 14 August 2015	Khanspers	Modified description
	81278	view	04:52, 14 August 2015	Khanspers	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
CREB5	GeneProduct	ENSG00000146592 (Ensembl)
Ca2+	Metabolite	HMDB00464 (HMDB)
DAG	Metabolite	HMDB07098 (HMDB)
ERK	GeneProduct	ENSG00000100030 (Ensembl)
FAK	GeneProduct	ENSG00000169398 (Ensembl)
IP3	Metabolite	85166-31-0 (CAS)
ITGAV	GeneProduct	ENSG00000138448 (Ensembl)
ITGB3	GeneProduct	ENSG00000259207 (Ensembl)
ITPR3	GeneProduct	ENSG00000096433 (Ensembl)
JUN	GeneProduct	ENSG00000177606 (Ensembl)
MFAP5	GeneProduct	ENSG00000197614 (Ensembl)
PIP2	Metabolite	245126-95-8 (CAS)
PLCG1	GeneProduct	ENSG00000124181 (Ensembl)
PRKCQ	GeneProduct	ENSG00000065675 (Ensembl)
RYR3	GeneProduct	ENSG00000198838 (Ensembl)
Troponin C	GeneProduct	ENSG00000114854 (Ensembl)

Annotated Interactions

No annotated interactions