Hematopoietic stem cell gene regulation by GABP alpha/beta complex (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Yu S, Cui K, Jothi R, Zhao DM, Jing X, Zhao K, Xue HH; ''GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells.''; Blood, 2011 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	127709	view	19:58, 24 November 2023	Eweitz	Add more legend margin
	127708	view	19:55, 24 November 2023	Eweitz	Add legend margin to prevent overlap outside PathVisio
	127707	view	19:38, 24 November 2023	Eweitz	Tailor gene boxes, economize layout
	123358	view	04:46, 18 July 2022	Egonw	Made five pathways clickable
	120797	view	00:28, 9 January 2022	Eweitz	Use gene symbols, refine graphics and case
	117754	view	12:50, 22 May 2021	Eweitz	Modified title
	106590	view	19:32, 10 September 2019	Khanspers	Modified description
	105614	view	04:55, 10 August 2019	Khanspers	Modified description
	89276	view	06:49, 29 August 2016	Khanspers	layout, added auto-regulatory loop
	89067	view	08:39, 19 August 2016	Fehrhart	Fixed unconnected line
	88493	view	22:44, 10 August 2016	AAR&Co	Specify description
	88491	view	22:41, 10 August 2016	AAR&Co	Fixed Legend
	88490	view	22:40, 10 August 2016	AAR&Co	Fixed Legend
	88486	view	22:28, 10 August 2016	AAR&Co	Ontology Term : 'DNA modification pathway' added !
	88485	view	22:25, 10 August 2016	AAR&Co	Ontology Term : 'hematopoietic stem cell' added !
	88484	view	22:24, 10 August 2016	AAR&Co	Fixed Labels and interactions
	88481	view	22:16, 10 August 2016	AAR&Co	Periodical Save
	88479	view	22:08, 10 August 2016	AAR&Co	Periodical save, work in progress
	87198	view	11:46, 19 July 2016	Egonw	Changed the species to human, as all genes had human IDs.
	85925	view	18:17, 21 June 2016	AAR&Co	Fixed unconnected lines
	85924	view	18:15, 21 June 2016	AAR&Co	Modified description
	85802	view	23:39, 14 June 2016	AAR&Co	Modified description
	85797	view	22:12, 14 June 2016	AAR&Co	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
ATM	GeneProduct	ENSG00000149311 (Ensembl)
BCL2	GeneProduct	ENSG00000171791 (Ensembl)
BCL2L1	GeneProduct	ENSG00000171552 (Ensembl)
CREBBP	GeneProduct	ENSG00000005339 (Ensembl)
DNMT1	GeneProduct	ENSG00000130816 (Ensembl)
DNMT3A	GeneProduct	ENSG00000119772 (Ensembl)
DNMT3B	GeneProduct	ENSG00000088305 (Ensembl)
EP300	GeneProduct	ENSG00000100393 (Ensembl)
ETV6	GeneProduct	ENSG00000139083 (Ensembl)
FLT3	GeneProduct	ENSG00000122025 (Ensembl)
Foxo3a	Protein	O43524 (Uniprot-TrEMBL)
GABPA	GeneProduct	ENSG00000154727 (Ensembl)
GABPB	GeneProduct	ENSG00000104064 (Ensembl)	GABPB Not Specified
GZMB	GeneProduct	ENSG00000100453 (Ensembl)
MCL1	GeneProduct	ENSG00000143384 (Ensembl)
PTEN	GeneProduct	ENSG00000171862 (Ensembl)
SMAD4	GeneProduct	ENSG00000141646 (Ensembl)
SMARCA4	GeneProduct	ENSG00000127616 (Ensembl)
TERF2	GeneProduct	ENSG00000132604 (Ensembl)
ZFX	GeneProduct	ENSG00000005889 (Ensembl)

Annotated Interactions

No annotated interactions