Cytosine methylation (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none mutantwildtype IDH5-methylcytosine5-formylcytosine5-carboxylcytosineDNMT1a-ketoglutarate2-hydroxyglutarateisocitrateMECP2Mbd3ethanolhsa-mir-29aTET1TET3TET2TDGbase excision repairIDH1IDH25-hydroxymethylcytosinecytosineTET2TET3TET1TET2TET3TET1Name: Cytosine methylationOrganism: Homo sapiens


Description

No description

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Quality Tags

Image:Curated.pngReview changes for Approved

Ontology Terms

Pathway Ontology : regulatory pathway
 

Bibliography

  1. Wang J, Tang J, Lai M, Zhang H; ''5-Hydroxymethylcytosine and disease.''; Mutat Res Rev Mutat Res, 2014 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123390
Approved
view06:21, 23 July 2022EgonwMade a pathway clickable
106742view13:22, 17 September 2019MaintBotHMDB identifier normalization
94750view15:27, 5 October 2017Mkutmonfix unconnected lines
88828view12:18, 15 August 2016Fehrhartconverted elements of legend to graphical items
87217view14:25, 19 July 2016SusanOntology Term : 'regulatory pathway' added !
85533view07:47, 27 May 2016FehrhartAdded cellular compartments
84793view15:12, 22 March 2016FehrhartRemodelling finished (unconnected lines are in the legend)
84788view15:57, 21 March 2016Fehrhartintermediate save while remodelling
84784view12:31, 21 March 2016FehrhartRestructuring pathway - intermediate save
83745view15:39, 3 December 2015FehrhartModified description
83740view12:24, 3 December 2015FehrhartNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
2-hydroxyglutarateMetaboliteCHEBI:11596 (ChEBI)
5-carboxylcytosineMetaboliteCHEBI:76793 (ChEBI)
5-formylcytosineMetaboliteCHEBI:76794 (ChEBI)
5-hydroxymethylcytosineMetaboliteCHEBI:76792 (ChEBI)
5-methylcytosineMetaboliteHMDB02894 (HMDB)
DNMT1ProteinP26358 (Uniprot-TrEMBL)
IDH1ProteinO75874 (Uniprot-TrEMBL)
IDH2ProteinP48735 (Uniprot-TrEMBL)
MECP2ProteinP51608 (Uniprot-TrEMBL)
Mbd3ProteinO95983 (Uniprot-TrEMBL) as part of the NuRD complex
TDGProteinQ13569 (Uniprot-TrEMBL)
TET1ProteinQ8NFU7 (Uniprot-TrEMBL)
TET2ProteinQ6N021 (Uniprot-TrEMBL)
TET3ProteinK9JJH7 (Uniprot-TrEMBL)
a-ketoglutarateMetaboliteCHEBI:16810 (ChEBI) synonym oxoglutarate
base excision repairPathwayWP3399 (WikiPathways)
cytosineMetaboliteCHEBI:16040 (ChEBI)
ethanolMetaboliteCHEBI:16236 (ChEBI)
hsa-mir-29aRnaMIMAT0000086 (miRBase mature sequence)
isocitrateMetaboliteCHEBI:36453 (ChEBI)

Annotated Interactions

No annotated interactions

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